Jeffery W. Kelly

Overview

Best Publications

• Adapting proteostasis for disease intervention.

  William E. Balch;Richard I. Morimoto;Andrew Dillin;Jeffery W. Kelly

  2884
  Citations

• The alternative conformations of amyloidogenic proteins and their multi-step assembly pathways

  Jeffery W Kelly

  1466
  Citations

• Biological and Chemical Approaches to Diseases of Proteostasis Deficiency

  Evan T. Powers;Richard I. Morimoto;Andrew Dillin;Jeffery W. Kelly

  1409
  Citations

• Functional amyloid--from bacteria to humans.

  Douglas M. Fowler;Atanas V. Koulov;William E. Balch;Jeffery W. Kelly

  1194
  Citations

• Therapeutic approaches to protein-misfolding diseases

  Fred E. Cohen;Jeffery W. Kelly

  1035
  Citations

• Antibody Domain Exchange Is an Immunological Solution to Carbohydrate Cluster Recognition

  Daniel A. Calarese;Christopher N. Scanlan;Michael B. Zwick;Songpon Deechongkit

  1013
  Citations

• Opposing Activities Protect Against Age-Onset Proteotoxicity

  Ehud Cohen;Jan Bieschke;Rhonda M. Perciavalle;Jeffery W. Kelly

  1008
  Citations

• Amyloid diseases: abnormal protein aggregation in neurodegeneration.

  Edward H. Koo;Peter T. Lansbury;Jeffery W. Kelly

  1006
  Citations

• Transthyretin Amyloid Cardiomyopathy: JACC State-of-the-Art Review

  Frederick L. Ruberg;Martha Grogan;Mazen Hanna;Jeffery W. Kelly

  1005
  Citations

• Functional amyloid formation within mammalian tissue

  Douglas M Fowler;Atanas V Koulov;Christelle Alory-Jost;Michael S Marks

  990
  Citations

• Alternative conformations of amyloidogenic proteins govern their behavior.

  Jeffery W Kelly

  917
  Citations

• Tafamidis for transthyretin familial amyloid polyneuropathy A randomized, controlled trial

  Teresa Coelho;Luis F. Maia;Ana Martins da Silva;Marcia Waddington Cruz

  898
  Citations

• Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade

  Christine E. Bulawa;Stephen Connelly;Michael DeVit;Lan Wang

  788
  Citations

• Repurposing Diflunisal for Familial Amyloid Polyneuropathy A Randomized Clinical Trial

  John L. Berk;Ole B. Suhr;Laura Obici;Yoshiki Sekijima

  775
  Citations

• Partial denaturation of transthyretin is sufficient for amyloid fibril formation in vitro

  Wilfredo Colon;Jeffery W. Kelly

  718
  Citations

• The Acid-Mediated Denaturation Pathway of Transthyretin Yields a Conformational Intermediate That Can Self-Assemble into Amyloid†

  Zhihong Lai;Wilfredo Colón;Jeffery W. Kelly

  704
  Citations

• Hsp90 Cochaperone Aha1 Downregulation Rescues Misfolding of CFTR in Cystic Fibrosis

  Xiaodong Wang;John Venable;Paul LaPointe;Darren M. Hutt

  691
  Citations

• Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss

  Maria Talantova;Sara Sanz-Blasco;Xiaofei Zhang;Peng Xia

  677
  Citations

• Semen-Derived Amyloid Fibrils Drastically Enhance HIV Infection

  Jan Münch;Elke Rücker;Ludger Ständker;Knut Adermann

  653
  Citations

• Chemical chaperones increase the cellular activity of N370S β-glucosidase: A therapeutic strategy for Gaucher disease

  Anu R. Sawkar;Wei-Chieh Cheng;Ernest Beutler;Chi-Huey Wong

  637
  Citations