D-Index & Metrics Best Publications
Research.com 2022 Best Scientist Award Badge
Molecular Biology
USA
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Best Scientists D-index 168 Citations 136,533 454 World Ranking 643 National Ranking 424
Molecular Biology D-index 163 Citations 130,187 445 World Ranking 27 National Ranking 20

Research.com Recognitions

Awards & Achievements

2023 - Research.com Molecular Biology in United States Leader Award

2022 - Research.com Best Scientist Award

2010 - Fellow of the American Association for the Advancement of Science (AAAS)

1998 - Fellow of the MacArthur Foundation

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Cancer

His primary areas of study are Cell biology, Biochemistry, Hippo signaling pathway, PI3K/AKT/mTOR pathway and Signal transduction. His Cell biology research includes elements of Autophagy, Transcription factor and Cell growth. He combines subjects such as Tissue homeostasis, WWTR1, Nuclear protein and Cell polarity with his study of Hippo signaling pathway.

In his research, TSC1 is intimately related to Cancer research, which falls under the overarching field of PI3K/AKT/mTOR pathway. His research integrates issues of Gene expression and Cellular differentiation in his study of Signal transduction. He has researched Phosphorylation in several fields, including Transcription and Kinase.

His most cited work include:

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (4170 citations)
  • AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1 (3674 citations)
  • Guidelines for the use and interpretation of assays for monitoring autophagy (3242 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Cell biology, Biochemistry, Signal transduction, Hippo signaling pathway and Phosphorylation. His Cell biology study combines topics from a wide range of disciplines, such as Transcription factor and Cell growth. His study focuses on the intersection of Biochemistry and fields such as Molecular biology with connections in the field of c-Raf and Isocitrate dehydrogenase.

His Signal transduction study frequently draws parallels with other fields, such as HEK 293 cells. Kun-Liang Guan has included themes like Cancer research, Tissue homeostasis and WWTR1 in his Hippo signaling pathway study. His Cancer research research incorporates elements of Carcinogenesis and Suppressor.

He most often published in these fields:

  • Cell biology (67.98%)
  • Biochemistry (34.38%)
  • Signal transduction (26.52%)

What were the highlights of his more recent work (between 2015-2021)?

  • Cell biology (67.98%)
  • Hippo signaling pathway (23.97%)
  • Cancer research (22.99%)

In recent papers he was focusing on the following fields of study:

Kun-Liang Guan mainly focuses on Cell biology, Hippo signaling pathway, Cancer research, Cell growth and Phosphorylation. His Cell biology study integrates concerns from other disciplines, such as Cell, Tissue homeostasis and Transcription factor. His studies in Hippo signaling pathway integrate themes in fields like Carcinogenesis and YAP1.

His Cancer research research includes themes of Cancer, Suppressor, Signal transducing adaptor protein, Cancer immunotherapy and RHOA. His research in Cell growth intersects with topics in Receptor, G protein-coupled receptor, Actin cytoskeleton, Ubiquitin ligase and Cell polarity. His mTORC1 study is concerned with the larger field of Biochemistry.

Between 2015 and 2021, his most popular works were:

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (4170 citations)
  • Mechanisms of Hippo pathway regulation (680 citations)
  • mTOR as a central hub of nutrient signalling and cell growth. (285 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Cancer

The scientist’s investigation covers issues in Cell biology, Hippo signaling pathway, Cell growth, Transcription factor and Tissue homeostasis. His work deals with themes such as Regulator, Biochemistry and DNA damage, which intersect with Cell biology. The study incorporates disciplines such as Cell and Cancer research in addition to Hippo signaling pathway.

The concepts of his Cell growth study are interwoven with issues in Oxidative stress, Cancer, Actin cytoskeleton, Stem cell and Programmed cell death. His studies examine the connections between Transcription factor and genetics, as well as such issues in HEK 293 cells, with regards to Extracellular matrix, RHOA, Interactome, Regulation of gene expression and WWTR1. His Phosphorylation study combines topics in areas such as Cytoplasm and BECN1.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham.
Autophagy (2012)

8302 Citations

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin.
Autophagy (2016)

7788 Citations

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Joungmok Kim;Mondira Kundu;Benoit Viollet;Kun-Liang Guan.
Nature Cell Biology (2011)

5707 Citations

TSC2 mediates cellular energy response to control cell growth and survival.

