D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Neuroscience D-index 69 Citations 13,429 193 World Ranking 1544 National Ranking 762

Research.com Recognitions

Awards & Achievements

1983 - Fellow of Alfred P. Sloan Foundation

Overview

What is he best known for?

The fields of study he is best known for:

  • Neurotransmitter
  • Neuron
  • Internal medicine

The scientist’s investigation covers issues in Endocrinology, Internal medicine, Cell biology, Retina and Molecular biology. The concepts of his Endocrinology study are interwoven with issues in Myenteric plexus, Calcitonin gene-related peptide and Peptide. His research in Internal medicine intersects with topics in Golgi apparatus and Developmental biology.

Nicholas C. Brecha has included themes like Opiate alkaloid, Dopaminergic, Receptor, Biochemistry and Substance P in his Cell biology study. Many of his studies on Retina involve topics that are commonly interrelated, such as Voltage-dependent calcium channel. His Molecular biology research includes elements of In situ hybridization, Northern blot, GABAA receptor, Glycine Plasma Membrane Transport Proteins and Synaptic vesicle.

His most cited work include:

  • A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter. (545 citations)
  • Agonist-selective endocytosis of mu opioid receptor by neurons in vivo. (297 citations)
  • Agonist-selective endocytosis of mu opioid receptor by neurons in vivo. (297 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Retina, Cell biology, Internal medicine, Endocrinology and Neuroscience. His work in Retina addresses issues such as Anatomy, which are connected to fields such as Biophysics and Nucleus. Nicholas C. Brecha combines subjects such as Cell, Biochemistry, Voltage-dependent calcium channel, Retinal ganglion and Synaptic vesicle with his study of Cell biology.

His research investigates the connection between Endocrinology and topics such as Enkephalin that intersect with issues in Opioid peptide. His Inner plexiform layer study also includes

  • Outer plexiform layer that intertwine with fields like Immunostaining,
  • Cellular localization which is related to area like Cerebral cortex. His studies deal with areas such as Molecular biology, Nervous system and Tyrosine hydroxylase as well as Inner nuclear layer.

He most often published in these fields:

  • Retina (60.36%)
  • Cell biology (50.00%)
  • Internal medicine (35.00%)

What were the highlights of his more recent work (between 2012-2021)?

  • Cell biology (50.00%)
  • Retina (60.36%)
  • Neuroscience (34.29%)

In recent papers he was focusing on the following fields of study:

Cell biology, Retina, Neuroscience, Voltage-dependent calcium channel and Retinal ganglion are his primary areas of study. Particularly relevant to Axon is his body of work in Cell biology. His Retina research integrates issues from Molecular biology, Retinal and Anatomy, Optic nerve.

His work on Receptive field, GABAergic and Synapse as part of general Neuroscience study is frequently connected to Microglia, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. Ganglion cell layer is closely connected to Inner nuclear layer in his research, which is encompassed under the umbrella topic of Amacrine cell. While the research belongs to areas of Patch clamp, Nicholas C. Brecha spends his time largely on the problem of Pharmacology, intersecting his research to questions surrounding Internal medicine, Endocrinology, MAPK/ERK pathway, Opioid and DAMGO.

Between 2012 and 2021, his most popular works were:

  • The RNA binding protein RBPMS is a selective marker of ganglion cells in the mammalian retina. (236 citations)
  • Activation of the Nrf2/HO-1 Antioxidant Pathway Contributes to the Protective Effects of Lycium Barbarum Polysaccharides in the Rodent Retina after Ischemia-Reperfusion-Induced Damage (121 citations)
  • Calcium channels in rat horizontal cells regulate feedback inhibition of photoreceptors through an unconventional GABA- and pH-sensitive mechanism. (57 citations)

In his most recent research, the most cited papers focused on:

  • Neurotransmitter
  • Neuron
  • Internal medicine

His primary areas of investigation include Retina, Neuroscience, Cell biology, Inhibitory postsynaptic potential and Voltage-dependent calcium channel. His Cell biology research is multidisciplinary, incorporating perspectives in Axotomy and Calcium channel. His Inhibitory postsynaptic potential research is multidisciplinary, relying on both Kainate receptor, Synaptic vesicle and Neurotransmission.

His Voltage-dependent calcium channel research is multidisciplinary, incorporating elements of Receptor, Dopamine and Dopamine receptor D1. As part of the same scientific family, Nicholas C. Brecha usually focuses on Amacrine cell, concentrating on RBPMS and intersecting with Ganglion cell layer. His work in Pharmacology covers topics such as Opioid receptor which are related to areas like Endocrinology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter.

Yongjian Liu;Doris Peter;Ali Roghani;Shimon Schuldiner.
Cell (1992)

729 Citations

Differential expression of two vesicular monoamine transporters

D Peter;Y Liu;C Sternini;R de Giorgio.
The Journal of Neuroscience (1995)

388 Citations

Agonist-selective endocytosis of mu opioid receptor by neurons in vivo.

C Sternini;M Spann;B Anton;D E Keith.
Proceedings of the National Academy of Sciences of the United States of America (1996)

388 Citations

GAT-1, A HIGH-AFFINITY GABA PLASMA MEMBRANE TRANSPORTER, IS LOCALIZED TO NEURONS AND ASTROGLIA IN THE CEREBRAL CORTEX

A Minelli;NC Brecha;C Karschin;S DeBiasi.
The Journal of Neuroscience (1995)

358 Citations

Cloning, expression, and localization of a rat brain high-affinity glycine transporter.

John Guastella;Nicholas Brecha;Christine Weigmann;Henry A. Lester.
Proceedings of the National Academy of Sciences of the United States of America (1992)

344 Citations

The RNA binding protein RBPMS is a selective marker of ganglion cells in the mammalian retina.

Allen R. Rodriguez;Luis Pérez de Sevilla Müller;Nicholas C. Brecha.
The Journal of Comparative Neurology (2014)

331 Citations

A novel α subunit in rat brain GABAA receptors

Michel Khrestchatisky;A.John MacLennan;Ming-Yi Chiang;Wentao Xu.
Neuron (1989)

330 Citations

Cholinergic amacrine cells of the rabbit retina contain glutamate decarboxylase and gamma-aminobutyrate immunoreactivity.

Nicholas Brecha;Donald Johnson;Leo Peichl;Heinz Wassle.
Proceedings of the National Academy of Sciences of the United States of America (1988)

311 Citations

The morphology and distribution of peptide-containing neurons in the adult and developing visual cortex of the rat. III. Cholecystokinin.

John K. McDonald;John G. Parnavelas;Azarias N. Karamanlidis;Grace Rosenquist.
Journal of Neurocytology (1982)

310 Citations

Calcitonin gene-related peptide (CGRP) in the rat central nervous system: patterns of immunoreactivity and receptor binding sites

Lawrence Kruger;Patrick W. Mantyh;Catia Sternini;Nicholas C. Brecha.
Brain Research (1988)

304 Citations

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