What is he best known for?
The fields of study he is best known for:
The scientist’s investigation covers issues in Cell biology, Signal transduction, Transcription factor, Regulation of gene expression and NFKB1.
His study in Cell biology is interdisciplinary in nature, drawing from both Transcription factor II A and Transcription Factor TFIID.
His biological study spans a wide range of topics, including Tumor necrosis factor alpha, Molecular biology, Receptor and Neuroscience.
His Transcription factor study incorporates themes from Promoter, Innate immune system and Binding site.
Alexander Hoffmann combines subjects such as Inflammation, Gene expression and Gene isoform with his study of Regulation of gene expression.
His work is dedicated to discovering how NFKB1, Regulator are connected with Hedgehog signaling pathway and other disciplines.
His most cited work include:
- The IκB-NF-κB Signaling Module: Temporal Control and Selective Gene Activation (1570 citations)
- Circuitry of nuclear factor kappaB signaling. (722 citations)
- Molecular Determinants of Crosstalk between Nuclear Receptors and Toll-like Receptors (560 citations)
What are the main themes of his work throughout his whole career to date?
Cell biology, Signal transduction, Transcription factor, NFKB1 and Genetics are his primary areas of study.
His work carried out in the field of Cell biology brings together such families of science as Molecular biology and Gene expression.
His research in Signal transduction intersects with topics in Inflammation, Immunology, Transcription Factor RelA, Regulator and Regulation of gene expression.
The Transcription factor study combines topics in areas such as Promoter, Receptor, Neuroscience and Immune system.
His study looks at the relationship between NFKB1 and topics such as Cellular differentiation, which overlap with RELB.
His TAF1 study combines topics from a wide range of disciplines, such as Transcription Factor TFIID, TATA box and TATA-Box Binding Protein.
He most often published in these fields:
- Cell biology (53.27%)
- Signal transduction (35.18%)
- Transcription factor (29.15%)
What were the highlights of his more recent work (between 2017-2021)?
- Cell biology (53.27%)
- Transcription factor (29.15%)
- Gene (15.58%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are Cell biology, Transcription factor, Gene, Immune system and Cytokine.
The study incorporates disciplines such as Enhancer, Gene expression, Inflammation, Interferon and Receptor in addition to Cell biology.
His Interferon study integrates concerns from other disciplines, such as Transcription factor complex, Cancer cell, Signal transduction, Crosstalk and Neural crest.
Alexander Hoffmann is interested in Plasma cell differentiation, which is a field of Transcription factor.
He has included themes like Tumor necrosis factor alpha and Neuroscience in his Immune system study.
In his study, T-cell receptor, Inducer, CD3, Cytotoxic T cell and Adoptive cell transfer is strongly linked to IκBα, which falls under the umbrella field of Cytokine.
Between 2017 and 2021, his most popular works were:
- Nongenetic origins of cell-to-cell variability in B lymphocyte proliferation. (31 citations)
- A Regulatory Circuit Controlling the Dynamics of NFκB cRel Transitions B Cells from Proliferation to Plasma Cell Differentiation (22 citations)
- Signaling Crosstalk Mechanisms That May Fine-Tune Pathogen-Responsive NFκB (11 citations)
In his most recent research, the most cited papers focused on:
His scientific interests lie mostly in Cell biology, Gene, Cell, Transcription factor and Cytokine.
His research integrates issues of RNA splicing, Gene expression and Systems biology in his study of Cell biology.
His work in Gene covers topics such as Receptor which are related to areas like Tumor necrosis factor alpha, Immune system, Stimulation and Epigenome.
His Transcription factor research is multidisciplinary, relying on both Interferon and Crosstalk.
The various areas that Alexander Hoffmann examines in his Interferon study include Inflammation, Inducer, Signal transduction and IκBα.
In his work, NFKB1, Transcriptome, Enhancer and Effector is strongly intertwined with Chromatin, which is a subfield of Cytokine.
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