World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
131
Citations
101124
World Ranking
384
National Ranking
253

Overview

Navdeep S. Chandel is affiliated with Northwestern University in the United States. Their research primarily spans biochemistry, genetics, and molecular biology, with a significant focus on medicine. Their scholarly output covers multiple subfields including molecular biology, cancer research, immunology, physiology, and clinical biochemistry.

The main topics that Navdeep S. Chandel investigates include mitochondrial function and pathology, cancer, hypoxia, and metabolism, ATP synthase and ATPases research, metabolism and genetic disorders, epigenetics and DNA methylation, adipose tissue and metabolism, as well as immune cells in cancer.

The scientist has published extensively in several venues, with notable frequent publication outlets being bioRxiv (Cold Spring Harbor Laboratory), Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, Journal of Clinical Investigation, Cold Spring Harbor Perspectives in Biology, and Science Advances.

Among the recent papers associated with Navdeep S. Chandel's research interests are:

  • Mitochondrial TCA cycle metabolites control physiology and disease, 2020, Nature Communications
  • Cancer metabolism: looking forward, 2021, Nature Reviews. Cancer
  • Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology, 2022, Nature Reviews Molecular Cell Biology
  • Cellular adaptation to hypoxia through hypoxia inducible factors and beyond, 2020, Nature Reviews Molecular Cell Biology
  • We need to talk about the Warburg effect, 2020, Nature Metabolism

Navdeep S. Chandel has collaborated frequently with several co-authors, including Ram Prosad Chakrabarty, G. R. Scott Budinger, Karthik Vasan, Samuel E. Weinberg, and Colleen R. Reczek.

Best Publications

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • ROS Function in Redox Signaling and Oxidative Stress

    Michael Schieber;Navdeep S. Chandel

  • Physiological roles of mitochondrial reactive oxygen species.

    Laura A. Sena;Navdeep S. Chandel

  • Fundamentals of cancer metabolism

    Ralph J. DeBerardinis;Navdeep S. Chandel

  • Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing.

    N S Chandel;D S McClintock;C E Feliciano;T M Wood

  • Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

    N. S. Chandel;E. Maltepe;E. Goldwasser;C. E. Mathieu

  • Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

    Frank Weinberg;Robert Hamanaka;William W. Wheaton;Samuel Weinberg

  • Mitochondrial TCA cycle metabolites control physiology and disease.

    Inmaculada Martínez-Reyes;Navdeep S. Chandel

  • Bcl-xL Regulates the Membrane Potential and Volume Homeostasis of Mitochondria

    Matthew G. Vander Heiden;Navdeep S. Chandel;Edward K. Williamson;Paul T. Schumacker

  • Mitochondria Are Required for Antigen-Specific T Cell Activation through Reactive Oxygen Species Signaling

    Laura A. Sena;Sha Li;Amit Jairaman;Murali Prakriya

  • Reductive carboxylation supports growth in tumour cells with defective mitochondria

    Andrew R. Mullen;William W. Wheaton;Eunsook S. Jin;Pei Hsuan Chen

  • Targeting mitochondria metabolism for cancer therapy

    Samuel E Weinberg;Navdeep S Chandel

  • Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

    L. Galluzzi;J. M. Bravo-San Pedro;I. Vitale;S. A. Aaronson

  • AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress

    Sang Min Jeon;Navdeep S. Chandel;Nissim Hay

  • Cancer metabolism: looking forward

    Inmaculada Martínez-Reyes;Navdeep S. Chandel

  • Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes

    Robert B. Hamanaka;Navdeep S. Chandel

  • Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis

    William W Wheaton;Samuel E Weinberg;Robert B Hamanaka;Saul Soberanes

  • ROS-dependent signal transduction.

    Colleen R Reczek;Navdeep S Chandel

  • Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span.

    Alexander V. Misharin;Luisa Morales-Nebreda;Paul A. Reyfman;Carla M. Cuda

  • Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation

    Joslyn K. Brunelle;Eric L. Bell;Nancy M. Quesada;Kristel Vercauteren

Frequent Co-Authors

G. R. Scott Budinger
G. R. Scott Budinger Northwestern University
Paul T. Schumacker
Paul T. Schumacker Northwestern University
Jacob I. Sznajder
Jacob I. Sznajder Northwestern University
Karen M. Ridge
Karen M. Ridge Northwestern University
Harris Perlman
Harris Perlman Northwestern University
Ralph J. DeBerardinis
Ralph J. DeBerardinis The University of Texas Southwestern Medical Center
William E. Balch
William E. Balch Scripps Health
David W. Kamp
David W. Kamp Northwestern University
Richard I. Morimoto
Richard I. Morimoto Northwestern University
Craig B. Thompson
Craig B. Thompson Memorial Sloan Kettering Cancer Center

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