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Biology and Biochemistry

D-Index
116
Citations
89362
World Ranking
735
National Ranking
467

Medicine

D-Index
116
Citations
89381
World Ranking
4251
National Ranking
2326

Research.com Recognitions

  • 2020 - Member of the National Academy of Medicine (NAM)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Ralph J. DeBerardinis is affiliated with The University of Texas Southwestern Medical Center in the United States. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, with a significant focus on Medicine. Within these domains, their work addresses specialized subfields such as Molecular Biology, Cancer Research, Oncology, Immunology, and Genetics.

The principal topics of DeBerardinis's research include:

  • Cancer, Hypoxia, and Metabolism
  • Mitochondrial Function and Pathology
  • RNA Modifications and Cancer
  • Epigenetics and DNA Methylation
  • Metabolomics and Mass Spectrometry Studies
  • Metabolism and Genetic Disorders
  • Biochemical and Molecular Research

DeBerardinis has published extensively in several scientific journals. The most frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Science Advances
  • Nature Metabolism
  • Science

Among recent papers, the following are notable:

  • "Metabolic reprogramming and cancer progression," 2020, Science
  • "We need to talk about the Warburg effect," 2020, Nature Metabolism
  • "Mechanical regulation of glycolysis via cytoskeleton architecture," 2020, Nature
  • "Apoptotic cell death in disease-Current understanding of the NCCD 2023," 2023, Cell Death and Differentiation
  • "Tumor Microenvironment, Metabolism, and Immunotherapy," 2020, New England Journal of Medicine

Their frequent collaborators include:

  • Lauren G. Zacharias
  • Feng Cai
  • Hieu Vu
  • Ling Cai
  • Brandon Faubert

Ralph J. DeBerardinis has been recognized with the following awards:

  • Member of the National Academy of Medicine (NAM), 2020
  • Member of the Association of American Physicians

Best Publications

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • THE BIOLOGY OF CANCER: METABOLIC REPROGRAMMING FUELS CELL GROWTH AND PROLIFERATION

    Ralph J. DeBerardinis;Julian J. Lum;Georgia Hatzivassiliou;Craig B. Thompson

  • Beyond aerobic glycolysis : Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

    Ralph J. DeBerardinis;Anthony Mancuso;Evgueni Daikhin;Ilana Nissim

  • Fundamentals of cancer metabolism

    Ralph J. DeBerardinis;Navdeep S. Chandel

  • Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

    David R. Wise;Ralph J. Deberardinis;Anthony Mancuso;Nabil Sayed

  • Understanding the Intersections between Metabolism and Cancer Biology

    Matthew G. Vander Heiden;Matthew G. Vander Heiden;Ralph J. DeBerardinis

  • Toll-like Receptor-Induced Changes in Glycolytic Metabolism Regulate Dendritic Cell Activation

    Connie M. Krawczyk;Connie M. Krawczyk;Thomas Holowka;Jie Sun;Julianna Blagih

  • Metabolic reprogramming and cancer progression

    Brandon Faubert;Ashley Solmonson;Ralph J. DeBerardinis

  • Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer.

    Ralph J. DeBerardinis;Tzuling Cheng

  • Role of PFKFB3-Driven Glycolysis in Vessel Sprouting

    Katrien De Bock;Maria Georgiadou;Sandra Schoors;Anna Kuchnio

  • Metabolic pathways promoting cancer cell survival and growth.

    Lindsey K. Boroughs;Ralph J. DeBerardinis

  • Reductive carboxylation supports growth in tumour cells with defective mitochondria

    Andrew R. Mullen;William W. Wheaton;Eunsook S. Jin;Pei Hsuan Chen

  • Glutamine and cancer: cell biology, physiology, and clinical opportunities.

    Christopher T. Hensley;Ajla T. Wasti;Ralph J. DeBerardinis

  • Brick by brick: metabolism and tumor cell growth.

    Ralph J. DeBerardinis;Nabil Sayed;Dara Ditsworth;Craig B. Thompson

  • High Frequency Retrotransposition in Cultured Mammalian Cells

    John V. Moran;Susan E. Holmes;Thierry P. Naas;Ralph J. DeBerardinis

  • Oxidative stress inhibits distant metastasis by human melanoma cells

    Elena Piskounova;Michalis Agathocleous;Malea M. Murphy;Zeping Hu

  • The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche

    Tugba Simsek;Fatih Kocabas;Junke Zheng;Ralph J. DeBerardinis

  • Systemic Treatment with the Antidiabetic Drug Metformin Selectively Impairs p53-Deficient Tumor Cell Growth

    Monica Buzzai;Russell G. Jones;Ravi K. Amaravadi;Julian J. Lum

  • Lactate Metabolism in Human Lung Tumors

    Brandon Faubert;Kevin Y. Li;Ling Cai;Christopher T. Hensley

  • Autophagy in metazoans: cell survival in the land of plenty

    Julian J. Lum;Ralph J. DeBerardinis;Ralph J. DeBerardinis;Craig B. Thompson

Frequent Co-Authors

Craig R. Malloy
Craig R. Malloy The University of Texas Southwestern Medical Center
John D. Minna
John D. Minna The University of Texas Southwestern Medical Center
Robert Bachoo
Robert Bachoo The University of Texas Southwestern Medical Center
Michael A. White
Michael A. White Ideaya Biosciences (United States)
Craig B. Thompson
Craig B. Thompson Memorial Sloan Kettering Cancer Center
Fang Huang
Fang Huang University of Science and Technology of China
Navdeep S. Chandel
Navdeep S. Chandel Northwestern University
Luc Girard
Luc Girard The University of Texas Southwestern Medical Center
Adi F. Gazdar
Adi F. Gazdar The University of Texas Southwestern Medical Center
Sean J. Morrison
Sean J. Morrison The University of Texas Southwestern Medical Center

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