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Kazuhiro Nagata

Kazuhiro Nagata

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Biology and Biochemistry
Japan
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
95
Citations
46386
World Ranking
1868
National Ranking
106

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2025 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2023 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Kazuhiro Nagata is affiliated with Kyoto Sangyo University in Japan. Their research primarily focuses on biochemistry, genetics, and molecular biology, with substantial contributions to medicine.

The main subfields of their work include molecular biology, cell biology, physiology, neurology, and epidemiology. Central topics in their research involve endoplasmic reticulum stress and disease, heat shock proteins research, autophagy in disease and therapy, proteins in food systems, enzyme structure and function, photosynthetic processes and mechanisms, and ATP synthase and ATPases research.

Recent publications by Nagata include the following papers:

  • Hsp47 promotes cancer metastasis by enhancing collagen-dependent cancer cell-platelet interaction (2020), Proceedings of the National Academy of Sciences
  • ERdj8 governs the size of autophagosomes during the formation process (2020), The Journal of Cell Biology
  • Quality Control of Procollagen in Cells (2021), Annual Review of Biochemistry
  • Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail (2020), Science Advances
  • Redox states in the endoplasmic reticulum directly regulate the activity of calcium channel, inositol 1,4,5-trisphosphate receptors (2023), Proceedings of the National Academy of Sciences

Frequent publication venues for Nagata include:

  • Proceedings of the National Academy of Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Cell Biology
  • Annual Review of Biochemistry
  • Science Advances

Frequent co-authors collaborating with Nagata are:

  • Ryo Ushioda
  • M. Inoue
  • Kenji Inaba
  • Shinya Ito
  • Akihisa Tsutsumi

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum

    Stefan J. Marciniak;Chi Y. Yun;Seiichi Oyadomari;Isabel Novoa

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • A Time-Dependent Phase Shift in the Mammalian Unfolded Protein Response

    Hiderou Yoshida;Toshie Matsui;Nobuko Hosokawa;Randal J. Kaufman

  • Identification of RNF213 as a Susceptibility Gene for Moyamoya Disease and Its Possible Role in Vascular Development

    Wanyang Liu;Daisuke Morito;Seiji Takashima;Yohei Mineharu

  • A novel ER α-mannosidase-like protein accelerates ER-associated degradation

    Nobuko Hosokawa;Ikuo Wada;Kiyotaka Hasegawa;Tetuya Yorihuzi

  • EDEM As an Acceptor of Terminally Misfolded Glycoproteins Released from Calnexin

    Yukako Oda;Nobuko Hosokawa;Ikuo Wada;Kazuhiro Nagata

  • Protein Folding and Quality Control in the ER

    Kazutaka Araki;Kazuhiro Nagata

  • HSF4, a new member of the human heat shock factor family which lacks properties of a transcriptional activator.

    A Nakai;M Tanabe;Y Kawazoe;J Inazawa

  • Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation.

    Yukako Oda;Tetsuya Okada;Hiderou Yoshida;Randal J. Kaufman;Randal J. Kaufman

  • ERdj5 Is Required as a Disulfide Reductase for Degradation of Misfolded Proteins in the ER

    Ryo Ushioda;Jun Hoseki;Kazutaka Araki;Gregor Jansen

  • Hsp47: a collagen-specific molecular chaperone

    Kazuhiro Nagata

  • Cell surface receptors for extracellular matrix components.

    Steven K. Akiyama;Kazuhiro Nagata;Kenneth M. Yamada

  • Embryonic lethality of molecular chaperone hsp47 knockout mice is associated with defects in collagen biosynthesis.

    Naoko Nagai;Masanori Hosokawa;Shigeyoshi Itohara;Eijiro Adachi

  • EDEM3, a Soluble EDEM Homolog, Enhances Glycoprotein Endoplasmic Reticulum-associated Degradation and Mannose Trimming

    Kazuyoshi Hirao;Yuko Natsuka;Taku Tamura;Ikuo Wada

  • Involvement of the stress protein HSP47 in procollagen processing in the endoplasmic reticulum.

    Akira Nakai;Mamoru Satoh;Kazunori Hirayoshi;Kazuhiro Nagata

  • Cytosolic chaperonin prevents polyglutamine toxicity with altering the aggregation state

    Akira Kitamura;Hiroshi Kubota;Chan Gi Pack;Gen Matsumoto

  • Benzylidene lactam compound, KNK437, a novel inhibitor of acquisition of thermotolerance and heat shock protein induction in human colon carcinoma cells.

    Shin-ichi Yokota;Mikio Kitahara;Kazuhiro Nagata

  • Inhibition of the activation of heat shock factor in vivo and in vitro by flavonoids.

    Nobuko Hosokawa;Kazunori Hirayoshi;Hitoshi Kudo;Hajime Takechi

Frequent Co-Authors

Akira Nakai
Akira Nakai Yamaguchi University
Koichi Kato
Koichi Kato National Institutes of Natural Sciences
Richard I. Morimoto
Richard I. Morimoto Northwestern University
Tohru Natsume
Tohru Natsume National Institute of Advanced Industrial Science and Technology
Kenji Inaba
Kenji Inaba University of Southern California
Hans Peter Bächinger
Hans Peter Bächinger Oregon Health & Science University
Kenneth M. Yamada
Kenneth M. Yamada National Institutes of Health
Masataka Kinjo
Masataka Kinjo Hokkaido University
Ikuo Wada
Ikuo Wada Fukushima Medical University
Tamotsu Yoshimori
Tamotsu Yoshimori Osaka University

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