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Stanley H. Appel

Stanley H. Appel

Houston Methodist
United States

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Neuroscience 118 411 369 244 216 489 45780
Medicine 118 4085 3826 2239 2072 499 45938

Stanley H. Appel publications per year

The chart shows the history of publications by Stanley H. Appel between 1959 and 2025, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Stanley H. Appel published across 67 years, from 1959 to 2025, averaging 7.8 papers a year. Output peaked at 19 publications in 2006. 12 of the 525 publications appeared in the last two years.

No. of publications
5 10 15
Bar chart. Horizontal axis: year, 1959 to 2025. Vertical axis: number of publications, 0 to 19. Peak 19 publications in 2006. 1959: 2 publications 1960: 0 publications 1961: 1 publication 1962: 0 publications 1963: 0 publications 1964: 3 publications 1965: 3 publications 1966: 1 publication 1967: 4 publications 1968: 6 publications 1969: 2 publications 1970: 6 publications 1971: 6 publications 1972: 3 publications 1973: 9 publications 1974: 10 publications 1975: 10 publications 1976: 14 publications 1977: 7 publications 1978: 12 publications 1979: 4 publications 1980: 5 publications 1981: 8 publications 1982: 4 publications 1983: 4 publications 1984: 3 publications 1985: 12 publications 1986: 7 publications 1987: 6 publications 1988: 9 publications 1989: 9 publications 1990: 7 publications 1991: 14 publications 1992: 12 publications 1993: 11 publications 1994: 8 publications 1995: 14 publications 1996: 12 publications 1997: 9 publications 1998: 7 publications 1999: 8 publications 2000: 10 publications 2001: 9 publications 2002: 10 publications 2003: 11 publications 2004: 16 publications 2005: 14 publications 2006: 19 publications 2007: 8 publications 2008: 8 publications 2009: 9 publications 2010: 10 publications 2011: 8 publications 2012: 8 publications 2013: 9 publications 2014: 10 publications 2015: 8 publications 2016: 10 publications 2017: 11 publications 2018: 11 publications 2019: 6 publications 2020: 9 publications 2021: 10 publications 2022: 12 publications 2023: 5 publications 2024: 8 publications 2025: 4 publications
1959 2025

525 publications in total across all disciplines

View publications per year as a table
Stanley H. Appel: publications per year, 1959 to 2025
Year Publications
1959 2
1960 0
1961 1
1962 0
1963 0
1964 3
1965 3
1966 1
1967 4
1968 6
1969 2
1970 6
1971 6
1972 3
1973 9
1974 10
1975 10
1976 14
1977 7
1978 12
1979 4
1980 5
1981 8
1982 4
1983 4
1984 3
1985 12
1986 7
1987 6
1988 9
1989 9
1990 7
1991 14
1992 12
1993 11
1994 8
1995 14
1996 12
1997 9
1998 7
1999 8
2000 10
2001 9
2002 10
2003 11
2004 16
2005 14
2006 19
2007 8
2008 8
2009 9
2010 10
2011 8
2012 8
2013 9
2014 10
2015 8
2016 10
2017 11
2018 11
2019 6
2020 9
2021 10
2022 12
2023 5
2024 8
2025 4
Total 525
Download as CSV

Stanley H. Appel publication distribution in Neuroscience in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Neuroscience in 2026. The highlighted bar marks where Stanley H. Appel sits on this spectrum.

