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Kazunori Imaizumi

Kazunori Imaizumi

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
15832
World Ranking
13616
National Ranking
953

Overview

Kazunori Imaizumi is a researcher affiliated with Hiroshima University in Japan, specializing in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans multiple areas within molecular and cellular biology, with a significant focus on genetics and disease mechanisms.

The scientist's research primarily covers the following main topics:

  • RNA Research and Splicing
  • Endoplasmic Reticulum Stress and Disease
  • Nuclear Structure and Function
  • RNA regulation and disease
  • Chronic Kidney Disease and Diabetes
  • Renal Diseases and Glomerulopathies
  • Ubiquitin and proteasome pathways

Their contributions include studies on molecular-level processes, especially those related to cellular stress responses and disease pathways involving ubiquitin ligases and transcription factors.

Recent published papers illustrate this broad investigative scope, including:

  • "The Role of Tissue-Specific Ubiquitin Ligases, RNF183, RNF186, RNF182 and RNF152, in Disease and Biological Function" (2020, International Journal of Molecular Sciences)
  • "OASIS/CREB3L1 is a factor that responds to nuclear envelope stress" (2021, Cell Death Discovery)
  • "Transcription factor old astrocyte specifically induced substance is a novel regulator of kidney fibrosis" (2020, The FASEB Journal)
  • "p53-independent tumor suppression by cell-cycle arrest via CREB/ATF transcription factor OASIS" (2023, Cell Reports)
  • "Loss of Function of Mutant IDS Due to Endoplasmic Reticulum-Associated Degradation: New Therapeutic Opportunities for Mucopolysaccharidosis Type II" (2021, International Journal of Molecular Sciences)

Imaizumi frequently publishes in venues oriented toward molecular and cellular biology and medicine. The main publication outlets include:

  • Proceedings for Annual Meeting of The Japanese Pharmacological Society
  • International Journal of Molecular Sciences
  • Cell Death Discovery
  • Journal of the American Society of Nephrology
  • The FASEB Journal

Collaboration is a notable aspect of their research activity. Frequent coauthors include:

  • Atsushi Saito
  • Yasunao Kamikawa
  • Masayuki Kaneko
  • Ayaha Yamamoto
  • Yoshiaki Miyake

The scientist's subfields of study reflect a concentration on molecular biology and its application to health and disease, encompassing:

  • Molecular Biology
  • Cell Biology
  • Nephrology
  • Genetics
  • Oncology

Best Publications

  • Autophagy Is Activated for Cell Survival after Endoplasmic Reticulum Stress

    Maiko Ogata;Shin Ichiro Hino;Atsushi Saito;Keisuke Morikawa

  • Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress.

    Takunari Yoneda;Kazunori Imaizumi;Kayoko Oono;Daishi Yui

  • Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Aβ-induced cell death

    Junichi Hitomi;Junichi Hitomi;Taiichi Katayama;Taiichi Katayama;Yutaka Eguchi;Yutaka Eguchi;Takashi Kudo

  • Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response

    Taiichi Katayama;Kazunori Imaizumi;Naoya Sato;Ko Miyoshi

  • Obesity-induced endoplasmic reticulum stress causes chronic inflammation in adipose tissue

    Noritaka Kawasaki;Rie Asada;Atsushi Saito;Soshi Kanemoto

  • Induction of neuronal death by ER stress in Alzheimer's disease.

    Taiichi Katayama;Kazunori Imaizumi;Takayuki Manabe;Junichi Hitomi

  • Angiotensin II Type 1a Receptor-deficient Mice with Hypotension and Hyperreninemia

    Takeshi Sugaya;Shin-ichiro Nishimatsu;Keiji Tanimoto;Eriko Takimoto

  • Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation.

    Tomohiko Murakami;Atsushi Saito;Shin Ichiro Hino;Shinichi Kondo

  • A molecular chaperone inducer protects neurons from ER stress

    T Kudo;S Kanemoto;S Kanemoto;H Hara;N Morimoto

  • Apoptosis induced by endoplasmic reticulum stress depends on activation of caspase-3 via caspase-12.

    Junichi Hitomi;Taiichi Katayama;Manabu Taniguchi;Akiko Honda

  • OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes

    Shinichi Kondo;Tomohiko Murakami;Tomohiko Murakami;Kouko Tatsumi;Maiko Ogata;Maiko Ogata

  • Endoplasmic Reticulum Stress Response Mediated by the PERK-eIF2α-ATF4 Pathway Is Involved in Osteoblast Differentiation Induced by BMP2

    Atsushi Saito;Kimiko Ochiai;Shinichi Kondo;Kenji Tsumagari

  • Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis.

    Atsushi Saito;Shin-ichiro Hino;Tomohiko Murakami;Soshi Kanemoto

  • Disturbed activation of endoplasmic reticulum stress transducers by familial Alzheimer's disease-linked presenilin-1 mutations.

    Taiichi Katayama;Kazunori Imaizumi;Akiko Honda;Takunari Yoneda

  • The signalling from endoplasmic reticulum-resident bZIP transcription factors involved in diverse cellular physiology.

    Rie Asada;Soshi Kanemoto;Shinichi Kondo;Atsushi Saito

  • BBF2H7, a novel transmembrane bZIP transcription factor, is a new type of endoplasmic reticulum stress transducer.

    Shinichi Kondo;Atsushi Saito;Shin Ichiro Hino;Tomohiko Murakami

  • Molecular Cloning of a Novel Polypeptide, DP5, Induced during Programmed Neuronal Death

    Kazunori Imaizumi;Manabu Tsuda;Yuji Imai;Akio Wanaka

  • The unfolded protein response and Alzheimer's disease.

    Kazunori Imaizumi;Ko Miyoshi;Taiichi Katayama;Takunari Yoneda

  • The human endogenous retrovirus envelope glycoprotein, syncytin-1, regulates neuroinflammation and its receptor expression in multiple sclerosis: a role for endoplasmic reticulum chaperones in astrocytes.

    Joseph M. Antony;Kristofor K. Ellestad;Robert Hammond;Kazunori Imaizumi

  • Expression of Zinc Transporter Gene, ZnT-1, Is Induced after Transient Forebrain Ischemia in the Gerbil

    Manabu Tsuda;Kazunori Imaizumi;Taiichi Katayama;Kazuo Kitagawa

Frequent Co-Authors

Masaya Tohyama
Masaya Tohyama Kindai University
Taiichi Katayama
Taiichi Katayama Osaka University
Masatoshi Takeda
Masatoshi Takeda Izumi University
Akio Wanaka
Akio Wanaka Nara Medical University
Hideaki Hara
Hideaki Hara Gifu Pharmaceutical University
Masamitsu Shimazawa
Masamitsu Shimazawa Gifu Pharmaceutical University
Riko Nishimura
Riko Nishimura Osaka University
Akila Mayeda
Akila Mayeda Fujita Health University
Fumihiko Urano
Fumihiko Urano Washington University in St. Louis

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