D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 68 Citations 15,430 125 World Ranking 4968 National Ranking 2434

Research.com Recognitions

Awards & Achievements

2008 - Fellow of the American Academy of Arts and Sciences

1999 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Biochemistry
  • Genetics

Mary C. Beckerle mainly focuses on Cell biology, Zyxin, Cytoskeleton, Focal adhesion and Actin. His research integrates issues of Membrane protein, Cell adhesion, Cellular differentiation and LIM domain in his study of Cell biology. His work deals with themes such as Plasma protein binding, Nuclear localization sequence, Phosphoprotein and Zinc finger, which intersect with Zyxin.

Specifically, his work in Cytoskeleton is concerned with the study of Actin cytoskeleton. Mary C. Beckerle combines subjects such as Molecular biology, Integrin and Cell adhesion molecule with his study of Focal adhesion. His research in Actin intersects with topics in Actinin, Nebulin, Titin and Costamere.

His most cited work include:

  • Interaction of plasma membrane fibronectin receptor with talin—a transmembrane linkage (1032 citations)
  • The LIM domain: from the cytoskeleton to the nucleus (564 citations)
  • Striated muscle cytoarchitecture: an intricate web of form and function. (523 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Cell biology, Zyxin, Cytoskeleton, Actin and LIM domain. His Cell biology research integrates issues from Biochemistry, Actin cytoskeleton, Molecular biology, Integrin and Cell adhesion. His biological study spans a wide range of topics, including Nuclear export signal, Cancer research, Transcription factor and Signal transduction.

His Zyxin study is concerned with the larger field of Focal adhesion. The study incorporates disciplines such as Cytoplasm, Cell junction, PDZ domain, Extracellular matrix and Adherens junction in addition to Cytoskeleton. His Actin study integrates concerns from other disciplines, such as Actinin, Microfilament, Drosophila melanogaster and Biophysics, Myosin.

He most often published in these fields:

  • Cell biology (65.28%)
  • Zyxin (40.97%)
  • Cytoskeleton (36.81%)

What were the highlights of his more recent work (between 2011-2020)?

  • Cell biology (65.28%)
  • Zyxin (40.97%)
  • Cancer research (15.97%)

In recent papers he was focusing on the following fields of study:

Mary C. Beckerle spends much of his time researching Cell biology, Zyxin, Cancer research, Actin and Cytoskeleton. In his works, he undertakes multidisciplinary study on Cell biology and Platelet-derived growth factor receptor. His study on Zyxin is covered under Focal adhesion.

His Cancer research research incorporates themes from Cell growth, Keratin 17, Signal transduction, Cell adhesion and Sarcoma. His Actin research is multidisciplinary, incorporating perspectives in Actin remodeling, Biophysics, Myosin, Sarcomere and Stress fiber. His Cytoskeleton research is multidisciplinary, relying on both Mechanotransduction and LIM domain.

Between 2011 and 2020, his most popular works were:

  • Reversible LSD1 Inhibition Interferes with Global EWS/ETS Transcriptional Activity and Impedes Ewing Sarcoma Tumor Growth (93 citations)
  • Reversible LSD1 Inhibition Interferes with Global EWS/ETS Transcriptional Activity and Impedes Ewing Sarcoma Tumor Growth (93 citations)
  • Stretch-induced actin remodeling requires targeting of zyxin to stress fibers and recruitment of actin regulators. (84 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Genetics
  • Biochemistry

His scientific interests lie mostly in Focal adhesion, Cancer research, Sarcoma, Transcription factor and Stress fiber. His Cancer research research incorporates elements of Carcinogenesis, Suppressor and Epigenetics. The concepts of his Transcription factor study are interwoven with issues in Protein kinase B and Cell adhesion.

The study incorporates disciplines such as LIM domain, Actin cytoskeleton and Zyxin in addition to Stress fiber. His Actin cytoskeleton research incorporates themes from Mechanotransduction and Extracellular matrix. His Actin research extends to the thematically linked field of Zyxin.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Interaction of plasma membrane fibronectin receptor with talin—a transmembrane linkage

Alan Horwitz;Kimberly Duggan;Clayton Buck;Mary C. Beckerle.
Nature (1986)

1423 Citations

The LIM domain: from the cytoskeleton to the nucleus

Julie L. Kadrmas;Mary C. Beckerle.
Nature Reviews Molecular Cell Biology (2004)

885 Citations

Striated muscle cytoarchitecture: an intricate web of form and function.

Kathleen A. Clark;Abigail S. McElhinny;Mary C. Beckerle;Carol C. Gregorio.
Annual Review of Cell and Developmental Biology (2002)

766 Citations

The LIM domain is a modular protein-binding interface

Karen L. Schmeichel;Mary C. Beckerle.
Cell (1994)

630 Citations

Zyxin and cCRP: two interactive LIM domain proteins associated with the cytoskeleton.

Ingrid Sadler;Aaron W. Crawford;James W. Michelsen;Mary C. Beckerle.
Journal of Cell Biology (1992)

470 Citations

Mechanical force mobilizes zyxin from focal adhesions to actin filaments and regulates cytoskeletal reinforcement

Masaaki Yoshigi;Masaaki Yoshigi;Laura M. Hoffman;Laura M. Hoffman;Christopher C. Jensen;H. Joseph Yost;H. Joseph Yost.
Journal of Cell Biology (2005)

393 Citations

Colocalization of calcium-dependent protease II and one of its substrates at sites of cell adhesion

Mary C. Beckerle;Keith Burridge;George N. DeMartino;Dorothy E. Croall.
Cell (1987)

376 Citations

An interaction between zyxin and alpha-actinin.

Aaron W. Crawford;James W. Michelsen;Mary C. Beckerle.
Journal of Cell Biology (1992)

339 Citations

Nuclear–Cytoplasmic Shuttling of the Focal Contact Protein, Zyxin: A Potential Mechanism for Communication between Sites of Cell Adhesion and the Nucleus

David A. Nix;Mary C. Beckerle.
Journal of Cell Biology (1997)

305 Citations

Cysteine-Rich LIM-Only Proteins CRP1 and CRP2 Are Potent Smooth Muscle Differentiation Cofactors

David F. Chang;Narasimhaswamy S. Belaguli;Dinakar Iyer;Wilmer B. Roberts.
Developmental Cell (2003)

305 Citations

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