No. of scientists
100 200 300 400 500
Bar chart with 86 bars. Horizontal axis: publications, 38–47 to 887+. Vertical axis: number of scientists, 0 to 539. Most scientists, 539, have 98–107 publications. The last bar groups every scientist with 887 publications or more. The highlighted bar, 488–497 publications, is where this scientist sits. 38–47 publications: 18 scientists 48–57 publications: 79 scientists 58–67 publications: 193 scientists 68–77 publications: 323 scientists 78–87 publications: 406 scientists 88–97 publications: 452 scientists 98–107 publications: 539 scientists 108–117 publications: 505 scientists 118–127 publications: 522 scientists 128–137 publications: 469 scientists 138–147 publications: 456 scientists 148–157 publications: 459 scientists 158–167 publications: 397 scientists 168–177 publications: 383 scientists 178–187 publications: 350 scientists 188–197 publications: 302 scientists 198–207 publications: 306 scientists 208–217 publications: 262 scientists 218–227 publications: 242 scientists 228–237 publications: 220 scientists 238–247 publications: 203 scientists 248–257 publications: 174 scientists 258–267 publications: 176 scientists 268–277 publications: 175 scientists 278–287 publications: 125 scientists 288–297 publications: 116 scientists 298–307 publications: 127 scientists 308–317 publications: 128 scientists 318–327 publications: 99 scientists 328–337 publications: 89 scientists 338–347 publications: 78 scientists 348–357 publications: 96 scientists 358–367 publications: 66 scientists 368–377 publications: 59 scientists 378–387 publications: 65 scientists 388–397 publications: 54 scientists 398–407 publications: 48 scientists 408–417 publications: 49 scientists 418–427 publications: 34 scientists 428–437 publications: 31 scientists 438–447 publications: 30 scientists 448–457 publications: 31 scientists 458–467 publications: 36 scientists 468–477 publications: 40 scientists 478–487 publications: 35 scientists 488–497 publications: 30 scientists 498–507 publications: 23 scientists 508–517 publications: 26 scientists 518–527 publications: 20 scientists 528–537 publications: 23 scientists 538–547 publications: 20 scientists 548–557 publications: 20 scientists 558–567 publications: 17 scientists 568–577 publications: 14 scientists 578–587 publications: 20 scientists 588–597 publications: 20 scientists 598–607 publications: 19 scientists 608–617 publications: 18 scientists 618–627 publications: 17 scientists 628–637 publications: 11 scientists 638–647 publications: 11 scientists 648–657 publications: 11 scientists 658–667 publications: 8 scientists 668–677 publications: 7 scientists 678–687 publications: 11 scientists 688–697 publications: 10 scientists 698–707 publications: 4 scientists 708–717 publications: 6 scientists 718–727 publications: 5 scientists 728–737 publications: 5 scientists 738–747 publications: 9 scientists 748–757 publications: 9 scientists 758–767 publications: 3 scientists 768–777 publications: 7 scientists 778–787 publications: 7 scientists 788–797 publications: 6 scientists 798–807 publications: 2 scientists 808–817 publications: 2 scientists 818–827 publications: 7 scientists 828–837 publications: 0 scientists 838–847 publications: 9 scientists 848–857 publications: 3 scientists 858–867 publications: 1 scientist 868–877 publications: 3 scientists 878–886 publications: 6 scientists 887+ publications: 100 scientists
38–47 publications 887+

This scientist: 489 publications — 94th percentile

94% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 887 publications or more.

View publications distribution as a table
Number of Neuroscience scientists by publication count, Research.com 2026 ranking edition. Based on 9,597 ranked scientists.
Publications Scientists This scientist
38–47 18
48–57 79
58–67 193
68–77 323
78–87 406
88–97 452
98–107 539
108–117 505
118–127 522
128–137 469
138–147 456
148–157 459
158–167 397
168–177 383
178–187 350
188–197 302
198–207 306
208–217 262
218–227 242
228–237 220
238–247 203
248–257 174
258–267 176
268–277 175
278–287 125
288–297 116
298–307 127
308–317 128
318–327 99
328–337 89
338–347 78
348–357 96
358–367 66
368–377 59
378–387 65
388–397 54
398–407 48
408–417 49
418–427 34
428–437 31
438–447 30
448–457 31
458–467 36
468–477 40
478–487 35
488–497 30 489
498–507 23
508–517 26
518–527 20
528–537 23
538–547 20
548–557 20
558–567 17
568–577 14
578–587 20
588–597 20
598–607 19
608–617 18
618–627 17
628–637 11
638–647 11
648–657 11
658–667 8
668–677 7
678–687 11
688–697 10
698–707 4
708–717 6
718–727 5
728–737 5
738–747 9
748–757 9
758–767 3
768–777 7
778–787 7
788–797 6
798–807 2
808–817 2
818–827 7
828–837 0
838–847 9
848–857 3
858–867 1
868–877 3
878–886 6
887+ 100
Download as CSV

Stanley H. Appel D-index placement in Neuroscience in 2026

The chart shows the D-index (discipline H-index) distribution of Neuroscience scientists ranked by Research.com in 2026. The highlighted bar marks where Stanley H. Appel sits on this spectrum.

