2026 Kun-Liang Guan: Molecular Biology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Best Scientists	176	686	628	427	382	501	154171
Molecular Biology	178	36	31	24	22	467	138664

Research.com Recognitions

2026 - Research.com Molecular Biology in United States Leader Award
2025 - Research.com Best Scientists Award
2025 - Research.com Molecular Biology in United States Leader Award
2024 - Research.com Genetics and Molecular Biology in United States Leader Award
2023 - Research.com Molecular Biology in United States Leader Award
2010 - Fellow of the American Association for the Advancement of Science (AAAS)
1998 - Fellow of the MacArthur Foundation

Overview

Kun-Liang Guan is affiliated with Westlake University in China. Their research primarily focuses on the field of Biochemistry, Genetics and Molecular Biology, with a particular emphasis on Molecular Biology, Cell Biology, Cancer Research, Immunology, and Physiology.

The scientist's main topics of work include:

Hippo pathway signaling and YAP/TAZ
Cancer, Hypoxia, and Metabolism
Wnt/β-catenin signaling in development and cancer
Cancer, Lipids, and Metabolism
Ubiquitin and proteasome pathways
Epigenetics and DNA Methylation
Immune cells in cancer

Their frequent collaborators include Dan Ye, Yue Xiong (listed with three separate entries indicating multiple collaborations), and Qun-Ying Lei.

Kun-Liang Guan has published extensively in a variety of venues. The most frequent publication venues include:

UNC Libraries
Trends in Biochemical Sciences
Nature Cell Biology
Nature Communications
Science Advances

Recent publications by Kun-Liang Guan and coauthors encompass significant topics in signaling pathways, cancer biology, and liver disease, including:

"Targeting the Hippo pathway in cancer, fibrosis, wound healing and regenerative medicine," 2020, Nature Reviews Drug Discovery
"The Hippo signalling pathway and its implications in human health and diseases," 2022, Signal Transduction and Targeted Therapy
"Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity," 2020, Cell Stem Cell
"Targeting ferroptosis alleviates methionine-choline deficient (MCD)-diet induced NASH by suppressing liver lipotoxicity," 2020, Liver International
"Hippo Signaling in Embryogenesis and Development," 2020, Trends in Biochemical Sciences

In recognition of contributions to science, Kun-Liang Guan was named a Fellow of the MacArthur Foundation in 1998 and a Fellow of the American Association for the Advancement of Science (AAAS) in 2010.

Best Publications

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

8665
Citations
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

8488
Citations
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Joungmok Kim;Mondira Kundu;Benoit Viollet;Kun-Liang Guan

6992
Citations
TSC2 mediates cellular energy response to control cell growth and survival.

Ken Inoki;Tianqing Zhu;Kun Liang Guan

4608
Citations
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

Ken Inoki;Yong Li;Tianquan Zhu;Jun Wu

3750
Citations
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

Bin Zhao;Xiaomu Wei;Weiquan Li;Ryan S. Udan;Ryan S. Udan

3182
Citations
Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases

Wei Xu;Hui Yang;Ying Liu;Ying Yang

2967
Citations
TEAD mediates YAP-dependent gene induction and growth control

Bin Zhao;Xin Ye;Jindan Yu;Li Li;Li Li

2505
Citations
Eukaryotic proteins expressed in Escherichia coli: an improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase.

KunLiang Guan;Jack E. Dixon

2324
Citations
Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

Ken Inoki;Yong Li;Tian Xu;Kun Liang Guan

2257
Citations
Regulation of cellular metabolism by protein lysine acetylation.

Shimin Zhao;Wei Xu;Wenqing Jiang;Wei Yu

2179
Citations
Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer.

Fa Xing Yu;Bin Zhao;Kun Liang Guan

2062
Citations
mTOR: a pharmacologic target for autophagy regulation

Young Chul Kim;Kun-Liang Guan

1821
Citations
ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase

Ryan C. Russell;Ye Tian;Haixin Yuan;Hyun Woo Park

1672
Citations
Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling

Fa Xing Yu;Bin Zhao;Nattapon Panupinthu;Jenna L. Jewell

1639
Citations
TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth

Ken Inoki;Hongjiao Ouyang;Tianqing Zhu;Charlotta Lindvall

1558
Citations
Mechanisms of Hippo pathway regulation

Zhipeng Meng;Toshiro Moroishi;Kun-Liang Guan

1529
Citations
Regulation of TORC1 by Rag GTPases in nutrient response.

Eunjung Kim;Pankuri Goraksha-Hicks;Li Li;Thomas P. Neufeld

1521
Citations
The Hippo–YAP pathway in organ size control and tumorigenesis: an updated version

Bin Zhao;Li Li;Qunying Lei;Kun-Liang Guan

1472
Citations
TSC2 is phosphorylated and inhibited by Akt and suppresses

Ken Inoki;Yong Li;Tianquan Zhu;Jun Wu

1
Citations

Frequent Co-Authors

Yue Xiong University of North Carolina at Chapel Hill

Qun-Ying Lei Fudan University

Ken Inoki University of Michigan–Ann Arbor

Cun-Yu Wang University of California, Los Angeles

Jack E. Dixon University of California, San Diego

Yan Lin Shanghai Jiao Tong University

Yanhui Xu Shanghai Medical College of Fudan University

Min Han University of Colorado Boulder

Ming You Medical College of Wisconsin

Bing Ren New York Genome Center

External Links

Wikipedia of Kun-Liang Guan Personal website of Kun-Liang Guan

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