World's Best Scientists 2026 revealed!
G. R. Scott Budinger

G. R. Scott Budinger

D-Index & Metrics

Biology and Biochemistry

D-Index
75
Citations
24381
World Ranking
5243
National Ranking
2495

Medicine

D-Index
75
Citations
24509
World Ranking
19045
National Ranking
9496

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

G. R. Scott Budinger is affiliated with Northwestern University in the United States. Their research spans extensively within the field of Medicine, with a particular focus on subfields such as Pulmonary and Respiratory Medicine, Surgery, Molecular Biology, Immunology, and Infectious Diseases.

The scientist's main areas of study include transplantation methods and outcomes, neonatal respiratory health research, mechanical circulatory support devices, respiratory support and mechanisms, COVID-19 clinical research studies, interstitial lung diseases and idiopathic pulmonary fibrosis, and long-term effects of COVID-19.

Frequent publication venues for their work include bioRxiv (Cold Spring Harbor Laboratory), the Journal of Clinical Investigation, American Journal of Respiratory Cell and Molecular Biology, American Journal of Respiratory and Critical Care Medicine, and JCI Insight.

Budinger has collaborated extensively with several co-authors, notably Alexander V. Misharin, Ankit Bharat, Richard G. Wunderink, Hiam Abdala-Valencia, and Benjamin D. Singer.

Selected recent papers highlight their contributions to understanding respiratory disease and COVID-19-related outcomes:

  • Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia, 2021, Nature
  • Mitochondrial ubiquinol oxidation is necessary for tumour growth, 2020, Nature
  • Lung transplantation for patients with severe COVID-19, 2020, Science Translational Medicine
  • Local and systemic responses to SARS-CoV-2 infection in children and adults, 2021, Nature
  • Early outcomes after lung transplantation for severe COVID-19: a series of the first consecutive cases from four countries, 2021, The Lancet Respiratory Medicine

The researcher holds membership in the Association of American Physicians.

Best Publications

  • Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

    Frank Weinberg;Robert Hamanaka;William W. Wheaton;Samuel Weinberg

  • Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis.

    Paul Andrew Reyfman;James McCauley Walter;Nikita Joshi;Kishore R. Anekalla

  • Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span.

    Alexander V. Misharin;Luisa Morales-Nebreda;Paul A. Reyfman;Carla M. Cuda

  • Flow Cytometric Analysis of Macrophages and Dendritic Cell Subsets in the Mouse Lung

    Alexander V. Misharin;Luisa Morales-Nebreda;Gökhan M. Mutlu;G. R. Scott Budinger

  • Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia.

    Rogan A Grant;Luisa Morales-Nebreda;Nikolay S Markov;Suchitra Swaminathan

  • The role of macrophages in the resolution of inflammation

    Satoshi Watanabe;Satoshi Watanabe;Michael Alexander;Alexander V. Misharin;G.R. Scott Budinger

  • The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production

    Eric L. Bell;Tatyana A. Klimova;James Eisenbart;Carlos T. Moraes

  • Minimizing Oxidation and Stable Nanoscale Dispersion Improves the Biocompatibility of Graphene in the Lung

    Matthew C. Duch;G. R. Scott Budinger;Yu Teng Liang;Saul Soberanes

  • Influenza virus-induced lung injury: pathogenesis and implications for treatment

    Susanne Herold;Christin Becker;Karen M. Ridge;G.R. Scott Budinger

  • Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio.

    Brooke M. Emerling;Frank Weinberg;Colleen Snyder;Zach Burgess

  • Mitochondrial Reactive Oxygen Species Regulate Transforming Growth Factor-β Signaling

    Manu Jain;Stephanie Rivera;Elena A. Monclus;Lauren Synenki

  • Ambient particulate matter accelerates coagulation via an IL-6-dependent pathway.

    Gökhan M. Mutlu;David Green;Amy Bellmeyer;Christina M. Baker

  • Nonclassical Ly6C− Monocytes Drive the Development of Inflammatory Arthritis in Mice

    Alexander V. Misharin;Carla M. Cuda;Rana Saber;Jason D. Turner

  • The cellular basis for diverse responses to oxygen.

    Navdeep S. Chandel;G.R. Scott Budinger

  • Hypoxic but not anoxic stabilization of HIF-1α requires mitochondrial reactive oxygen species

    Clara Schroedl;David S. McClintock;G. R. Scott Budinger;Navdeep S. Chandel

  • Toll-like receptor 4 signaling augments transforming growth factor-β responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma.

    Swati Bhattacharyya;Kathleen Kelley;Denisa S. Melichian;Zenshiro Tamaki

  • Lung transplantation for patients with severe COVID-19.

    Ankit Bharat;Melissa Querrey;Nikolay S. Markov;Samuel Kim

  • Bcl-2 family members and functional electron transport chain regulate oxygen deprivation-induced cell death.

    David S. McClintock;Matthew T. Santore;Vivian Y. Lee;Joslyn Brunelle

  • Tenascin-C drives persistence of organ fibrosis.

    Swati Bhattacharyya;Wenxia Wang;Luisa Morales-Nebreda;Gang Feng

  • Mitochondrial ubiquinol oxidation is necessary for tumour growth.

    Inmaculada Martínez-Reyes;Luzivette Robles Cardona;Hyewon Kong;Karthik Vasan

Frequent Co-Authors

Navdeep S. Chandel
Navdeep S. Chandel Northwestern University
Jacob I. Sznajder
Jacob I. Sznajder Northwestern University
Harris Perlman
Harris Perlman Northwestern University
Karen M. Ridge
Karen M. Ridge Northwestern University
Cara J. Gottardi
Cara J. Gottardi Northwestern University
David W. Kamp
David W. Kamp Northwestern University
William E. Balch
William E. Balch Scripps Health
Richard I. Morimoto
Richard I. Morimoto Northwestern University
Paul T. Schumacker
Paul T. Schumacker Northwestern University
Ali Shilatifard
Ali Shilatifard Northwestern University

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