No. of scientists
100 200 300 400 500
Bar chart with 68 bars. Horizontal axis: D-Index, 30–31 to 163+. Vertical axis: number of scientists, 0 to 512. Most scientists, 512, have 46–47 D-Index. The last bar groups every scientist with 163 D-Index or more. The highlighted bar, 118–119 D-Index, is where this scientist sits. 30–31 D-Index: 42 scientists 32–33 D-Index: 172 scientists 34–35 D-Index: 296 scientists 36–37 D-Index: 435 scientists 38–39 D-Index: 459 scientists 40–41 D-Index: 456 scientists 42–43 D-Index: 467 scientists 44–45 D-Index: 478 scientists 46–47 D-Index: 512 scientists 48–49 D-Index: 435 scientists 50–51 D-Index: 425 scientists 52–53 D-Index: 418 scientists 54–55 D-Index: 392 scientists 56–57 D-Index: 357 scientists 58–59 D-Index: 334 scientists 60–61 D-Index: 328 scientists 62–63 D-Index: 260 scientists 64–65 D-Index: 278 scientists 66–67 D-Index: 239 scientists 68–69 D-Index: 250 scientists 70–71 D-Index: 210 scientists 72–73 D-Index: 200 scientists 74–75 D-Index: 189 scientists 76–77 D-Index: 170 scientists 78–79 D-Index: 146 scientists 80–81 D-Index: 113 scientists 82–83 D-Index: 126 scientists 84–85 D-Index: 100 scientists 86–87 D-Index: 84 scientists 88–89 D-Index: 99 scientists 90–91 D-Index: 84 scientists 92–93 D-Index: 85 scientists 94–95 D-Index: 72 scientists 96–97 D-Index: 76 scientists 98–99 D-Index: 45 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 43 scientists 104–105 D-Index: 32 scientists 106–107 D-Index: 45 scientists 108–109 D-Index: 50 scientists 110–111 D-Index: 32 scientists 112–113 D-Index: 39 scientists 114–115 D-Index: 32 scientists 116–117 D-Index: 29 scientists 118–119 D-Index: 27 scientists 120–121 D-Index: 19 scientists 122–123 D-Index: 23 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 16 scientists 128–129 D-Index: 24 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 21 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 14 scientists 138–139 D-Index: 15 scientists 140–141 D-Index: 10 scientists 142–143 D-Index: 10 scientists 144–145 D-Index: 13 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 8 scientists 150–151 D-Index: 6 scientists 152–153 D-Index: 6 scientists 154–155 D-Index: 7 scientists 156–157 D-Index: 7 scientists 158–159 D-Index: 10 scientists 160–161 D-Index: 4 scientists 162 D-Index: 8 scientists 163+ D-Index: 100 scientists
30–31 D-Index 163+

This scientist: 118 D-Index — 96th percentile

96% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 163 D-Index or more.

View D-Index distribution as a table
Number of Neuroscience scientists by D-index, Research.com 2026 ranking edition. Based on 9,597 ranked scientists.
D-Index Scientists This scientist
30–31 42
32–33 172
34–35 296
36–37 435
38–39 459
40–41 456
42–43 467
44–45 478
46–47 512
48–49 435
50–51 425
52–53 418
54–55 392
56–57 357
58–59 334
60–61 328
62–63 260
64–65 278
66–67 239
68–69 250
70–71 210
72–73 200
74–75 189
76–77 170
78–79 146
80–81 113
82–83 126
84–85 100
86–87 84
88–89 99
90–91 84
92–93 85
94–95 72
96–97 76
98–99 45
100–101 49
102–103 43
104–105 32
106–107 45
108–109 50
110–111 32
112–113 39
114–115 32
116–117 29
118–119 27 118
120–121 19
122–123 23
124–125 27
126–127 16
128–129 24
130–131 13
132–133 21
134–135 17
136–137 14
138–139 15
140–141 10
142–143 10
144–145 13
146–147 9
148–149 8
150–151 6
152–153 6
154–155 7
156–157 7
158–159 10
160–161 4
162 8
163+ 100
Download as CSV