Ken Inoki;Tianqing Zhu;Kun Liang Guan.
Cell (2003)

4262 Citations

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

Ken Inoki;Yong Li;Tianquan Zhu;Jun Wu.
Nature Cell Biology (2002)

3510 Citations

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

Bin Zhao;Xiaomu Wei;Weiquan Li;Ryan S. Udan;Ryan S. Udan.
Genes & Development (2007)

2664 Citations

Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases

Wei Xu;Hui Yang;Ying Liu;Ying Yang.
Cancer Cell (2011)

2568 Citations

Eukaryotic proteins expressed in Escherichia coli: an improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase.

KunLiang Guan;Jack E. Dixon.
Analytical Biochemistry (1991)

2317 Citations

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

Ken Inoki;Yong Li;Tian Xu;Kun Liang Guan.
Genes & Development (2003)

2084 Citations

TEAD mediates YAP-dependent gene induction and growth control

Bin Zhao;Xin Ye;Jindan Yu;Li Li;Li Li.
Genes & Development (2008)

2073 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing Kun-Liang Guan

David M. Sabatini

David M. Sabatini

MIT

Publications: 117

Benoit Viollet

Benoit Viollet

Institut Cochin

Publications: 116

Guido Kroemer

Guido Kroemer

Sorbonne University

Publications: 82

Daniel J. Klionsky

Daniel J. Klionsky

University of Michigan–Ann Arbor

Publications: 80

Michael N. Hall

Michael N. Hall

University of Basel

Publications: 77

Patrice Codogno

Patrice Codogno

Université Paris Cité

Publications: 75

Christopher G. Proud

Christopher G. Proud

University of Adelaide

Publications: 73

Lewis C. Cantley

Lewis C. Cantley

Cornell University

Publications: 73

Matthew G. Vander Heiden

Matthew G. Vander Heiden

MIT

Publications: 71

Marius Sudol

Marius Sudol

Icahn School of Medicine at Mount Sinai

Publications: 70

Kieran F. Harvey

Kieran F. Harvey

Peter MacCallum Cancer Centre

Publications: 67

Jack E. Dixon

Jack E. Dixon

University of California, San Diego

Publications: 66

Scot R. Kimball

Scot R. Kimball

Pennsylvania State University

Publications: 63

David J. Kwiatkowski

David J. Kwiatkowski

Brigham and Women's Hospital

Publications: 61

David C. Rubinsztein

David C. Rubinsztein

University of Cambridge

Publications: 60

Craig B. Thompson

Craig B. Thompson

Memorial Sloan Kettering Cancer Center

Publications: 60

Trending Scientists

Jan Bosch

Jan Bosch

Chalmers University of Technology

Jean-Pierre Seifert

Jean-Pierre Seifert

Technical University of Berlin

Belgacem Haba

Belgacem Haba

Stanford University

Noah Montena

Noah Montena

Syracuse University

Xiaodong Wang

Xiaodong Wang

Beijing University of Chemical Technology

Gerhardus Venema

Gerhardus Venema

University of Groningen

Elena Maestrini

Elena Maestrini

University of Bologna

John C. Mitani

John C. Mitani

University of Michigan–Ann Arbor

Thierry Lorca

Thierry Lorca

University of Montpellier

Bent Borg Jensen

Bent Borg Jensen

Aarhus University

Jon A. Arnot

Jon A. Arnot

University of Toronto

Bruce M. Hall

Bruce M. Hall

University of New South Wales

Robert J. McMahon

Robert J. McMahon

Simon Fraser University

Arpana Agrawal

Arpana Agrawal

Washington University in St. Louis

Ivana Marková

Ivana Marková

University of Stirling

Ahmad Reza Hosseinpoor

Ahmad Reza Hosseinpoor

World Health Organization

Something went wrong. Please try again later.