World's Best Scientists 2026 revealed!

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Biology and Biochemistry

D-Index
66
Citations
12439
World Ranking
8857
National Ranking
31

Overview

Jerson L. Silva is affiliated with the Federal University of Rio de Janeiro in Brazil. Their research spans multiple disciplines, primarily within Medicine and Biochemistry, Genetics and Molecular Biology.

The scientist's work covers several subfields, including Molecular Biology, Infectious Diseases, Oncology, Neurology, and Animal Science and Zoology. They focus on a variety of research topics, notably Cancer-related Molecular Pathways, RNA Research and Splicing, Prion Diseases and Protein Misfolding, SARS-CoV-2 and COVID-19 Research, Animal Virus Infections Studies, RNA modifications and cancer, and Epigenetics and DNA Methylation.

Among their recent papers are:

  • Targeting Biomolecular Condensation and Protein Aggregation against Cancer, 2023, Chemical Reviews
  • SARS-CoV-2 Spike protein induces TLR4-mediated long-term cognitive dysfunction recapitulating post-COVID-19 syndrome in mice, 2023, Cell Reports
  • Phase separation of p53 precedes aggregation and is affected by oncogenic mutations and ligands, 2021, Chemical Science
  • Oncogenic Gain of Function in Glioblastoma Is Linked to Mutant p53 Amyloid Oligomers, 2020, iScience
  • Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues, 2020, Molecules

Jerson L. Silva has coauthored frequently with several researchers, including Guilherme A. P. de Oliveira, Mayra A. Marques, Tuane C. R. G. Vieira, Andréa C. Oliveira, and André M. O. Gomes.

The scientist has published predominantly in venues such as bioRxiv (Cold Spring Harbor Laboratory), Brazilian Journal of Implantology and Health Sciences, iScience, Molecules, and Chemical Science.

Additionally, Silva has contributed to book publications, including a title with Springer Nature: Antiprotozoal Drug Development and Delivery (2022).

Best Publications

  • PRESSURE STABILITY OF PROTEINS

    Jerson L. Silva;Gregorio Weber

  • Pressure provides new insights into protein folding, dynamics and structure.

    Jerson L Silva;Debora Foguel;Catherine A Royer

  • Mutant p53 Aggregates into Prion-like Amyloid Oligomers and Fibrils IMPLICATIONS FOR CANCER

    Ana P.D. Ano Bom;Luciana P. Rangel;Danielly C.F. Costa;Guilherme A.P. de Oliveira

  • Pressure dissociation and conformational drift of the beta dimer of tryptophan synthase.

    Jerson L. Silva;Edith W. Miles;Gregorio Weber

  • DNA Converts Cellular Prion Protein into the β-Sheet Conformation and Inhibits Prion Peptide Aggregation

    Yraima Cordeiro;Filipe Machado;Luiz Juliano;Maria Aparecida Juliano

  • Cytosolic-free calcium elevation in Trypanosoma cruzi is required for cell invasion.

    S. N. J. Moreno;J. Silva;A. E. Vercesi;R. Docampo

  • The preaggregated state of an amyloidogenic protein: hydrostatic pressure converts native transthyretin into the amyloidogenic state.

    Astria D. Ferrão-Gonzales;Sandro O. Souto;Jerson L. Silva;Débora Foguel

  • Fibrillar Aggregates of the Tumor Suppressor p53 Core Domain

    Daniella Ishimaru;Leonardo R Andrade;Luciano S P Teixeira;Pablo A Quesado

  • Dissociation of amyloid fibrils of α-synuclein and transthyretin by pressure reveals their reversible nature and the formation of water-excluded cavities

    Débora Foguel;Marisa C. Suarez;Astria D. Ferrão-Gonzales;Thais C. R. Porto

  • High-Pressure Chemical Biology and Biotechnology

    Jerson L. Silva;Andrea C. Oliveira;Tuane C. R. G. Vieira;Guilherme A. P. de Oliveira

  • Prion-like aggregation of mutant p53 in cancer

    Jerson L. Silva;Claudia V. De Moura Gallo;Claudia V. De Moura Gallo;Danielly C.F. Costa;Luciana P. Rangel

  • Dissociation of a native dimer to a molten globule monomer. Effects of pressure and dilution on the association equilibrium of arc repressor.

    Jerson L. Silva;Cristina F. Silveira;Armindo Correia;Leila Pontes

  • The use of hydrostatic pressure as a tool to study viruses and other macromolecular assemblages

    Jerson L Silva;Debora Foguel;Andrea T Da Poian;Peter E Prevelige

  • Co-localization of mutant p53 and amyloid-like protein aggregates in breast tumors

    Claudia B. Levy;Claudia B. Levy;Ana C. Stumbo;Ana P.D. Ano Bom;Elisabeth A. Portari

  • Ligand binding and hydration in protein misfolding: insights from studies of prion and p53 tumor suppressor proteins.

    Jerson L. Silva;Tuane C. R. G. Vieira;Mariana P. B. Gomes;Ana Paula Ano Bom

  • Effects of hydrostatic pressure on a membrane-enveloped virus: high immunogenicity of the pressure-inactivated virus.

    J L Silva;P Luan;M Glaser;E W Voss

  • Arc Repressor will not Denature Under Pressure in the Absence of Water

    Andrea C. Oliveira;Luciane P. Gaspar;Andrea T. Da Poian;Jerson L. Silva

  • Low Temperature and Pressure Stability of Picornaviruses: Implications for Virus Uncoating

    Andréa C. Oliveira;Daniella Ishimaru;Rafael B. Gonçalves;Thomas J. Smith

  • Hydrostatic pressure rescues native protein from aggregates

    Debora Foguel;Clifford R. Robinson;Clifford R. Robinson;Pedro Caetano de Sousa;Jerson L. Silva

  • Hydration and Packing Effects on Prion Folding and β-Sheet Conversion HIGH PRESSURE SPECTROSCOPY AND PRESSURE PERTURBATION CALORIMETRY STUDIES

    Yraima Cordeiro;Julia Kraineva;Revanur Ravindra;Luís Maurício T.R. Lima

Frequent Co-Authors

Gregorio Weber
Gregorio Weber University of Illinois at Urbana-Champaign
Roland Winter
Roland Winter TU Dortmund University
John E. Johnson
John E. Johnson Scripps Research Institute
Peter E. Prevelige
Peter E. Prevelige University of Alabama at Birmingham
Jiri Jonas
Jiri Jonas University of Illinois at Urbana-Champaign
Hilal A. Lashuel
Hilal A. Lashuel École Polytechnique Fédérale de Lausanne
Lawrence B. Smillie
Lawrence B. Smillie University of Alberta
Jeffery W. Kelly
Jeffery W. Kelly Scripps Research Institute
Vilma R. Martins
Vilma R. Martins National Institute of Standards and Technology
Sergio Verjovski-Almeida
Sergio Verjovski-Almeida Universidade de São Paulo

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