Overview

Stanley H. Appel is affiliated with Houston Methodist in the United States and has a significant body of research primarily focused on neurodegenerative diseases and neuroinflammation. Their work is situated mainly within the fields of Medicine and Neuroscience, with a concentrated interest in Neurology, Physiology, and Molecular Biology as subfields.

The scientist's research topics cover a range of neurodegenerative and neuroimmune mechanisms including:

  • Amyotrophic Lateral Sclerosis Research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Alzheimer's disease research and treatments
  • Tryptophan and brain disorders
  • Neurogenetic and Muscular Disorders Research
  • Parkinson's Disease Mechanisms and Treatments
  • S100 Proteins and Annexins

Stanley H. Appel has contributed to multiple publication venues, with notable frequency in:

  • Alzheimer's & Dementia
  • Neurology
  • Scandinavian Journal of Immunology
  • NeuroImmune Pharmacology and Therapeutics
  • Nature Reviews Neurology

Selected recent papers include:

  • "Restoring regulatory T-cell dysfunction in Alzheimer's disease through ex vivo expansion," 2020, Brain Communications
  • "Amyotrophic lateral sclerosis is a systemic disease: peripheral contributions to inflammation-mediated neurodegeneration," 2021, Current Opinion in Neurology
  • "Ex vivo expansion of dysfunctional regulatory T lymphocytes restores suppressive function in Parkinson's disease," 2021, npj Parkinson's Disease
  • "Elevated acute phase proteins reflect peripheral inflammation and disease severity in patients with amyotrophic lateral sclerosis," 2020, Scientific Reports
  • "Combined Regulatory T-Lymphocyte and IL-2 Treatment Is Safe, Tolerable, and Biologically Active for 1 Year in Persons With Amyotrophic Lateral Sclerosis," 2022, Neurology Neuroimmunology & Neuroinflammation

Frequent collaborators working alongside Stanley H. Appel include:

  • David R. Beers
  • Alireza Faridar
  • Jason R. Thonhoff
  • Weihua Zhao
  • Aaron D. Thome

Best Publications

  • Prevalence and patterns of cognitive impairment in sporadic ALS.

    G. M. Ringholz;Stanley H. Appel;M. Bradshaw;N. A. Cooke

  • Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways

    Elizabeth T. Cirulli;Brittany N Lasseigne;Slave Petrovski;Peter C Sapp

  • A unifying hypothesis for the cause of amyotrophic lateral sclerosis, Parkinsonism, and Alzheimer disease

    Stanley H. Appel

  • Natural history of amyotrophic lateral sclerosis in a database population. Validation of a scoring system and a model for survival prediction.

    Lanny J. Haverkamp;Vicki Appel;Stanley H. Appel

  • Mutant Mice (Quaking and Jimpy) with Deficient Myelination in the Central Nervous System

    Richard L. Sidman;Margaret M. Dickie;Stanley H. Appel

  • Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis

    David R. Beers;Jenny S. Henkel;Qin Xiao;Qin Xiao;Weihua Zhao

  • Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study

    James F Howard;Kimiaki Utsugisawa;Michael Benatar;Hiroyuki Murai

  • An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: A phase 1, randomised, first-in-man study

    Timothy M Miller;Alan Pestronk;William David;Jeffrey Rothstein

  • Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue.

    Jenny S. Henkel;Joseph I. Engelhardt;László Siklós;Ericka P. Simpson

  • Mutations in NR4A2 associated with familial Parkinson disease.

