Frederic Rousseau

Overview

Best Publications

• The FoldX web server: an online force field

  Joost Schymkowitz;Jesper Borg;Francois Stricher;Robby Nys

  2672
  Citations

• Prediction of sequence-dependent and mutational effects on the aggregation of peptides and proteins

  Ana-Maria Fernandez-Escamilla;Frederic Rousseau;Joost Schymkowitz;Luis Serrano

  1743
  Citations

• Protein Phase Separation: A New Phase in Cell Biology.

  Steven Boeynaems;Steven Boeynaems;Simon Alberti;Nicolas L. Fawzi;Tanja Mittag

  1738
  Citations

• Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio.

  Inna Kuperstein;Kerensa Broersen;Kerensa Broersen;Iryna Benilova;Iryna Benilova;Iryna Benilova;Jef Rozenski

  675
  Citations

• The mechanism of γ-Secretase dysfunction in familial Alzheimer disease

  Lucía Chávez-Gutiérrez;Leen Bammens;Iryna Benilova;Annelies Vandersteen;Annelies Vandersteen

  599
  Citations

• Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics

  Steven Boeynaems;Elke Bogaert;Denes Kovacs;Albert Konijnenberg

  543
  Citations

• Protein aggregation and amyloidosis: confusion of the kinds?

  Frederic Rousseau;Joost Schymkowitz;Luis Serrano

  483
  Citations

• Gain of function of mutant p53 by coaggregation with multiple tumor suppressors

  Jie Xu;Joke Reumers;José R Couceiro;Frederik De Smet

  478
  Citations

• A comparative study of the relationship between protein structure and beta-aggregation in globular and intrinsically disordered proteins.

  Rune Linding;Joost Schymkowitz;Frederic Rousseau;Francesca Diella

  453
  Citations

• Prediction of water and metal binding sites and their affinities by using the Fold-X force field

  Joost W. H. Schymkowitz;Frederic Rousseau;Ivo C. Martins;Jesper Ferkinghoff-Borg

  406
  Citations

• Lipids revert inert Aβ amyloid fibrils to neurotoxic protofibrils that affect learning in mice

  Ivo Cristiano Martins;Inna Kuperstein;Hannah Wilkinson;Elke Maes

  395
  Citations

• How evolutionary pressure against protein aggregation shaped chaperone specificity

  Frederic Rousseau;Luis Serrano;Joost W.H. Schymkowitz

  355
  Citations

• The unfolding story of three-dimensional domain swapping.

  Frederic Rousseau;Joost W.H. Schymkowitz;Laura S. Itzhaki

  291
  Citations

• Restricted Location of PSEN2/γ-Secretase Determines Substrate Specificity and Generates an Intracellular Aβ Pool

  Ragna Sannerud;Cary Esselens;Paulina Ejsmont;Rafael Mattera

  289
  Citations

• SNPeffect 4.0: on-line prediction of molecular and structural effects of protein-coding variants

  Greet De Baets;Joost J. J. van Durme;Joke Reumers;Sebastian Maurer-Stroh

  288
  Citations

• Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD

  Steven Boeynaems;Elke Bogaert;Emiel Michiels;Ilse Gijselinck

  286
  Citations

• Structural Basis for Increased Toxicity of Pathological Aβ42:Aβ40 Ratios in Alzheimer Disease

  Kris Pauwels;Thomas L. Williams;Kyle L. Morris;Wim Jonckheere;Wim Jonckheere

  285
  Citations

• Three-dimensional domain swapping in p13suc1 occurs in the unfolded state and is controlled by conserved proline residues

  Frederic Rousseau;Joost Schymkowitz;Hannah Wilkinson;L.s. Itzhaki

  282
  Citations

• PupaSuite: finding functional single nucleotide polymorphisms for large-scale genotyping purposes

  Lucía Conde;Juan M. Vaquerizas;Hernán Dopazo;Leonardo Arbiza

  264
  Citations

• Exploring the sequence determinants of amyloid structure using position-specific scoring matrices (vol 7, pg 237, 2010)

  Sebastian Maurer-Stroh;Maja Debulpaep;Nico Kuemmerer;Manuela Lopez de la Paz

  2
  Citations