Donald A. Simone

Overview

Best Publications

• Neurogenic hyperalgesia: psychophysical studies of underlying mechanisms.

  R. H. LaMotte;C. N. Shain;Donald A Simone;E. F.P. Tsai

  1160
  Citations

• Neurogenic hyperalgesia: central neural correlates in responses of spinothalamic tract neurons

  D. A. Simone;L. S. Sorkin;U. Oh;J. M. Chung

  739
  Citations

• Inhibition of hyperalgesia by ablation of lamina I spinal neurons expressing the substance P receptor.

  Patrick W. Mantyh;Scott D. Rogers;Scott D. Rogers;Prisca Honore;Prisca Honore;Brian J. Allen;Brian J. Allen

  735
  Citations

• Dose-dependent pain and mechanical hyperalgesia in humans after intradermal injection of capsaicin.

  Donald A. Simone;Thomas K. Baumann;Robert H. LaMotte

  585
  Citations

• Topical capsaicin in humans: parallel loss of epidermal nerve fibers and pain sensation.

  Maria Nolano;Donald A. Simone;Gwen Wendelschafer-Crabb;Timothy Johnson

  582
  Citations

• Receptor endocytosis and dendrite reshaping in spinal neurons after somatosensory stimulation

  Patrick W. Mantyh;Patrick W. Mantyh;Eric Demaster;Eric Demaster;Amit Malhotra;Joseph R. Ghilardi;Joseph R. Ghilardi

  537
  Citations

• Neurogenic hyperalgesia: the search for the primary cutaneous afferent fibers that contribute to capsaicin-induced pain and hyperalgesia.

  T. K. Baumann;D. A. Simone;C. N. Shain;R. H. LaMotte

  536
  Citations

• Transmission of chronic nociception by spinal neurons expressing the substance P receptor.

  Michael L. Nichols;Michael L. Nichols;Brian J. Allen;Brian J. Allen;Scott D. Rogers;Scott D. Rogers;Joseph R. Ghilardi;Joseph R. Ghilardi

  526
  Citations

• Windup leads to characteristics of central sensitization

  Jun Li;Donald A Simone;Alice A Larson

  442
  Citations

• Intradermal Injection of Capsaicin in Humans Produces Degeneration and Subsequent Reinnervation of Epidermal Nerve Fibers: Correlation with Sensory Function

  Donald A. Simone;Maria Nolano;Timothy Johnson;Gwen Wendelschafer-Crabb

  420
  Citations

• The itch-producing agents histamine and cowhage activate separate populations of primate spinothalamic tract neurons.

  Steve Davidson;Xijing Zhang;Chul H. Yoon;Sergey G. Khasabov

  309
  Citations

• Response properties of mechanoreceptors and nociceptors in mouse glabrous skin: an in vivo study.

  David M. Cain;Sergey G. Khasabov;Donald A. Simone

  300
  Citations

• Spinal neurons that possess the substance P receptor are required for the development of central sensitization.

  Sergey G. Khasabov;Scott D. Rogers;Joseph R. Ghilardi;Christopher M. Peters

  295
  Citations

• Enhanced withdrawal responses to heat and mechanical stimuli following intraplantar injection of capsaicin in rats.

  Hart D. Gilchrist;Brandon L. Allard;Donald A. Simone

  279
  Citations

• Responses of cutaneous A-fiber nociceptors to noxious cold.

  Donald A. Simone;Keith C. Kajander

  254
  Citations

• Mast cell activation contributes to sickle cell pathobiology and pain in mice.

  Lucile Vincent;Derek Vang;Julia Nguyen;Mihir Gupta

  249
  Citations

• A randomized, controlled, open-label study of the long-term effects of NGX-4010, a high-concentration capsaicin patch, on epidermal nerve fiber density and sensory function in healthy volunteers.

  William R. Kennedy;Geertrui F. Vanhove;Shiao ping Lu;Jeffrey Tobias

  246
  Citations

• Psychophysical studies of the itch sensation and itchy skin ("alloknesis") produced by intracutaneous injection of histamine.

  Donald A. Simone;Meenakshi Alreja;Robert H. Lamotte

  231
  Citations

• Mechanism of cancer pain.

  Brian L. Schmidt;Darryl T. Hamamoto;Donald A. Simone;George L. Wilcox

  227
  Citations

• Identification of muscle afferents subserving sensation of deep pain in humans

  Donald A Simone;P. Marchettini;G. Caputi;J. L. Ochoa

  225
  Citations

• Pain from excitation of identified muscle nociceptors in humans

  Paolo Marchettini;Donald A. Simone;Graziella Caputi;José L. Ochoa

  219
  Citations