    Wei-dong Le;Pingyi Xu;Joseph Jankovic;Hong Jiang

  • Immune reactivity in a mouse model of familial ALS correlates with disease progression

    Maria E. Alexianu;Milena Kozovska;Stanley H. Appel

  • Catalog of the Neurological Mutants of the Mouse

    Richard L. Sidman;Margaret C. Green;Stanley H. Appel

  • CD4+ T cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited ALS

    David R. Beers;Jenny S. Henkel;Weihua Zhao;Jinghong Wang

  • Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum

    Yi He;Stanley H. Appel;Weidong Le

  • The role of calcium‐binding proteins in selective motoneuron vulnerability in amyotrophic lateral sclerosis

    Maria E. Alexianu;Bao‐Kuang ‐K Ho;A. Habib Mohamed;Vincenzo La Bella

  • Serum globulin in myasthenia gravis: Inhibition of α-bungarotoxin binding to acetylcholine receptors

    R.R. Almon;C.G. Andrew;S.H. Appel

  • Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS

    Bing Liao;Weihua Zhao;David R. Beers;Jenny S. Henkel

  • Endogenous regulatory T lymphocytes ameliorate amyotrophic lateral sclerosis in mice and correlate with disease progression in patients with amyotrophic lateral sclerosis

    David R. Beers;Jenny S. Henkel;Weihua Zhao;Jinghong Wang

  • Protein modification by the lipid peroxidation product 4-hydroxynonenal in the spinal cords of amyotrophic lateral sclerosis patients.

    Ward A. Pedersen;Weiming Fu;Jeffrey N. Keller;William R. Markesbery

  • Clinical Phenotypes of Different MPZ (P0) Mutations May Include Charcot–Marie–Tooth Type 1B, Dejerine–Sottas, and Congenital Hypomyelination

    Laura E Warner;Max J Hilz;Stanley H Appel;James M Killian

Frequent Co-Authors

Weidong Le
Weidong Le Chinese Academy of Sciences
Roy G. Smith
Roy G. Smith Scripps Research Institute
Allen D. Roses
Allen D. Roses Duke University
James L. McManaman
James L. McManaman University of Colorado Denver
Merit Cudkowicz
Merit Cudkowicz Harvard University
Joseph Jankovic
Joseph Jankovic Baylor College of Medicine
Robert G. Miller
Robert G. Miller California Pacific Medical Center
Alan Pestronk
Alan Pestronk Washington University in St. Louis
Jonathan D. Glass
Jonathan D. Glass Emory University
Tetsuo Ashizawa
Tetsuo Ashizawa Houston Methodist

External Links

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Combining neuroscience with these online degrees can create unique career profiles and open doors to fulfilling work in healthcare, therapy, and psychology.

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Orla Hardiman

Trinity College Dublin

Publications: 121

Pamela J. Shaw

Pamela J. Shaw

University of Sheffield

Publications: 105

Albert C. Ludolph

Albert C. Ludolph

University of Ulm

Publications: 103

Matthew C. Kiernan

Matthew C. Kiernan

Royal Prince Alfred Hospital

Publications: 93

Merit Cudkowicz

Merit Cudkowicz

Harvard University

Publications: 88

Ammar Al-Chalabi

Ammar Al-Chalabi

King's College London

Publications: 87

Adriano Chiò

Adriano Chiò

University of Turin

Publications: 86

Peter M Andersen

Peter M Andersen

Umeå University

Publications: 79

Weidong Le

Weidong Le

Chinese Academy of Sciences

Publications: 79

Leonard H. van den Berg

Leonard H. van den Berg

Utrecht University

Publications: 73

Mark P. Mattson

Mark P. Mattson

Johns Hopkins University

Publications: 71

Jan H. Veldink

Jan H. Veldink

Utrecht University

Publications: 63

Ronald W. Oppenheim

Ronald W. Oppenheim

Wake Forest University

Publications: 60

Michael J. Strong

Michael J. Strong

University of Michigan–Ann Arbor

Publications: 60

Christopher Shaw

Christopher Shaw

King's College London

Publications: 59

John R. Hodges

John R. Hodges

University of Sydney

Publications: 54

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