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Molecular Biology
USA
2026

D-Index & Metrics

Molecular Biology

D-Index
146
Citations
81578
World Ranking
95
National Ranking
60

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in United States Leader Award
  • 2025 - Research.com Molecular Biology in United States Leader Award
  • 2023 - Research.com Molecular Biology in United States Leader Award
  • 2011 - Fellow of the American Academy of Arts and Sciences
  • 1998 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Richard I. Morimoto is affiliated with Northwestern University in the United States. Their research primarily spans the fields of biochemistry, genetics, and molecular biology, as well as medicine.

The areas of study covered in their work include:

  • Molecular Biology
  • Pulmonary and Respiratory Medicine
  • Cellular and Molecular Neuroscience
  • Physiology
  • Epidemiology

Main topics of their research focus on:

  • Genetics, Aging, and Longevity in Model Organisms
  • Mitochondrial Function and Pathology
  • Autophagy in Disease and Therapy
  • Endoplasmic Reticulum Stress and Disease
  • Genetic Neurodegenerative Diseases
  • RNA Research and Splicing
  • Ubiquitin and proteasome pathways

Frequent coauthors who have collaborated with Morimoto include:

  • Rogan A. Grant
  • Laura C. Bott
  • Hiam Abdala-Valencia
  • G. R. Scott Budinger
  • Ambre J. Sala

The scientist has published extensively in several venues, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • The Journal of Cell Biology
  • Nature Aging
  • Genes & Development

Some recent notable publications by Richard I. Morimoto include:

  • "Autophagy in healthy aging and disease," 2021, Nature Aging
  • "The lung microenvironment shapes a dysfunctional response of alveolar macrophages in aging," 2021, Journal of Clinical Investigation
  • "Aging is associated with a systemic length-associated transcriptome imbalance," 2022, Nature Aging
  • "Resetting proteostasis with ISRIB promotes epithelial differentiation to attenuate pulmonary fibrosis," 2021, Proceedings of the National Academy of Sciences
  • "Challenging Proteostasis: Role of the Chaperone Network to Control Aggregation-Prone Proteins in Human Disease," 2020, Advances in experimental medicine and biology

Richard I. Morimoto has received recognitions such as election as a Fellow of the American Association for the Advancement of Science (AAAS) in 1998 and as a Fellow of the American Academy of Arts and Sciences in 2011.

Best Publications

  • Adapting proteostasis for disease intervention.

    William E. Balch;Richard I. Morimoto;Andrew Dillin;Jeffery W. Kelly

  • Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators

    Richard I. Morimoto

  • Geroscience: Linking Aging to Chronic Disease

    Brian K. Kennedy;Shelley L. Berger;Anne Brunet;Judith Campisi;Judith Campisi

  • The Biology of heat shock proteins and molecular chaperones.

    Richard I. Morimoto;Alfred Tissières;Costa Georgopoulos

  • Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome.

    Helen M. Beere;Beni B. Wolf;Kelvin Cain;Dick D. Mosser

  • Cells in stress: transcriptional activation of heat shock genes.

    Richard I. Morimoto

  • Heat shock factors: integrators of cell stress, development and lifespan

    Malin Åkerfelt;Richard I. Morimoto;Lea Sistonen

  • Biological and Chemical Approaches to Diseases of Proteostasis Deficiency

    Evan T. Powers;Richard I. Morimoto;Andrew Dillin;Jeffery W. Kelly

  • Role of the Heat Shock Response and Molecular Chaperones in Oncogenesis and Cell Death

    Caroline Jolly;Richard I. Morimoto

  • The Biology of Proteostasis in Aging and Disease

    Johnathan Labbadia;Richard I. Morimoto

  • Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the absence of stress.

    Kevin D. Sarge;Shawn P. Murphy;Richard I. Morimoto

  • Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70.

    Clayton Hunt;Richard I. Morimoto

  • Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging

    Richard I. Morimoto

  • The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans

    James F. Morley;Heather R. Brignull;Jill J. Weyers;Richard I. Morimoto

  • Chaperoning signaling pathways: Molecular chaperones as stress-sensing 'heat shock' proteins

    Ellen A. A. Nollen;Richard I. Morimoto

  • The chaperone function of hsp70 is required for protection against stress-induced apoptosis.

    Dick D. Mosser;Antoine W. Caron;Lucie Bourget;Anatoli B. Meriin

  • Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span.

    Alexander V. Misharin;Luisa Morales-Nebreda;Paul A. Reyfman;Carla M. Cuda

  • Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones.

    James F. Morley;Richard I. Morimoto

  • Autophagy in healthy aging and disease

    Yahyah Aman;Yahyah Aman;Tomas Schmauck-Medina;Malene Hansen;Richard I. Morimoto

  • 1 Progress and Perspectives on the Biology of Heat Shock Proteins and Molecular Chaperones

    Richard I. Morimoto;Alfred Tissières;Costa Georgopoulos

Frequent Co-Authors

Richard B. Silverman
Richard B. Silverman Northwestern University
William E. Balch
William E. Balch Scripps Health
Kevin D. Sarge
Kevin D. Sarge University of Kentucky
Lea Sistonen
Lea Sistonen Åbo Akademi University
Jacob I. Sznajder
Jacob I. Sznajder Northwestern University
Michele Vendruscolo
Michele Vendruscolo University of Cambridge
Murray Rabinowitz
Murray Rabinowitz University of Chicago
Kazuhiro Nagata
Kazuhiro Nagata Kyoto Sangyo University
G. R. Scott Budinger
G. R. Scott Budinger Northwestern University
Navdeep S. Chandel
Navdeep S. Chandel Northwestern University

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