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Ludo Van Den Bosch

Ludo Van Den Bosch

D-Index & Metrics

Biology and Biochemistry

D-Index
88
Citations
39133
World Ranking
2644
National Ranking
40

Overview

Ludo Van Den Bosch is affiliated with KU Leuven in Belgium and has contributed extensively to research in Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans multiple subfields including Neurology, Molecular Biology, Genetics, Cellular and Molecular Neuroscience, and Cell Biology.

Their research covers a range of main topics, particularly focusing on Amyotrophic Lateral Sclerosis Research, Neurogenetic and Muscular Disorders Research, RNA Research and Splicing, Hereditary Neurological Disorders, Neuroinflammation and Neurodegeneration Mechanisms, Histone Deacetylase Inhibitors Research, and Mitochondrial Function and Pathology.

Frequent co-authors collaborating with Ludo Van Den Bosch include:

  • Philip Van Damme
  • Katarina Stoklund Dittlau
  • Dietmar Rudolf Thal
  • Laura Fumagalli
  • Thomas G. Moens

Their work has been published predominantly in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Acta Neuropathologica
  • Brain
  • Acta Neuropathologica Communications
  • Radiotherapy and Oncology

Notable recent papers include:

  • "Hallmarks of neurodegenerative diseases," 2023, Cell
  • "TDP-43 proteinopathies: a new wave of neurodegenerative diseases," 2020, Journal of Neurology Neurosurgery & Psychiatry
  • "Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis," 2020, Molecular Cell
  • "Triad of TDP43 control in neurodegeneration: autoregulation, localization and aggregation," 2021, Nature Reviews Neuroscience
  • "Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation," 2022, Nature Immunology

Ludo Van Den Bosch has also contributed to book publications, including the title "Climate Risks, Exposure, Vulnerability and Resilience in Nepal" published in 2023 by Washington, DC: World Bank eBooks.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Protein Phase Separation: A New Phase in Cell Biology.

    Steven Boeynaems;Steven Boeynaems;Simon Alberti;Nicolas L. Fawzi;Tanja Mittag

  • Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration

    B. Oosthuyse;L. Moons;E. Storkebaum;H. Beck

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy

    Oleg V Evgrafov;Irena Mersiyanova;Joy Irobi;Ludo Van Den Bosch

  • Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

    Aude Nicolas;Kevin P. Kenna;Alan E. Renton;Alan E. Renton;Nicola Ticozzi

  • Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS

    Ana Jovičić;Jerome Mertens;Steven Boeynaems;Steven Boeynaems;Elke Bogaert;Elke Bogaert

  • Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS

    Erik Storkebaum;Diether Lambrechts;Mieke Dewerchin;Maria-Paz Moreno-Murciano

  • The role of excitotoxicity in the pathogenesis of amyotrophic lateral sclerosis

    L. Van Den Bosch;P. Van Damme;E. Bogaert;W. Robberecht

  • Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics

    Steven Boeynaems;Elke Bogaert;Denes Kovacs;Albert Konijnenberg

  • HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1–induced Charcot-Marie-Tooth disease

    Constantin van Outryve d'Ydewalle;Jyothsna Krishnan;Driss Chiheb;Philip Van Damme

  • Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy.

    Joy Irobi;Katrien Van Impe;Pavel Seeman;Albena Jordanova

  • Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival

    Philip van Damme;Annelies Van Hoecke;Diether Lambrechts;Peter Vanacker

  • Spontaneous driving forces give rise to protein-RNA condensates with coexisting phases and complex material properties.

    Steven Boeynaems;Alex S. Holehouse;Venera Weinhardt;Venera Weinhardt;Denes Kovacs

  • Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy.

    Albena Jordanova;Albena Jordanova;Joy Irobi;Florian P Thomas;Patrick Van Dijck

  • Minocycline delays disease onset and mortality in a transgenic model of ALS.

    Ludo Van Den Bosch;Petra Tilkin;Griet Lemmens;Wim Robberecht

  • EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans

    Annelies Van Hoecke;Lies Schoonaert;Robin Lemmens;Mieke Timmers

  • Calcium dysregulation in amyotrophic lateral sclerosis

    Julian Grosskreutz;Ludo Van Den Bosch;Bernhard U. Keller

  • Variants of the elongator protein 3 (ELP3) gene are associated with motor neuron degeneration

    Claire L. Simpson;Robin Lemmens;Robin Lemmens;Katarzyna Miskiewicz;Katarzyna Miskiewicz;Wendy J. Broom

  • Genome-Wide Analyses Identify KIF5A as a Novel ALS Gene

    Aude Nicolas;Kevin P. Kenna;Alan E. Renton;Nicola Ticozzi

Frequent Co-Authors

Peter Tompa
Peter Tompa Vrije Universiteit Brussel
Vincent Timmerman
Vincent Timmerman University of Antwerp
Frank Wuytack
Frank Wuytack KU Leuven
Ammar Al-Chalabi
Ammar Al-Chalabi King's College London

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