2026 Kazutoshi Mori: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	92	2167	1967	126	114	228	44327

Overview

Kazutoshi Mori is affiliated with Kyoto University in Japan. The primary research focuses on biochemistry, genetics, and molecular biology, with significant work in medicine. Mori's areas of expertise include cell biology, molecular biology, physiology, epidemiology, and genetics.

The scientist's main research topics are diverse and include:

Endoplasmic Reticulum Stress and Disease
Cellular transport and secretion
Glycosylation and Glycoproteins Research
Autophagy in Disease and Therapy
Pancreatic function and diabetes
Galectins and Cancer Biology
Lysosomal Storage Disorders Research

Mori has published extensively, with notable papers including:

"Mechanisms of productive folding and endoplasmic reticulum-associated degradation of glycoproteins and non-glycoproteins," 2020, Biochimica et Biophysica Acta (BBA) - General Subjects
"EDEM2 stably disulfide-bonded to TXNDC11 catalyzes the first mannose trimming step in mammalian glycoprotein ERAD," 2020, eLife
"Endoplasmic Reticulum-Associated Degradation Controls Virus Protein Homeostasis, Which Is Required for Flavivirus Propagation," 2021, Journal of Virology
"Antipsychotic olanzapine-induced misfolding of proinsulin in the endoplasmic reticulum accounts for atypical development of diabetes," 2020, eLife
"Purified EDEM3 or EDEM1 alone produces determinant oligosaccharide structures from M8B in mammalian glycoprotein ERAD," 2021, eLife

Frequent publication venues for Mori's work include:

eLife
bioRxiv (Cold Spring Harbor Laboratory)
Cell Structure and Function
Research Square (Research Square)
Journal of Gastroenterology and Hepatology

Mori collaborates often with several researchers, including Tokiro Ishikawa, Satoshi Ninagawa, Shunsuke Saito, Tetsuya Okada, and Mika Takarada-Iemata.

Best Publications

XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription Factor

Hiderou Yoshida;Toshie Matsui;Akira Yamamoto;Tetsuya Okada

4524
Citations
Mammalian Transcription Factor ATF6 Is Synthesized as a Transmembrane Protein and Activated by Proteolysis in Response to Endoplasmic Reticulum Stress

Kyosuke Haze;Hiderou Yoshida;Hideki Yanagi;Takashi Yura

2433
Citations
Identification of the cis-Acting Endoplasmic Reticulum Stress Response Element Responsible for Transcriptional Induction of Mammalian Glucose-regulated Proteins INVOLVEMENT OF BASIC LEUCINE ZIPPER TRANSCRIPTION FACTORS

Hiderou Yoshida;Kyosuke Haze;Hideki Yanagi;Takashi Yura

1804
Citations
Tripartite Management of Unfolded Proteins in the Endoplasmic Reticulum

Kazutoshi Mori

1320
Citations
IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

Kyungho Lee;Witoon Tirasophon;Xiaohua Shen;Marek Michalak

1276
Citations
Transcriptional Induction of Mammalian ER Quality Control Proteins Is Mediated by Single or Combined Action of ATF6α and XBP1

Keisuke Yamamoto;Takashi Sato;Toshie Matsui;Masanori Sato

1174
Citations
ATF6 Activated by Proteolysis Binds in the Presence of NF-Y (CBF) Directly to the cis-Acting Element Responsible for the Mammalian Unfolded Protein Response

Hiderou Yoshida;Tetsuya Okada;Kyosuke Haze;Hideki Yanagi

1160
Citations
AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1

Kiichi Hirota;Minoru Matsui;Satoshi Iwata;Akira Nishiyama

1029
Citations
Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins.

D. Thomas Rutkowski;Stacey M Arnold;Corey N. Miller;Jun-Dong Wu

911
Citations
A Time-Dependent Phase Shift in the Mammalian Unfolded Protein Response

Hiderou Yoshida;Toshie Matsui;Nobuko Hosokawa;Randal J. Kaufman

853
Citations
Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development

Xiaohua Shen;Ronald E. Ellis;Kyungho Lee;Chuan Yin Liu

807
Citations
Distinct roles of thioredoxin in the cytoplasm and in the nucleus. A two-step mechanism of redox regulation of transcription factor NF-kappaB.

Kiichi Hirota;Miyahiko Murata;Yoshifumi Sachi;Hajime Nakamura

779
Citations
XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum

Rungtawan Sriburi;Suzanne Jackowski;Kazutoshi Mori;Joseph W. Brewer

748
Citations
Distinct roles of activating transcription factor 6 (ATF6) and double-stranded RNA-activated protein kinase-like endoplasmic reticulum kinase (PERK) in transcription during the mammalian unfolded protein response.

Tetsuya Okada;Hiderou Yoshida;Rieko Akazawa;Manabu Negishi

742
Citations
XBP1 Is Essential for Survival under Hypoxic Conditions and Is Required for Tumor Growth

Lorenzo Romero-Ramirez;Hongbin Cao;Daniel Nelson;Ester Hammond

690
Citations
Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis

Masahiro Shuda;Nobuo Kondoh;Nobuo Imazeki;Kenji Tanaka

614
Citations
cDNA cloning and regional distribution of a novel member of the opioid receptor family

Kazuhiko Fukuda;Shigehisa Kato;Kenjiro Mori;Miyuki Nishi

599
Citations
ATF6 is a transcription factor specializing in the regulation of quality control proteins in the endoplasmic reticulum.

Yusuke Adachi;Keisuke Yamamoto;Tetsuya Okada;Hiderou Yoshida

532
Citations
A 22 bp cis-acting element is necessary and sufficient for the induction of the yeast KAR2 (BiP) gene by unfolded proteins.

K Mori;A Sant;K Kohno;K Normington

513
Citations
Differential Contributions of ATF6 and XBP1 to the Activation of Endoplasmic Reticulum Stress-Responsive cis -Acting Elements ERSE, UPRE and ERSE-II

Keisuke Yamamoto;Hiderou Yoshida;Hiderou Yoshida;Koichi Kokame;Randal J. Kaufman

503
Citations