D-Index & Metrics Best Publications
Matthew G. Vander Heiden

Matthew G. Vander Heiden

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 99 Citations 65,403 317 World Ranking 1029 National Ranking 634

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Cancer

Biochemistry, Cell biology, Glycolysis, Pyruvate kinase and PKM2 are his primary areas of study. His work carried out in the field of Cell biology brings together such families of science as Cell culture, Cell growth and Metabolic pathway. His Cell growth study incorporates themes from Carcinogenesis, Carbohydrate metabolism and Biosynthesis.

His Glycolysis research incorporates themes from Cancer cell, Signal transduction and Serine. His studies deal with areas such as Enzyme activator, Pyruvate dehydrogenase kinase, Pyruvate dehydrogenase phosphatase, Intracellular and Gene isoform as well as Pyruvate kinase. His work focuses on many connections between PKM2 and other disciplines, such as Phosphorylation, that overlap with his field of interest in Tyrosine kinase.

His most cited work include:

  • Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation (8625 citations)
  • Cancer-associated IDH1 mutations produce 2-hydroxyglutarate (2608 citations)
  • Cancer-associated IDH1 mutations produce 2-hydroxyglutarate (2608 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Biochemistry, Cell biology, Cancer research, Cancer cell and Cancer. All of his Biochemistry and Metabolism, Glutamine, Pyruvate kinase, PKM2 and Glycolysis investigations are sub-components of the entire Biochemistry study. His research investigates the connection between Cell biology and topics such as Cell growth that intersect with issues in Amino acid and Intracellular.

Matthew G. Vander Heiden has researched Cancer research in several fields, including Carcinogenesis, Leukemia, Metastasis and In vivo. His studies in Cancer cell integrate themes in fields like Pancreatic cancer, Serine, Biosynthesis, Enzyme and Extracellular. His Cancer study integrates concerns from other disciplines, such as Pharmacology and Bioinformatics.

He most often published in these fields:

  • Biochemistry (53.20%)
  • Cell biology (51.00%)
  • Cancer research (43.80%)

What were the highlights of his more recent work (between 2019-2021)?

  • Cancer research (43.80%)
  • Cancer cell (47.00%)
  • Cell biology (51.00%)

In recent papers he was focusing on the following fields of study:

His main research concerns Cancer research, Cancer cell, Cell biology, Metabolism and In vivo. The various areas that Matthew G. Vander Heiden examines in his Cancer research study include Cell culture, Cell and Metastasis, Brain metastasis. To a larger extent, Matthew G. Vander Heiden studies Cancer with the aim of understanding Cancer cell.

Matthew G. Vander Heiden combines subjects such as Lipogenesis, Heme binding, ATP synthase and Cell growth with his study of Cell biology. His Metabolism study is associated with Biochemistry. His In vivo research includes themes of Carcinogenesis, Protein kinase B, Neutralizing antibody and p38 mitogen-activated protein kinases.

Between 2019 and 2021, his most popular works were:

  • Emerging Roles for Branched-Chain Amino Acid Metabolism in Cancer. (34 citations)
  • Emerging Roles for Branched-Chain Amino Acid Metabolism in Cancer. (34 citations)
  • Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition. (25 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Cancer

Matthew G. Vander Heiden spends much of his time researching Cancer research, Cancer cell, In vivo, Cell and Cell type. His work in the fields of Cancer research, such as Stromal cell, intersects with other areas such as Netrin. His Cancer cell study is concerned with the larger field of Cancer.

His biological study spans a wide range of topics, including Branched-chain amino acid, Epigenetics and Metabolic pathway. The study incorporates disciplines such as Immune system, Metabolism and Cell biology in addition to Cell type. His Cell biology study which covers Cancer metabolism that intersects with Tumor microenvironment.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

Matthew G. Vander Heiden;Lewis C. Cantley;Craig B. Thompson.
Science (2009)

13650 Citations

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

Lenny Dang;David W. White;Stefan Gross;Bryson D. Bennett.
Nature (2009)

3923 Citations

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

Heather R. Christofk;Matthew G. Vander Heiden;Marian H. Harris;Arvind Ramanathan.
Nature (2008)

2877 Citations

Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation

Sophia Y. Lunt;Matthew G. Vander Heiden.
Annual Review of Cell and Developmental Biology (2011)

1990 Citations

Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1

Katrin Düvel;Jessica L. Yecies;Suchithra Menon;Pichai Raman.
Molecular Cell (2010)

1867 Citations

Bcl-xL Regulates the Membrane Potential and Volume Homeostasis of Mitochondria

Matthew G. Vander Heiden;Navdeep S. Chandel;Edward K. Williamson;Paul T. Schumacker.
Cell (1997)

1638 Citations

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

Christian M. Metallo;Paulo A. Gameiro;Eric L. Bell;Katherine R. Mattaini.
Nature (2012)

1617 Citations

Targeting cancer metabolism: a therapeutic window opens

Matthew G. Vander Heiden;Matthew G. Vander Heiden.
Nature Reviews Drug Discovery (2011)

1514 Citations

Understanding the Intersections between Metabolism and Cancer Biology

Matthew G. Vander Heiden;Matthew G. Vander Heiden;Ralph J. DeBerardinis.
Cell (2017)

1307 Citations

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

Cosimo Commisso;Shawn M. Davidson;Rengin G. Soydaner-Azeloglu;Seth J. Parker.
Nature (2013)

1293 Citations

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