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Medicine

D-Index
79
Citations
18237
World Ranking
17745
National Ranking
8855

Overview

Gregory T. MacLennan is affiliated with Case Western Reserve University in the United States. Their research primarily spans the broad field of Medicine, with significant contributions to Surgery, Pulmonary and Respiratory Medicine, Molecular Biology, Cancer Research, and Radiology, Nuclear Medicine and Imaging.

The scientist's work addresses various topics, notably:

  • Bladder and Urothelial Cancer Treatments
  • Urinary and Genital Oncology Studies
  • Prostate Cancer Treatment and Research
  • Prostate Cancer Diagnosis and Treatment
  • Cancer, Lipids, and Metabolism
  • Renal Cell Carcinoma Treatment
  • Radiomics and Machine Learning in Medical Imaging

Recent publications illustrate the focus areas and evolution of their research. Notable papers include:

  • "Oxidative Stress and Antioxidant Status in High-Risk Prostate Cancer Subjects" (2020, Diagnostics)
  • "The applicability and utility of immunohistochemical biomarkers in bladder pathology" (2020, Human Pathology)
  • "Androgen Deprivation Induces Transcriptional Reprogramming in Prostate Cancer Cells to Develop Stem Cell-Like Characteristics" (2020, International Journal of Molecular Sciences)
  • "Final results of a dose escalation protocol of stereotactic body radiotherapy for poor surgical candidates with localized renal cell carcinoma" (2020, Radiotherapy and Oncology)
  • "T1 and T2 MR fingerprinting measurements of prostate cancer and prostatitis correlate with deep learning-derived estimates of epithelium, lumen, and stromal composition on corresponding whole mount histopathology" (2020, European Radiology)

Frequent collaborators in their work include Lee Ponsky, Pingfu Fu, Eswar Shankar, Sanjay Gupta, and Shiv Verma, reflecting multi-author research projects and interdisciplinary collaboration.

Gregory T. MacLennan's research is regularly published in key academic journals. The top publication venues include:

  • The Journal of Urology
  • Cancer Research
  • Cancer Epidemiology Biomarkers & Prevention
  • European Radiology
  • Urology

The aggregation of research outputs suggests a consistent focus on oncological studies, especially related to bladder, prostate, and renal cancers. The integration of molecular biology techniques and imaging technologies points to a multidisciplinary approach in understanding cancer pathology and treatment modalities.

Best Publications

  • Molecular testing for BRAF mutations to inform melanoma treatment decisions: a move toward precision medicine.

    Liang Cheng;Antonio Lopez-Beltran;Francesco Massari;Gregory T MacLennan

  • Activation of PI3K‐Akt signaling pathway promotes prostate cancer cell invasion

    Sanjeev Shukla;Gregory T. MacLennan;Douglas J. Hartman;Pingfu Fu

  • Does the size of the surgical margin in partial nephrectomy for renal cell cancer really matter

    Suzette E. Sutherland;Martin I. Resnick;Gregory T. Maclennan;Howard B. Goldman

  • Loss of fragile histidine triad expression in colorectal carcinomas and premalignant lesions.

    Xing Pei Hao;Joseph E. Willis;Thomas G. Pretlow;J. Sunil Rao

  • Small cell carcinoma of the urinary bladder

    Liang Cheng;Chong-Xian Pan M.D.;Ximing J. Yang M.D.;Antonio Lopez-Beltran

  • Clear cell papillary renal cell carcinoma: a distinct histopathologic and molecular genetic entity.

    Stefano Gobbo;John N. Eble;David J. Grignon;Guido Martignoni

  • Molecular pathology of lung cancer: key to personalized medicine.

    Liang Cheng;Riley E Alexander;Gregory T MacLennan;Oscar W Cummings

  • OCT4: biological functions and clinical applications as a marker of germ cell neoplasia

    L. Cheng;M. T. Sung;P. Cossu-Rocca;T. D. Jones

  • Nuclear Factor-κB/p65 (Rel A) Is Constitutively Activated in Human Prostate Adenocarcinoma and Correlates with Disease Progression

    Sanjeev Shukla;Gregory T. MacLennan;Pingfu Fu;Jigar Patel

  • Union Internationale Contre le Cancer (UICC) and the American Joint TNM Staging of Renal Cell Committee on Cancer (AJCC) Carcinoma

    Patrick Guinan;Leslie H. Sobin;Ferran Algaba;Fausto Badellino

  • Atypical small acinar proliferation suspicious for malignancy in prostate needle biopsies: clinical significance in 33 cases

    Kenneth A. Iczkowski;Gregory T. Maclennan;David G. Bostwick

  • Tubulocystic carcinoma of the kidney: clinicopathologic analysis of 31 cases of a distinctive rare subtype of renal cell carcinoma.

    Mahul B. Amin;Gregory T. MacLennan;Ruta Gupta;David Grignon

  • Low-grade collecting duct carcinoma of the kidney : report of 13 cases of low-grade mucinous tubulocystic renal carcinoma of possible collecting duct origin

    Gregory T. MacLennan;George M. Farrow;George M. Farrow;David G. Bostwick;David G. Bostwick

  • Molecular Evidence Supporting Field Effect in Urothelial Carcinogenesis

    Timothy D. Jones;Mingsheng Wang;John N. Eble;Gregory T. MacLennan

  • Molecular genetic evidence for a common clonal origin of urinary bladder small cell carcinoma and coexisting urothelial carcinoma.

    Liang Cheng;Timothy D. Jones;Ryan P. McCarthy;John N. Eble

  • Bladder cancer: translating molecular genetic insights into clinical practice.

    Liang Cheng;Shaobo Zhang;Gregory T. MacLennan;Sean R. Williamson

  • The Influence of Chronic Inflammation in Prostatic Carcinogenesis: A 5-Year Followup Study

    Gregory T. MacLennan;Gregory T. MacLennan;Rosana Eisenberg;Ranleigh L. Fleshman;J. Michael Taylor

  • Optimized microvessel density analysis improves prediction of cancer stage from prostate needle biopsies

    David G. Bostwick;Thomas M. Wheeler;Michael Blute;David M. Barrett

  • Suppression of Prostate Carcinogenesis by Dietary Supplementation of Celecoxib in Transgenic Adenocarcinoma of the Mouse Prostate Model

    Sanjay Gupta;Vaqar M. Adhami;Murugesan Subbarayan;Gregory T. MacLennan

  • Differential Expression of S100A2 and S100A4 During Progression of Human Prostate Adenocarcinoma

    Sanjay Gupta;Tajamul Hussain;Gregory T. MacLennan;Pingfu Fu

Frequent Co-Authors

Liang Cheng
Liang Cheng Brown University
Antonio Lopez-Beltran
Antonio Lopez-Beltran University of Córdoba
Rodolfo Montironi
Rodolfo Montironi Marche Polytechnic University
Sanjay Gupta
Sanjay Gupta The University of Texas MD Anderson Cancer Center
John N. Eble
John N. Eble Indiana University
Puay Hoon Tan
Puay Hoon Tan Duke NUS Graduate Medical School
David G. Bostwick
David G. Bostwick Bostwick Laboratories
Eva Comperat
Eva Comperat Sorbonne University
Ximing J. Yang
Ximing J. Yang Northwestern University
Anant Madabhushi
Anant Madabhushi Emory University

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