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D-Index & Metrics

Biology and Biochemistry

D-Index
87
Citations
47872
World Ranking
2768
National Ranking
172

Overview

Makoto Tominaga is affiliated with the National Institutes of Natural Sciences in Japan. Their research primarily spans the fields of neuroscience and medicine, with a focus on sensory systems, cellular and molecular neuroscience, physiology, nutrition and dietetics, and molecular biology.

The scientist's work centers on topics such as ion channels and receptors, neurobiology and insect physiology research, biochemical analysis and sensing techniques, respiratory and cough-related research, ion channel regulation and function, pain mechanisms and treatments, and circadian rhythm and melatonin.

Tominaga has contributed to numerous publications in a variety of scientific journals. Frequent publication venues include The Journal of Physiological Sciences, bioRxiv (Cold Spring Harbor Laboratory), Scientific Reports, Communications Biology, and Nature Communications.

Recent papers authored or co-authored by Makoto Tominaga include:

  • TRP channels in thermosensation (2022) published in Current Opinion in Neurobiology
  • RNA Sensing by Gut Piezo1 Is Essential for Systemic Serotonin Synthesis (2020) published in Cell
  • The structure of lipid nanodisc-reconstituted TRPV3 reveals the gating mechanism (2020) published in Nature Structural & Molecular Biology
  • TMC4 is a novel chloride channel involved in high-concentration salt taste sensation (2021) published in The Journal of Physiological Sciences
  • A unique mode of keratinocyte death requires intracellular acidification (2021) published in Proceedings of the National Academy of Sciences

Co-authorship collaborations are a significant aspect of Tominaga's research. Frequent co-authors include:

  • Makiko Kashio (13 joint publications)
  • Sandra Derouiche (11 joint publications)
  • Jing Lei (10 joint publications)
  • Takaaki Sokabe (10 joint publications)
  • Yasunori Takayama (9 joint publications)

Best Publications

  • The capsaicin receptor: a heat-activated ion channel in the pain pathway

    Michael J. Caterina;Mark A. Schumacher;Makoto Tominaga;Tobias A. Rosen

  • The Cloned Capsaicin Receptor Integrates Multiple Pain-Producing Stimuli

    Makoto Tominaga;Michael J Caterina;Annika B Malmberg;Tobias A Rosen

  • A capsaicin-receptor homologue with a high threshold for noxious heat.

    Michael J. Caterina;Tobias A. Rosen;Makoto Tominaga;Anthony J. Brake

  • Heat-Evoked Activation of the Ion Channel, TRPV4

    Ali Deniz Güler;Hyosang Lee;Tohko Iida;Isao Shimizu

  • Hypothalamic orexin neurons regulate arousal according to energy balance in mice.

    Akihiro Yamanaka;Carsten T. Beuckmann;Jon T. Willie;Junko Hara

  • TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury

    Koichi Obata;Hirokazu Katsura;Toshiyuki Mizushima;Hiroki Yamanaka

  • Acid potentiation of the capsaicin receptor determined by a key extracellular site

    Sven-Eric Jordt;Makoto Tominaga;David Julius

  • Sensitization of TRPV1 by EP1 and IP Reveals Peripheral Nociceptive Mechanism of Prostaglandins

    Tomoko Moriyama;Tomoko Moriyama;Tomohiro Higashi;Tomohiro Higashi;Kazuya Togashi;Kazuya Togashi;Tohko Iida

  • Potentiation of capsaicin receptor activity by metabotropic ATP receptors as a possible mechanism for ATP-evoked pain and hyperalgesia

    Makoto Tominaga;Makoto Wada;Masayuki Masu

  • Thermosensation and pain.

    Makoto Tominaga;Michael J. Caterina

  • Direct phosphorylation of capsaicin receptor VR1 by protein kinase Cepsilon and identification of two target serine residues

    Mitsuko Numazaki;Tomoko Tominaga;Hidenori Toyooka;Makoto Tominaga

  • Nitric oxide activates TRP channels by cysteine S-nitrosylation

    Takashi Yoshida;Ryuji Inoue;Takashi Morii;Nobuaki Takahashi

  • Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain

    Yi Dai;Shenglan Wang;Makoto Tominaga;Satoshi Yamamoto

  • TRPM2 activation by cyclic ADP‐ribose at body temperature is involved in insulin secretion

    Kazuya Togashi;Kazuya Togashi;Yuji Hara;Tomoko Tominaga;Tomoko Tominaga;Tomohiro Higashi;Tomohiro Higashi

  • Structure and function of TRPV1

    Makoto Tominaga;Tomoko Tominaga

  • Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor

    Yoshiro Ishimaru;Hitoshi Inada;Momoka Kubota;Hanyi Zhuang

  • α-Klotho as a Regulator of Calcium Homeostasis

    Akihiro Imura;Yoshihito Tsuji;Miyahiko Murata;Ryota Maeda

  • Structural determinant of TRPV1 desensitization interacts with calmodulin.

    Mitsuko Numazaki;Tomoko Tominaga;Kumiko Takeuchi;Namie Murayama

  • Bradykinin Lowers the Threshold Temperature for Heat Activation of Vanilloid Receptor 1

    Takeshi Sugiura;Makoto Tominaga;Hirotada Katsuya;Kazue Mizumura

  • Effects of Body Temperature on Neural Activity in the Hippocampus : Regulation of Resting Membrane Potentials by Transient Receptor Potential Vanilloid 4

    Koji Shibasaki;Makoto Suzuki;Atsuko Mizuno;Makoto Tominaga

Frequent Co-Authors

Akihiro Yamanaka
Akihiro Yamanaka Chinese Academy of Sciences
Yasuo Mori
Yasuo Mori Kyoto University
Kazue Mizumura
Kazue Mizumura Nihon University
Yasunobu Okada
Yasunobu Okada Kyoto Prefectural University of Medicine
Tsuyoshi Goto
Tsuyoshi Goto Kyoto University
Toshihiko Yada
Toshihiko Yada Kobe University
Yi Dai
Yi Dai Hyogo University of Health Sciences
Koichi Noguchi
Koichi Noguchi Hyogo College of Medicine
Tohru Fushiki
Tohru Fushiki Kyoto University
David Julius
David Julius University of California, San Francisco

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