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Neuroscience

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114
Citations
38965
World Ranking
475
National Ranking
277

Medicine

D-Index
114
Citations
38949
World Ranking
4803
National Ranking
2607

Research.com Recognitions

  • 1985 - Fellow of Alfred P. Sloan Foundation

Overview

Patrick W. Mantyh is affiliated with the University of Arizona in the United States. Their research encompasses multiple areas within medicine and neuroscience, with a particular focus on pain mechanisms and treatments.

Their scholarly work includes contributions across various topics such as:

  • Pain Mechanisms and Treatments
  • Nerve Injury and Regeneration
  • Neuropeptides and Animal Physiology
  • Inflammatory Mediators and NSAID Effects
  • Pharmacological Effects of Natural Compounds
  • Pain Management and Opioid Use
  • Anesthesia and Pain Management

Mantyh's research fields are primarily in medicine and neuroscience, with subfields spanning:

  • Cellular and Molecular Neuroscience
  • Physiology
  • Pharmacology
  • Anesthesiology and Pain Medicine
  • Surgery

Several of Mantyh's recent publications demonstrate a focus on pain and therapeutic approaches:

  • "<p>Nerve Growth Factor Signaling and Its Contribution to Pain</p>", 2020, Journal of Pain Research
  • "Treating osteoarthritis pain: mechanisms of action of acetaminophen, nonsteroidal anti-inflammatory drugs, opioids, and nerve growth factor antibodies", 2021, Postgraduate Medicine
  • "Role of Neuraxial Drug Delivery in Cancer Pain Therapy", 2020, Future Drug Discovery

Frequent collaborators include:

  • Lars Viktrup
  • Tony L. Yaksh
  • Philip A. Barker
  • Lars Arendt-Nielsen
  • Leslie Tive

Mantyh's work has appeared in journals such as:

  • Journal of Pain Research
  • Postgraduate Medicine
  • Future Drug Discovery

In recognition of their career, Mantyh was named a Fellow of the Alfred P. Sloan Foundation in 1985.

Best Publications

  • The Cerebral Signature for Pain Perception and Its Modulation

    Irene Tracey;Patrick W. Mantyh

  • The molecular dynamics of pain control.

    Stephen P. Hunt;Patrick W. Mantyh

  • Origins of skeletal pain: sensory and sympathetic innervation of the mouse femur

    D. B. Mach;S. D. Rogers;S. D. Rogers;M. C. Sabino;M. C. Sabino;N. M. Luger;N. M. Luger

  • Primary afferent tachykinins are required to experience moderate to intense pain

    Yu Qing Cao;Patrick W. Mantyh;Elaine J. Carlson;Anne Marie Gillespie

  • Inhibition of hyperalgesia by ablation of lamina I spinal neurons expressing the substance P receptor.

    Patrick W. Mantyh;Scott D. Rogers;Scott D. Rogers;Prisca Honore;Prisca Honore;Brian J. Allen;Brian J. Allen

  • Neurochemical and cellular reorganization of the spinal cord in a murine model of bone cancer pain

    Matthew J. Schwei;Prisca Honore;Scott D. Rogers;Janeen L. Salak-Johnson

  • Murine models of inflammatory, neuropathic and cancer pain each generates a unique set of neurochemical changes in the spinal cord and sensory neurons.

    P Honore;S.D Rogers;M.J Schwei;J.L Salak-Johnson

  • Aluminum, Iron, and Zinc Ions Promote Aggregation of Physiological Concentrations of β‐Amyloid Peptide

    Patrick W. Mantyh;Joseph R. Ghilardi;Scott Rogers;Eric DeMaster

  • Osteoprotegerin blocks bone cancer-induced skeletal destruction, skeletal pain and pain-related neurochemical reorganization of the spinal cord

    Prisca Honore;Nancy M. Luger;Nancy M. Luger;Mary Ann C. Sabino;Mary Ann C. Sabino;Matthew J. Schwei;Matthew J. Schwei

  • Molecular mechanisms of cancer pain

    Patrick W. Mantyh;Denis R. Clohisy;Martin Koltzenburg;Steve P. Hunt

  • NMDA-receptor regulation of substance P release from primary afferent nociceptors

    Hantao Liu;Patrick W. Mantyh;Allan I. Basbaum

  • Diversity in mammalian tachykinin peptidergic neurons: multiple peptides, receptors, and regulatory mechanisms.

    C J Helke;J E Krause;P W Mantyh;R Couture

  • Receptor endocytosis and dendrite reshaping in spinal neurons after somatosensory stimulation

    Patrick W. Mantyh;Patrick W. Mantyh;Eric Demaster;Eric Demaster;Amit Malhotra;Joseph R. Ghilardi;Joseph R. Ghilardi

  • Transmission of chronic nociception by spinal neurons expressing the substance P receptor.

    Michael L. Nichols;Michael L. Nichols;Brian J. Allen;Brian J. Allen;Scott D. Rogers;Scott D. Rogers;Joseph R. Ghilardi;Joseph R. Ghilardi

  • Cancer pain and its impact on diagnosis, survival and quality of life

    Patrick W. Mantyh;Patrick W. Mantyh

  • Fibrillar β-Amyloid Induces Microglial Phagocytosis, Expression of Inducible Nitric Oxide Synthase, and Loss of a Select Population of Neurons in the Rat CNS In Vivo

    Derik T. Weldon;Scott D. Rogers;Joseph R. Ghilardi;Matthew P. Finke

  • Selective Blockade of the Capsaicin Receptor TRPV1 Attenuates Bone Cancer Pain

    Joseph R. Ghilardi;Heidi Röhrich;Theodore H. Lindsay;Molly A. Sevcik

  • Connections of midbrain periaqueductal gray in the monkey. I. Ascending efferent projections.

    P. W. Mantyh

  • Receptor binding sites for substance P, but not substance K or neuromedin K, are expressed in high concentrations by arterioles, venules, and lymph nodules in surgical specimens obtained from patients with ulcerative colitis and Crohn disease.

    Christopher R. Mantyh;Troy S. Gates;Robert P. Zimmerman;Mark L. Welton

  • Rapid endocytosis of a G protein-coupled receptor: substance P evoked internalization of its receptor in the rat striatum in vivo.

    Patrick W. Mantyh;Clark J. Allen;Joseph R. Ghilardi;Scott D. Rogers

Frequent Co-Authors

Joseph R. Ghilardi
Joseph R. Ghilardi ThreeWire, Inc.
Scott D. Rogers
Scott D. Rogers University of Minnesota
Michael A. Kuskowski
Michael A. Kuskowski University of Minnesota
Prisca Honore
Prisca Honore University of Minnesota
Allan I. Basbaum
Allan I. Basbaum University of California, San Francisco
Donald A. Simone
Donald A. Simone University of Minnesota
Tony L. Yaksh
Tony L. Yaksh University of California, San Diego
Michel Goedert
Michel Goedert MRC Laboratory of Molecular Biology
Todd W. Vanderah
Todd W. Vanderah University of Arizona
Harry V. Vinters
Harry V. Vinters University of California, Los Angeles

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