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Hiroshi Kiyama

Hiroshi Kiyama

D-Index & Metrics

Biology and Biochemistry

D-Index
74
Citations
19990
World Ranking
5591
National Ranking
360

Overview

Hiroshi Kiyama is affiliated with Nagoya University in Japan, specializing in the fields of Medicine and Neuroscience. The primary areas of research encompass Neurology, Cellular and Molecular Neuroscience, Immunology, Molecular Biology, and Surgery. Their research topics include Neuroinflammation and Neurodegeneration Mechanisms, Nerve Injury and Regeneration, Immune Cells in Cancer, Neurogenesis and Neuroplasticity Mechanisms, Cardiac Valve Diseases and Treatments, Barrier Structure and Function Studies, and Amyotrophic Lateral Sclerosis Research.

Kiyama has published extensively in several academic venues, with recurring contributions to The EMBO Journal and Glia. The scientist also has publications in Cell and Tissue Research, Neurochemistry International, and Cell Death and Disease.

Recent research papers include the following:

  • Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction (2020, The EMBO Journal)
  • Phagocytic astrocytes: Emerging from the shadows of microglia (2022, Glia)
  • Non-pathological roles of microglial TREM2/DAP12: TREM2/DAP12 regulates the physiological functions of microglia from development to aging (2020, Neurochemistry International)
  • Impaired disassembly of the axon initial segment restricts mitochondrial entry into damaged axons (2022, The EMBO Journal)
  • Correction: Damage-induced neuronal endopeptidase (DINE) enhances axonal regeneration potential of retinal ganglion cells after optic nerve injury (2020, Cell Death and Disease)

Kiyama's research is frequently conducted in collaboration with several co-authors, the most frequent being Sumiko Kiryu-Seo, Hiroyuki Konishi, Hiromi Tamada, Taiyo Jinno, and Hidetaka Yamauchi.

Best Publications

  • Dual microglia effects on blood brain barrier permeability induced by systemic inflammation.

    Koichiro Haruwaka;Koichiro Haruwaka;Ako Ikegami;Yoshihisa Tachibana;Nobuhiko Ohno

  • mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells.

    Mirei Murakami;Tomoko Ichisaka;Tomoko Ichisaka;Mitsuyo Maeda;Noriko Oshiro;Noriko Oshiro

  • Ubiquitin carboxy-terminal hydrolase L1 binds to and stabilizes monoubiquitin in neuron

    Hitoshi Osaka;Yu Lai Wang;Koji Takada;Shuichi Takizawa

  • Coexistence of calcitonin gene-related peptide and substance P-like peptide in single cells of the trigeminal ganglion of the rat: immunohistochemical analysis.

    Y. Lee;Y. Kawai;S. Shiosaka;K. Takami

  • Accelerated Nerve Regeneration in Mice by upregulated expression of interleukin (IL) 6 and IL-6 receptor after trauma.

    H Hirota;H Kiyama;T Kishimoto;T Taga

  • Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases.

    Keiro Shirotani;Satoshi Tsubuki;Nobuhisa Iwata;Yoshie Takaki

  • The differential expression patterns of messenger RNAs encoding non-N-methyl-d-aspartate glutamate receptor subunits (GluR1–4) in the rat brain

    K. Sato;H. Kiyama;M. Tohyama

  • Vascular endothelial growth factor rescues hippocampal neurons from glutamate-induced toxicity: signal transduction cascades

    Hideo Matsuzaki;Michio Tamatani;Atsushi Yamaguchi;Kazuhiko Namikawa

  • Akt/Protein Kinase B Prevents Injury-Induced Motoneuron Death and Accelerates Axonal Regeneration

    Kazuhiko Namikawa;Masaru Honma;Koji Abe;Masumi Takeda

  • Expression of the Activating Transcription Factor 3 Prevents c-Jun N-Terminal Kinase-Induced Neuronal Death by Promoting Heat Shock Protein 27 Expression and Akt Activation

    Saya Nakagomi;Yasuhiro Suzuki;Kazuhiko Namikawa;Sumiko Kiryu-Seo

  • Akt Activation Protects Hippocampal Neurons from Apoptosis by Inhibiting Transcriptional Activity of p53

    Atsushi Yamaguchi;Michio Tamatani;Hideo Matsuzaki;Kazuhiko Namikawa

  • A Novel ATP-dependent Inward Rectifier Potassium Channel Expressed Predominantly in Glial Cells

    Toru Takumi;Takahiro Ishii;Yoshiyuki Horio;Ken-Ichirou Morishige

  • Activation of Akt kinase inhibits apoptosis and changes in Bcl-2 and Bax expression induced by nitric oxide in primary hippocampal neurons.

    H. Matsuzaki;M. Tamatani;N. Mitsuda;K. Namikawa

  • Microglial TREM2/DAP12 Signaling: A Double-Edged Sword in Neural Diseases.

    Hiroyuki Konishi;Hiroshi Kiyama

  • Expression and activity-dependent changes of a novel limbic-serine protease gene in the hippocampus

    ZL Chen;S Yoshida;K Kato;Y Momota

  • AMPA, KA and NMDA receptors are expressed in the rat DRG neurones.

    Kohji Sato;Hiroshi Kiyama;Hwan Tae Park;Masaya Tohyama

  • Localization of oxytocin receptor messenger ribonucleic acid in the rat brain

    Ryoichi Yoshimura;Hiroshi Kiyama;Tadashi Kimura;Toshiyuki Araki

  • Distribution of the substance P receptor (NK-1 receptor) in the central nervous system

    Hiroshi Maeno;Hiroshi Kiyama;Masaya Tohyama

  • A noxious stimulus induces the preprotachykinin-A gene expression in the rat dorsal root ganglion: a quantitative study using in situ hybridization histochemistry

    Koichi Noguchi;Yasuhiro Morita;Hiroshi Kiyama;Keiro Ono

  • Region-specific expression of subunits of ionotropic glutamate receptors (AMPA-type, KA-type and NMDA receptors) in the rat spinal cord with special reference to nociception

    Tatsuo Furuyama;Hiroshi Kiyama;Kohji Sato;Hwan Tae Park

Frequent Co-Authors

Masaya Tohyama
Masaya Tohyama Kindai University
Makoto Sato
Makoto Sato University of Fukui
Piers C. Emson
Piers C. Emson Babraham Institute
Sadao Shiosaka
Sadao Shiosaka Osaka University
Takeshi Kubo
Takeshi Kubo Osaka University
Kohji Sato
Kohji Sato Hamamatsu University
Akio Wanaka
Akio Wanaka Nara Medical University
Makoto Tsuda
Makoto Tsuda Kyushu University
Yasuyoshi Watanabe
Yasuyoshi Watanabe Osaka Metropolitan University
Yoshiyuki Horio
Yoshiyuki Horio Sapporo Medical University

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