World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
9783
World Ranking
14570
National Ranking
1033

Overview

Akio Wanaka is affiliated with Nara Medical University in Japan. Their research primarily focuses on the fields of Neuroscience and Biochemistry, Genetics and Molecular Biology. Within these broader fields, Wanaka has contributed extensively to subfields including Cellular and Molecular Neuroscience, Neurology, Molecular Biology, Physiology, and Developmental Neuroscience.

The main research topics covered by Akio Wanaka involve mechanisms related to nerve injury and regeneration, neuroinflammation and neurodegeneration, pain mechanisms and treatments, neurogenesis and neuroplasticity, immune response and inflammation, circadian rhythm and melatonin, as well as neuroendocrine regulation and behavior.

Wanaka has published research in a range of scientific journals. The frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Immunology
  • PLoS ONE
  • Glia
  • Frontiers in Cellular Neuroscience

Their recent papers demonstrate a focus on molecular signaling pathways in the context of neuroinflammation and pain. Selected papers include:

  • "Dermal macrophages set pain sensitivity by modulating the amount of tissue NGF through an SNX25-Nrf2 pathway," 2023, Nature Immunology
  • "SNX25 regulates proinflammatory cytokine expression via the NF-κB signal in macrophages," 2021, PLoS ONE
  • "Large-scale electron microscopic volume imaging of interfascicular oligodendrocytes in the mouse corpus callosum," 2021, Glia
  • "Depletion of microglia and macrophages with clodronate liposomes attenuates zymosan-induced Fos expression and hypothermia in the adult mouse," 2020, Journal of Neuroimmunology
  • "Gene Expression Profiles of Human Cerebral Organoids Identify PPAR Pathway and PKM2 as Key Markers for Oxygen-Glucose Deprivation and Reoxygenation," 2021, Frontiers in Cellular Neuroscience

Coauthors frequently collaborating with Akio Wanaka include Tatsuhide Tanaka, Kouko Tatsumi, Ayami Isonishi, Shoko Takemura, and Hiroaki Okuda. Their collaboration counts range from 8 to 17 publications, indicating sustained joint research efforts.

Best Publications

  • Localization of FGF receptor mRNA in the adult rat central nervous system by in situ hybridization.

    Akio Wanaka;Eugene M. Johnson;Jeffrey Milbrand

  • Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation.

    Tomohiko Murakami;Atsushi Saito;Shin Ichiro Hino;Shinichi Kondo

  • OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes

    Shinichi Kondo;Tomohiko Murakami;Tomohiko Murakami;Kouko Tatsumi;Maiko Ogata;Maiko Ogata

  • Localization of ADAMTS13 to the stellate cells of human liver.

    Masahito Uemura;Kouko Tatsumi;Masanori Matsumoto;Masao Fujimoto

  • Expression of FGF receptor gene in rat development

    A. Wanaka;Jeffrey Milbrandt;E. M. Johnson

  • Localization of mRNA for c-kit receptor and its ligand in the brain of adult rats: an analysis using in situ hybridization histochemistry.

    Seiichi Hirota;Akihiko Ito;Eiichi Morii;Akio Wanaka

  • Localization and functional coupling of HGF and c-Met/HGF receptor in rat brain: implication as neurotrophic factor

    Shigeyuki Honda;Masako Kagoshima;Akio Wanaka;Masaya Tohyama

  • Molecular Cloning of a Novel Polypeptide, DP5, Induced during Programmed Neuronal Death

    Kazunori Imaizumi;Manabu Tsuda;Yuji Imai;Akio Wanaka

  • Localization of glycine receptors in the rat central nervous system: an immunocytochemical analysis using monoclonal antibody.

    T. Araki;M. Yamano;T. Murakami;A. Wanaka

  • Expression of Zinc Transporter Gene, ZnT-1, Is Induced after Transient Forebrain Ischemia in the Gerbil

    Manabu Tsuda;Kazunori Imaizumi;Taiichi Katayama;Kazuo Kitagawa

  • Cleavage of the membrane-bound transcription factor OASIS in response to endoplasmic reticulum stress.

    Tomohiko Murakami;Shinichi Kondo;Maiko Ogata;Maiko Ogata;Soshi Kanemoto;Soshi Kanemoto

  • Specific expressions of Fyn and Lyn, lymphocyte antigen receptor-associated tyrosine kinases, in the central nervous system.

    Hisashi Umemori;Akio Wanaka;Hidemasa Kato;Masakazu Takeuchi

  • Slit and glypican-1 mRNAs are coexpressed in the reactive astrocytes of the injured adult brain

    Seita Hagino;Ken Iseki;Tetsuji Mori;Yuxiang Zhang

  • Differential expression of two members of FGF receptor gene family, FGFR-1 and FGFR-2 mRNA, in the adult rat central nervous system

    Tatsuya Asai;Akio Wanaka;Hidemasa Kato;Yoshiyuki Masana

  • Maternal immune activation in mice delays myelination and axonal development in the hippocampus of the offspring.

    Manabu Makinodan;Kouko Tatsumi;Takayuki Manabe;Takahira Yamauchi

  • Differential expression of sgk mRNA, a member of the Ser/Thr protein kinase gene family, in rat brain after CNS injury.

    K. Imaizumi;M. Tsuda;A. Wanaka;M. Tohyama

  • The Cell Death-promoting Gene DP5, Which Interacts with the BCL2 Family, Is Induced during Neuronal Apoptosis Following Exposure to Amyloid β Protein

    Kazunori Imaizumi;Takashi Morihara;Yasutake Mori;Taiichi Katayama

  • Localization of trkB mRNA in postnatal brain development.

    Y. Masana;A. Wanaka;H. Kato;T. Asai

  • Localization of Fas antigen mRNA induced in postischemic murine forebrain by in situ hybridization

    Tomohiro Matsuyama;Ryuji Hata;Yoshihiro Yamamoto;Masafumi Tagaya

  • Genetic fate mapping of Olig2 progenitors in the injured adult cerebral cortex reveals preferential differentiation into astrocytes

    Kouko Tatsumi;Hirohide Takebayashi;Takayuki Manabe;Kenji F. Tanaka

Frequent Co-Authors

Masaya Tohyama
Masaya Tohyama Kindai University
Kazunori Imaizumi
Kazunori Imaizumi Hiroshima University
Takenobu Kamada
Takenobu Kamada Osaka University
Tomohiro Matsuyama
Tomohiro Matsuyama Hyogo College of Medicine
Masayasu Matsumoto
Masayasu Matsumoto Hiroshima University
Hiroshi Kiyama
Hiroshi Kiyama Nagoya University
Craig C. Malbon
Craig C. Malbon Stony Brook University
Heinrich Betz
Heinrich Betz Max Planck Society
Takashi Muramatsu
Takashi Muramatsu Nagoya University
Sadao Shiosaka
Sadao Shiosaka Osaka University

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