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Neuroscience

D-Index
85
Citations
20060
World Ranking
1358
National Ranking
682

Research.com Recognitions

  • 1983 - Fellow of Alfred P. Sloan Foundation

Overview

Nicholas C. Brecha is affiliated with the University of California, Los Angeles in the United States. Their research primarily focuses on neuroscience and biochemistry, genetics, and molecular biology, with notable specialization in molecular biology and cellular and molecular neuroscience. Additional areas of study include cognitive neuroscience, endocrine and autonomic systems, and neurology.

The scientist has contributed extensively to topics such as retinal development and disorders, photoreceptor and optogenetics research, neuroscience and neuropharmacology research, neuroinflammation and neurodegeneration mechanisms, single-cell and spatial transcriptomics, cell image analysis techniques, and mitochondrial function and pathology.

Brecha's published works include the following recent papers:

  • Brainwide Genetic Sparse Cell Labeling to Illuminate the Morphology of Neurons and Glia with Cre-Dependent MORF Mice, 2020, Neuron
  • Horizontal Cell Feedback to Cone Photoreceptors in Mammalian Retina: Novel Insights From the GABA-pH Hybrid Model, 2020, Frontiers in Cellular Neuroscience
  • Vesicular Release of GABA by Mammalian Horizontal Cells Mediates Inhibitory Output to Photoreceptors, 2020, Frontiers in Cellular Neuroscience
  • LKB1 coordinates neurite remodeling to drive synapse layer emergence in the outer retina, 2020, eLife
  • Transient and Sustained Ganglion Cell Light Responses Are Differentially Modulated by Intrinsically Produced Reactive Oxygen Species Acting upon Specific Voltage-Gated Na+ Channel Isoforms, 2023, Journal of Neuroscience

Frequent co-authors in Brecha's research include:

  • Arlene A. Hirano (7 collaborations)
  • Steven Barnes (3 collaborations)
  • Luis Pérez de Sevilla Müller (3 collaborations)
  • Elizabeth Zuniga-Sanchez (2 collaborations)
  • Cyrus F. McHugh (2 collaborations)

Common venues for publishing Brecha's research consist of:

  • Frontiers in Cellular Neuroscience
  • Neuron
  • eLife
  • Journal of Neuroscience
  • Frontiers in Neuroanatomy

In 1983, Nicholas C. Brecha was recognized as a Fellow of the Alfred P. Sloan Foundation.

Best Publications

  • A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter.

    Yongjian Liu;Doris Peter;Ali Roghani;Shimon Schuldiner

  • Immunocytochemical localization of vasoactive intestinal polypeptide- containing cells and processes in the suprachiasmatic nucleus of the rat: light and electron microscopic analysis

    JP Card;N Brecha;HJ Karten;RY Moore

  • The RNA binding protein RBPMS is a selective marker of ganglion cells in the mammalian retina.

    Allen R. Rodriguez;Luis Pérez de Sevilla Müller;Nicholas C. Brecha

  • Localization of enkephalin-like immunoreactivity to identified axonal and neuronal populations of the rat hippocampus

    Christine Gall;Nicholas Brecha;H. J. Karten;Kwen-Jen Chang

  • Distribution and characterization of calcitonin gene-related peptide immunoreactivity in the digestive system of normal and capsaicin-treated rats

    C. Sternini;J.R. Reeve;N. Brecha

  • Differential expression of two vesicular monoamine transporters

    D Peter;Y Liu;C Sternini;R de Giorgio

  • Agonist-selective endocytosis of mu opioid receptor by neurons in vivo.

    C Sternini;M Spann;B Anton;D E Keith

  • GAT-1, A HIGH-AFFINITY GABA PLASMA MEMBRANE TRANSPORTER, IS LOCALIZED TO NEURONS AND ASTROGLIA IN THE CEREBRAL CORTEX

    A Minelli;NC Brecha;C Karschin;S DeBiasi

  • Cloning, expression, and localization of a rat brain high-affinity glycine transporter.

    John Guastella;Nicholas Brecha;Christine Weigmann;Henry A. Lester

  • Peripheral patterns of calcitonin-gene-related peptide general somatic sensory innervation: Cutaneous and deep terminations

    Lawrence Kruger;James D. Silverman;Patrick W. Mantyh;Catia Sternini

  • A novel α subunit in rat brain GABAA receptors

    Michel Khrestchatisky;A.John MacLennan;Ming-Yi Chiang;Wentao Xu

  • GAT-3, a High-Affinity GABA Plasma Membrane Transporter, Is Localized to Astrocytic Processes, and It Is Not Confined to the Vicinity of GABAergic Synapses in the Cerebral Cortex

    Andrea Minelli;Silvia DeBiasi;Nicholas C. Brecha;Laura Vitellaro Zuccarello

  • Cholinergic amacrine cells of the rabbit retina contain glutamate decarboxylase and gamma-aminobutyrate immunoreactivity.

    Nicholas Brecha;Donald Johnson;Leo Peichl;Heinz Wassle

  • GABA plasma membrane transporters, GAT-1 and GAT-3, display different distributions in the rat hippocampus.

    Charles E. Ribak;Winnie M.Y. Tong;Nicholas C. Brecha;Nicholas C. Brecha

  • The morphology and distribution of peptide-containing neurons in the adult and developing visual cortex of the rat. III. Cholecystokinin.

    John K. McDonald;John G. Parnavelas;Azarias N. Karamanlidis;Grace Rosenquist

  • Calcitonin gene-related peptide (CGRP) in the rat central nervous system: patterns of immunoreactivity and receptor binding sites

    Lawrence Kruger;Patrick W. Mantyh;Catia Sternini;Nicholas C. Brecha

  • Projections of the nucleus of the basal optic root in the pigeon: an autoradiographic and horseradish peroxidase study.

    Nicholas Brecha;H. J. Karten;S. P. Hunt

  • Protein kinase C modulates the activity of a cloned gamma-aminobutyric acid transporter expressed in Xenopus oocytes via regulated subcellular redistribution of the transporter.

    Janis L. Corey;Norman Davidson;Henry A. Lester;Nicholas Brecha

  • Spine loss and regrowth in hippocampus following deafferentation.

    John G. Parnavelas;G. Lynch;N. Brecha;C. W. Cotman

  • Molecular cloning of a putative vesicular transporter for acetylcholine

    Ali Roghani;Jonathan Feldman;Sirus A. Kohan;Arshia Shirzadi

Frequent Co-Authors

Catia Sternini
Catia Sternini University of California, Los Angeles
Harvey J. Karten
Harvey J. Karten University of California, San Diego
Steven Barnes
Steven Barnes University of California, Los Angeles
Fiorenzo Conti
Fiorenzo Conti Marche Polytechnic University
Johann Helmut Brandstätter
Johann Helmut Brandstätter University of Erlangen-Nuremberg
Patrick W. Mantyh
Patrick W. Mantyh University of Arizona
Myung-Hoon Chun
Myung-Hoon Chun Catholic University of Korea
Robert H. Edwards
Robert H. Edwards University of California, San Francisco
Christine M. Gall
Christine M. Gall University of California, Irvine
Nicolás Cuenca
Nicolás Cuenca University of Alicante

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