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Philip Van Damme

Philip Van Damme

D-Index & Metrics

Medicine

D-Index
88
Citations
28302
World Ranking
13165
National Ranking
158

Overview

Philip Van Damme is affiliated with KU Leuven in Belgium and has contributed extensively to the field of medicine, with a focus on neurology and related subfields. Their research output prominently covers areas such as neurology, genetics, molecular biology, cellular and molecular neuroscience, and physiology.

The main topics of Philip Van Damme's research encompass:

  • Amyotrophic Lateral Sclerosis Research
  • Neurogenetic and Muscular Disorders Research
  • Parkinson's Disease Mechanisms and Treatments
  • Alzheimer's Disease Research and Treatments
  • Neurological Diseases and Metabolism
  • Hereditary Neurological Disorders
  • Genetic Neurodegenerative Diseases

They have frequently published in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
  • Journal of Neurology Neurosurgery & Psychiatry
  • Neurology
  • Brain

Philip Van Damme has collaborated with several coauthors multiple times, including:

  • Ammar Al-Chalabi
  • Jan H. Veldink
  • Orla Hardiman
  • Pamela J. Shaw
  • Ludo Van Den Bosch

Among their recent papers are:

  • Amyotrophic lateral sclerosis: a clinical review, 2020, European Journal of Neurology
  • Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS, 2022, New England Journal of Medicine
  • Phase 1-2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS, 2020, New England Journal of Medicine
  • TDP-43 proteinopathies: a new wave of neurodegenerative diseases, 2020, Journal of Neurology Neurosurgery & Psychiatry
  • Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility, 2022, Nature Genetics

Best Publications

  • EFNS guidelines on the Clinical Management of Amyotrophic Lateral Sclerosis (MALS) : revised report of an EFNS task force

    Peter M. Andersen;Sharon Abrahams;Gian D. Borasio;Mamede de Carvalho

  • Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study

    James F Howard;Kimiaki Utsugisawa;Michael Benatar;Hiroyuki Murai

  • Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

    Aude Nicolas;Kevin P. Kenna;Alan E. Renton;Alan E. Renton;Nicola Ticozzi

  • Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis

    Wouter van Rheenen;Aleksey Shatunov;Annelot M. Dekker;Russell L. McLaughlin

  • Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS

    Erik Storkebaum;Diether Lambrechts;Mieke Dewerchin;Maria-Paz Moreno-Murciano

  • Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs

    Jie Jiang;Jie Jiang;Qiang Zhu;Tania F. Gendron;Shahram Saberi

  • Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics

    Steven Boeynaems;Elke Bogaert;Denes Kovacs;Albert Konijnenberg

  • HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1–induced Charcot-Marie-Tooth disease

    Constantin van Outryve d'Ydewalle;Jyothsna Krishnan;Driss Chiheb;Philip Van Damme

  • Prognosis for patients with amyotrophic lateral sclerosis: development and validation of a personalised prediction model

    Henk Jan Westeneng;Thomas P.A. Debray;Anne E. Visser;Ruben P.A. van Eijk

  • Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival

    Philip van Damme;Annelies Van Hoecke;Diether Lambrechts;Peter Vanacker

  • Phase 1–2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS

    Timothy Miller;Merit Cudkowicz;Pamela J. Shaw;Peter M. Andersen

  • EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans

    Annelies Van Hoecke;Lies Schoonaert;Robin Lemmens;Mieke Timmers

  • HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients

    Wenting Guo;Maximilian Naujock;Maximilian Naujock;Laura Fumagalli;Tijs Vandoorne

  • Regional variation of Guillain-Barre syndrome

    Alex Y. Doets;Christine Verboon;Bianca Van Den Berg;Thomas Harbo

  • Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD

    Steven Boeynaems;Elke Bogaert;Emiel Michiels;Ilse Gijselinck

  • Oligodendrocyte dysfunction in the pathogenesis of amyotrophic lateral sclerosis

    Thomas Philips;Andre Bento-Abreu;Annelies Nonneman;Wanda Haeck

  • Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study

    Aleksey Shatunov;Kin Mok;Stephen Newhouse;Michael E Weale

  • Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity

    Philip Van Damme;Elke Bogaert;Maarten Dewil;Nicole Hersmus

  • Common and rare variant association analyses in Amyotrophic Lateral Sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

    Wouter van Rheenen;Rick A. A. van der Spek;Mark K. Bakker;Joke J. F. A. van Vugt

  • Genome-Wide Analyses Identify KIF5A as a Novel ALS Gene

    Aude Nicolas;Kevin P. Kenna;Alan E. Renton;Nicola Ticozzi

Frequent Co-Authors

Orla Hardiman
Orla Hardiman Trinity College Dublin
Ammar Al-Chalabi
Ammar Al-Chalabi King's College London
Jan H. Veldink
Jan H. Veldink Utrecht University
Leonard H. van den Berg
Leonard H. van den Berg Utrecht University
Adriano Chiò
Adriano Chiò University of Turin
Pamela J. Shaw
Pamela J. Shaw University of Sheffield
Christopher Shaw
Christopher Shaw King's College London
John Landers
John Landers University of Massachusetts Chan Medical School

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