2026 Steven C. Ley: Biology and Biochemistry Researcher – H-Index, Publications & Awards

D-Index & Metrics

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	56	14252	13105	1118	1040	105	14299

Discipline name

D-Index

World Ranking

Current World Ranking

National Ranking

Current National Ranking

Publications

Citations

Biology and Biochemistry

14252

13105

1118

1040

105

14299

Biology and Biochemistry

D-Index

Citations

14299

World Ranking

14252

National Ranking

1118

Overview

Steven C. Ley is affiliated with Imperial College London in the United Kingdom. Their research contributions span multiple fields including Biochemistry, Genetics and Molecular Biology, Immunology and Microbiology, and Medicine. The scientist has produced work focused on Immunology, Molecular Biology, Dermatology, Physiology, and Oncology among subfields of study.

Their research addresses a range of main topics, highlighting Dermatology and Skin Diseases, Asthma and respiratory diseases, Phagocytosis and Immune Regulation, Immune Response and Inflammation, interferon and immune responses, Ferroptosis and cancer prognosis, and Psoriasis: Treatment and Pathogenesis.

Recent publications by Steven C. Ley include:

CARD14E138A signalling in keratinocytes induces TNF-dependent skin and systemic inflammation, 2020, eLife
TPL-2 kinase induces phagosome acidification to promote macrophage killing of bacteria, 2021, The EMBO Journal
Endothelial Tpl2 regulates vascular barrier function via JNK-mediated degradation of claudin-5 promoting neuroinflammation or tumor metastasis, 2021, Cell Reports
TPL-2 Inhibits IFN-β Expression via an ERK1/2-TCF-FOS Axis in TLR4-Stimulated Macrophages, 2022, The Journal of Immunology
p38γ and p38δ modulate innate immune response by regulating MEF2D activation, 2023, eLife

Their work is frequently published in venues such as eLife, The EMBO Journal, The Journal of Immunology, Cell Reports, and Biochemical Journal.

Steven C. Ley has collaborated regularly with several co-authors including Joan Manils, Michael J. Pattison, Paul A. O'Sullivan, Ashleigh Howes, and Julia Janzen.

Best Publications

Mitogen-activated protein kinases in innate immunity

J. Simon C. Arthur;Steven C. Ley

1787
Citations
Aggregation of Lipid Rafts Accompanies Signaling via the T Cell Antigen Receptor

Peter W. Janes;Steven C. Ley;Anthony I. Magee

1010
Citations
Functions of NF-κB1 and NF-κB2 in immune cell biology

Sören Beinke;Steven C. Ley

822
Citations
CD40 regulates the processing of NF-κB2 p100 to p52

H.J. Coope;P.G.P. Atkinson;B. Huhse;M. Belich

600
Citations
The role of lipid rafts in T cell antigen receptor (TCR) signalling

Peter W. Janes;Steven C. Ley;Anthony I. Magee;Panagiotis S. Kabouridis

572
Citations
S ‐acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes

Panagiotis S. Kabouridis;Anthony I. Magee;Steven C. Ley

458
Citations
Cholesterol depletion disrupts lipid rafts and modulates the activity of multiple signaling pathways in T lymphocytes

Panagiotis S. Kabouridis;Julia Janzen;Anthony L. Magee;Steven C. Ley

438
Citations
New insights into NF-κB regulation and function

Shao Cong Sun;Steven C. Ley

401
Citations
Activation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinase.

A. Salmeron;T. B. Ahmad;G. W. Carlile;D. Pappin

399
Citations
Isoforms of 14-3-3 protein can form homo- and heterodimers in vivo and in vitro: implications for function as adapter proteins

David H. Jones;Steven Ley;Alastair Aitken

347
Citations
Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)

Matthew E. Cockman;David E. Lancaster;Ineke P. Stolze;Kirsty S. Hewitson

333
Citations
Lipopolysaccharide Activation of the TPL-2/MEK/Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase Cascade Is Regulated by IκB Kinase-Induced Proteolysis of NF-κB1 p105

S. Beinke;M. J. Robinson;M. Hugunin;S. C. Ley

282
Citations
TPL-2 kinase regulates the proteolysis of the NF-κB-inhibitory protein NF-κB1 p105

Mônica P. Belich;Andrés Salmerón;Leland H. Johnston;Steven C. Ley

269
Citations
Palmitoylation of multiple Src-family kinases at a homologous N-terminal motif

M Koegl;P Zlatkine;S C Ley;S A Courtneidge

267
Citations
Expression, biological activities and mechanisms of action of A20 (TNFAIP3)

Lynn Verstrepen;Kelly Verhelst;Geert van Loo;Isabelle Carpentier

240
Citations
Immortalized B lymphocytes produce B-cell growth factor.

John Gordon;Steven C. Ley;Mark D. Melamed;Leonard S. English

227
Citations
Distinct intracellular localization of Lck and Fyn protein tyrosine kinases in human T lymphocytes.

Steven C. Ley;Mark Marsh;Chris R. Bebbington;Karen Proudfoot

223
Citations
TPL-2 negatively regulates interferon-β production in macrophages and myeloid dendritic cells

Frank Kaiser;Dorthe Cook;Stamatia Papoutsopoulou;Ricardo Rajsbaum

209
Citations
βTrCP-Mediated Proteolysis of NF-κB1 p105 Requires Phosphorylation of p105 Serines 927 and 932

Valerie Lang;Julia Janzen;Gregory Zvi Fischer;Yasmina Soneji

194
Citations
Direct Phosphorylation of NF-κB1 p105 by the IκB Kinase Complex on Serine 927 Is Essential for Signal-induced p105 Proteolysis

Andrés Salmerón;Julia Janzen;Yasmina Soneji;Nancy Bump

189
Citations