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Medicine

D-Index
115
Citations
49692
World Ranking
4534
National Ranking
173

Overview

Jan H. Veldink is a researcher affiliated with Utrecht University in the Netherlands. Their academic focus spans several interconnected fields, primarily within medicine and biochemistry, genetics, and molecular biology.

Their main fields of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these broader fields, their subfields of study emphasize:

  • Neurology
  • Genetics
  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Physiology

The topics central to their research involve:

  • Amyotrophic Lateral Sclerosis Research
  • Neurogenetic and Muscular Disorders Research
  • Neurological diseases and metabolism
  • Parkinson's Disease Mechanisms and Treatments
  • Genetic Associations and Epidemiology
  • Epigenetics and DNA Methylation
  • Genetic Neurodegenerative Diseases

Jan H. Veldink has contributed to numerous research papers, some of the recent publications include:

  • Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression (2021, Nature Genetics)
  • Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors (2020, Nature Genetics)
  • Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect (2021, Nature Genetics)
  • ExpansionHunter Denovo: a computational method for locating known and novel repeat expansions in short-read sequencing data (2020, Genome Biology)
  • Brain expression quantitative trait locus and network analyses reveal downstream effects and putative drivers for brain-related diseases (2023, Nature Genetics)

Their frequent collaborators include:

  • Pamela J. Shaw
  • Ammar Al-Chalabi
  • Philip Van Damme
  • Michael A. van Es
  • Wouter van Rheenen

Jan H. Veldink often publishes in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
  • Nature Genetics
  • Nature Communications
  • Neurology

Best Publications

  • A reference panel of 64,976 haplotypes for genotype imputation

    Shane McCarthy;Sayantan Das;Warren Kretzschmar;Olivier Delaneau

  • Genome-wide association study identifies five new schizophrenia loci

    Stephan Ripke;Alan R. Sanders;Kenneth S. Kendler;Douglas F. Levinson

  • Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

    Urmo Võsa;Annique Claringbould;Annique Claringbould;Harm-Jan Westra;Marc Jan Bonder

  • Systematic identification of trans eQTLs as putative drivers of known disease associations

    Harm-Jan Westra;Marjolein J Peters;Tõnu Esko;Hanieh Yaghootkar

  • Multiple common variants for celiac disease influencing immune gene expression

    Patrick C. A. Dubois;Gosia Trynka;Lude Franke;Lude Franke;Karen A. Hunt

  • Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways

    Elizabeth T. Cirulli;Brittany N Lasseigne;Slave Petrovski;Peter C Sapp

  • The genetic architecture of the human cerebral cortex

    Katrina L. Grasby;Neda Jahanshad;Jodie N. Painter;Lucía Colodro-Conde

  • Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

    Aude Nicolas;Kevin P. Kenna;Alan E. Renton;Alan E. Renton;Nicola Ticozzi

  • Whole-genome sequence variation, population structure and demographic history of the Dutch population

    Laurent C. Francioli;Androniki Menelaou;Sara L. Pulit;Freerk van Dijk

  • Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis

    Wouter van Rheenen;Aleksey Shatunov;Annelot M. Dekker;Russell L. McLaughlin

  • Controversies and priorities in amyotrophic lateral sclerosis

    Martin R Turner;Orla Hardiman;Michael Benatar;Benjamin R Brooks

  • Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis

    Võsa U;Claringbould A;Westra H;Bonder Mj

  • Prognosis for patients with amyotrophic lateral sclerosis: development and validation of a personalised prediction model

    Henk Jan Westeneng;Thomas P.A. Debray;Anne E. Visser;Ruben P.A. van Eijk

  • Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis.

    Michael A van Es;Jan H Veldink;Christiaan G J Saris;Hylke M Blauw

  • Disease variants alter transcription factor levels and methylation of their binding sites.

    Marc Jan Bonder;René Luijk;Daria V Zhernakova;Matthijs Moed

  • Identification of context-dependent expression quantitative trait loci in whole blood

    Daria V Zhernakova;Patrick Deelen;Martijn Vermaat;Maarten van Iterson

  • Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA.

    Rudolf S. N. Fehrmann;Ritsert C. Jansen;Jan H. Veldink;Harm-Jan Westra

  • Exome-wide rare variant analysis identifies TUBA4A mutations associated with familial ALS.

    B N Smith;N Ticozzi;C Fallini;A S Gkazi

  • Analysis of amyotrophic lateral sclerosis as a multistep process: a population-based modelling study

    Ammar Al-Chalabi;Andrea Calvo;Adriano Chio;Shuna Colville

  • Multidisciplinary ALS care improves quality of life in patients with ALS.

    J. P. Van den Berg;S. Kalmijn;E. Lindeman;J. H. Veldink

Frequent Co-Authors

Leonard H. van den Berg
Leonard H. van den Berg Utrecht University
Orla Hardiman
Orla Hardiman Trinity College Dublin
Ammar Al-Chalabi
Ammar Al-Chalabi King's College London
Roel A. Ophoff
Roel A. Ophoff University of California, Los Angeles
Christopher Shaw
Christopher Shaw King's College London
John Landers
John Landers University of Massachusetts Chan Medical School
Lude Franke
Lude Franke University Medical Center Groningen
Pamela J. Shaw
Pamela J. Shaw University of Sheffield
Adriano Chiò
Adriano Chiò University of Turin

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