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Chemistry
Italy
2025

D-Index & Metrics

Chemistry

D-Index
80
Citations
24429
World Ranking
3399
National Ranking
60

Research.com Recognitions

  • 2025 - Research.com Chemistry in Italy Leader Award
  • 2022 - Research.com Chemistry in Italy Leader Award

Overview

Giovanni Appendino is affiliated with the University of Eastern Piedmont Amadeo Avogadro in Italy. Their research primarily spans the fields of biochemistry, genetics, and molecular biology, with significant contributions also in medicine. Within these disciplines, they focus on subfields such as molecular biology, pharmacology, plant science, nutrition, dietetics, and organic chemistry.

Their work addresses various scientific topics, notably cannabis and cannabinoid research, natural product bioactivities and synthesis, GABA and rice research, biochemical analysis and sensing techniques, microbial natural products and biosynthesis, diet, metabolism, and disease, as well as plant biochemistry and biosynthesis.

Recent publications by Giovanni Appendino include:

  • Δ9-cis-Tetrahydrocannabinol: Natural Occurrence, Chirality, and Pharmacology, 2021, Journal of Natural Products
  • Pitfalls in the structural elucidation of small molecules. A critical analysis of a decade of structural misassignments of marine natural products, 2022, Natural Product Reports
  • The Oxidation of Phytocannabinoids to Cannabinoquinoids, 2020, Journal of Natural Products
  • The early history of cannabinoid research, 2020, RENDICONTI LINCEI
  • Plant triterpenoids with bond-missing skeletons: biogenesis, distribution and bioactivity, 2020, Natural Product Reports

Giovanni Appendino frequently collaborates with several researchers in their field. Notable co-authors include Eduardo Muñóz, Orazio Taglialatela-Scafati, Diego Caprioglio, Federica Pollastro, and Alberto Minassi.

The primary venues for their scientific contributions are:

  • Journal of Natural Products
  • Natural Product Reports
  • Fitoterapia
  • European Journal of Organic Chemistry
  • Biomolecules

Best Publications

  • The molecular receptive ranges of human TAS2R bitter taste receptors.

    Wolfgang Meyerhof;Claudia Batram;Christina Kuhn;Anne Brockhoff

  • Phytocannabinoids: a unified critical inventory.

    Lumír Ondřej Hanuš;Stefan Martin Meyer;Eduardo Muñoz;Orazio Taglialatela-Scafati

  • Antibacterial cannabinoids from Cannabis sativa: a structure-activity study.

    Giovanni Appendino;Simon Gibbons;Anna Giana;Alberto Pagani

  • The vinylogous aldol reaction: a valuable, yet understated carbon-carbon bond-forming maneuver.

    Giovanni Casiraghi;Franca Zanardi;Giovanni Appendino;Gloria Rassu

  • Best practice in research - Overcoming common challenges in phytopharmacological research

    Michael Heinrich;Giovanni Appendino;Thomas Efferth;Robert Fürst

  • The transient receptor potential channel TRPA1: from gene to pathophysiology

    Bernd Nilius;Giovanni Appendino;Grzegorz Owsianik

  • Comparative absorption of a standardized curcuminoid mixture and its lecithin formulation

    John Cuomo;Giovanni Appendino;Adam S. Dern;Erik Schneider

  • N-oleoyldopamine, a novel endogenous capsaicin-like lipid that produces hyperalgesia.

    Constance J. Chu;Susan M. Huang;Luciano De Petrocellis;Tiziana Bisogno

  • Pharmacology of vanilloid transient receptor potential cation channels.

    Joris Vriens;Giovanni Appendino;Bernd Nilius

  • Efficacy and safety of Meriva®, a curcumin-phosphatidylcholine complex, during extended administration in osteoarthritis patients.

    Gianni Belcaro;Maria Rosaria Cesarone;Mark Dugall;Luciano Pellegrini

  • Broad tuning of the human bitter taste receptor hTAS2R46 to various sesquiterpene lactones, clerodane and labdane diterpenoids, strychnine, and denatonium.

    Anne Brockhoff;Maik Behrens;Alberto Massarotti;Giovanni Appendino

  • Antioxidant activity of capsinoids.

    Antonella Rosa;Monica Deiana;Viviana Casu;Stefania Paccagnini

  • The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system

    Romina Nassini;Serena Materazzi;Joris Joris vriens;Jean Prenen

  • Vanilloid receptor TRPV1 antagonists as the next generation of painkillers. Are we putting the cart before the horse

    Arpad Szallasi;Giovanni Appendino

  • Arzanol, an anti-inflammatory and anti-HIV-1 phloroglucinol alpha-Pyrone from Helichrysum italicum ssp. microphyllum.

    Giovanni Appendino;Michela Ottino;Nieves Marquez;Federica Bianchi

  • Cannabinoids: occurrence and medicinal chemistry.

    G. Appendino;G. Chianese;O. Taglialatela-Scafati

  • An NMR Spectroscopic Method to Identify and Classify Thiol-Trapping Agents: Revival of Michael Acceptors for Drug Discovery?

    Cristina Avonto;Orazio Taglialatela-Scafati;Federica Pollastro;Alberto Minassi

  • Immunosuppressive activity of capsaicinoids : capsiate derived from sweet peppers inhibits NF-κB activation and is a potent antiinflammatory compound in vivo

    Rocío Sancho;Concepción Lucena;Antonio Macho;Marco A. Calzado

  • Spices: the savory and beneficial science of pungency.

    Bernd Nilius;Giovanni Appendino

  • Development of the first potent and specific inhibitors of endocannabinoid biosynthesis.

    Tiziana Bisogno;Maria Grazia Cascio;Bijali Saha;Anu Mahadevan

  • Hyperforin inhibits cancer invasion and metastasis

    Massimo Donà;Isabella Dell’Aica;Elga Pezzato;Luigi Sartor

Frequent Co-Authors

Eduardo Muñoz
Eduardo Muñoz University of Córdoba
Giancarlo Cravotto
Giancarlo Cravotto University of Turin
Olov Sterner
Olov Sterner Lund University
Vincenzo Di Marzo
Vincenzo Di Marzo National Research Council (CNR)
Jasmin Jakupovic
Jasmin Jakupovic AnalytiCon Discovery GmbH
Giovanni Palmisano
Giovanni Palmisano Khalifa University
Ezio Bombardelli
Ezio Bombardelli Magna Graecia University
Gian Cesare Tron
Gian Cesare Tron University of Eastern Piedmont Amadeo Avogadro
Pierangelo Geppetti
Pierangelo Geppetti University of Florence
Giovanni Casiraghi
Giovanni Casiraghi University of Parma

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