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Tsuyoshi Goto

Tsuyoshi Goto

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
8627
World Ranking
17248
National Ranking
1241

Overview

Tsuyoshi Goto is affiliated with Kyoto University in Japan and has a substantial research output primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their expertise spans several subfields, including Physiology, Molecular Biology, Surgery, Epidemiology, and Cardiology and Cardiovascular Medicine.

Their research topics cover a diverse range, with notable focus on Adipose Tissue and Metabolism, Adipokines, Inflammation, and Metabolic Diseases, Regulation of Appetite and Obesity, Coronary Interventions and Diagnostics, Metabolism, Diabetes, and Cancer, Cardiac Imaging and Diagnostics, and Sirtuins and Resveratrol in Medicine.

Frequently publishing in well-established journals, Tsuyoshi Goto has contributed to Bioscience Biotechnology and Biochemistry, Journal of Biological Chemistry, Circulation Journal, PLoS ONE, and iScience. This pattern reflects their biomedical research interests and collaborations within the discipline.

The scientist has been involved in co-authorship with several prominent researchers, including Teruo Kawada, Kazuo Inoue, Satoko Kawarasaki, Haruya Takahashi, and Wataru Nomura, indicating active collaborative research efforts across multiple projects and papers.

Some of their recent papers illustrate the scope and focus of their research:

  • Single-cell analysis of human skin identifies CD14+ type 3 dendritic cells co-producing IL1B and IL23A in psoriasis, 2021, The Journal of Experimental Medicine
  • Biallelic variants in LIG3 cause a novel mitochondrial neurogastrointestinal encephalomyopathy, 2021, Brain
  • Glycerol kinase stimulates uncoupling protein 1 expression by regulating fatty acid metabolism in beige adipocytes, 2020, Journal of Biological Chemistry
  • Anti-Inflammatory and Antioxidative Properties of Isoflavones Provide Renal Protective Effects Distinct from Those of Dietary Soy Proteins against Diabetic Nephropathy, 2020, Molecular Nutrition & Food Research
  • Prevalence of the Academic Research Consortium for High Bleeding Risk Criteria and Prognostic Value of a Simplified Definition, 2020, Circulation Journal

Best Publications

  • BCAA catabolism in brown fat controls energy homeostasis through SLC25A44.

    Takeshi Yoneshiro;Qiang Wang;Kazuki Tajima;Mami Matsushita

  • Dual action of isoprenols from herbal medicines on both PPARγ and PPARα in 3T3-L1 adipocytes and HepG2 hepatocytes

    Nobuyuki Takahashi;Teruo Kawada;Tsuyoshi Goto;Takayuki Yamamoto

  • Various Terpenoids Derived from Herbal and Dietary Plants Function as PPAR Modulators and Regulate Carbohydrate and Lipid Metabolism

    Tsuyoshi Goto;Nobuyuki Takahashi;Shizuka Hirai;Shizuka Hirai;Teruo Kawada

  • Activation of peroxisome proliferator-activated receptor-alpha stimulates both differentiation and fatty acid oxidation in adipocytes

    Tsuyoshi Goto;Joo-Young Lee;Aki Teraminami;Yong-Il Kim

  • Overexpression and Ribozyme-mediated Targeting of Transcriptional Coactivators CREB-binding Protein and p300 Revealed Their Indispensable Roles in Adipocyte Differentiation through the Regulation of Peroxisome Proliferator-activated Receptor γ

    Nobuyuki Takahashi;Teruo Kawada;Takayuki Yamamoto;Tsuyoshi Goto

  • Fish oil intake induces UCP1 upregulation in brown and white adipose tissue via the sympathetic nervous system.

    Minji Kim;Tsuyoshi Goto;Rina Yu;Kunitoshi Uchida

  • Triiodothyronine induces UCP-1 expression and mitochondrial biogenesis in human adipocytes.

    Joo-Young Lee;Nobuyuki Takahashi;Midori Yasubuchi;Young-Il Kim

  • 6-Shogaol and 6-gingerol, the pungent of ginger, inhibit TNF-α mediated downregulation of adiponectin expression via different mechanisms in 3T3-L1 adipocytes

    Yasuka Isa;Yuri Miyakawa;Masayoshi Yanagisawa;Tsuyoshi Goto

  • Inhibitory effect of naringenin chalcone on inflammatory changes in the interaction between adipocytes and macrophages.

    Shizuka Hirai;Young-II Kim;Tsuyoshi Goto;Min-Sook Kang

  • Diosgenin present in fenugreek improves glucose metabolism by promoting adipocyte differentiation and inhibiting inflammation in adipose tissues.

    Taku Uemura;Shizuka Hirai;Noriko Mizoguchi;Tsuyoshi Goto

  • Diosgenin, the Main Aglycon of Fenugreek, Inhibits LXRα Activity in HepG2 Cells and Decreases Plasma and Hepatic Triglycerides in Obese Diabetic Mice

    Taku Uemura;Tsuyoshi Goto;Min‑Sook Kang;Noriko Mizoguchi

  • Macrophage infiltration into obese adipose tissues suppresses the induction of UCP1 level in mice.

    Tomoya Sakamoto;Takahiro Nitta;Koji Maruno;Yu-Sheng Yeh

  • Quercetin Protects against Obesity-Induced Skeletal Muscle Inflammation and Atrophy

    Ngoc Hoan Le;Chu Sook Kim;Taesun Park;Jung Han Yoon Park

  • Inflammation induced by RAW macrophages suppresses UCP1 mRNA induction via ERK activation in 10T1/2 adipocytes.

    Tomoya Sakamoto;Nobuyuki Takahashi;Yuri Sawaragi;Supaporn Naknukool

  • Tiliroside, a glycosidic flavonoid, ameliorates obesity-induced metabolic disorders via activation of adiponectin signaling followed by enhancement of fatty acid oxidation in liver and skeletal muscle in obese–diabetic mice

    Tsuyoshi Goto;Aki Teraminami;Joo-Young Lee;Kana Ohyama

  • Bixin regulates mRNA expression involved in adipogenesis and enhances insulin sensitivity in 3T3-L1 adipocytes through PPARγ activation

    Nobuyuki Takahashi;Tsuyoshi Goto;Aki Taimatsu;Kahori Egawa

  • Citrus auraptene acts as an agonist for PPARs and enhances adiponectin production and MCP-1 reduction in 3T3-L1 adipocytes.

    Kayo Kuroyanagi;Min-Sook Kang;Tsuyoshi Goto;Shizuka Hirai

  • Quercetin reduces obesity-induced hepatosteatosis by enhancing mitochondrial oxidative metabolism via heme oxygenase-1

    Chu Sook Kim;Yoonhee Kwon;Suck Young Choe;Sun Myung Hong

  • Functional Food Targeting the Regulation of Obesity-Induced Inflammatory Responses and Pathologies

    Shizuka Hirai;Nobuyuki Takahashi;Tsuyoshi Goto;Shan Lin

  • Phytol directly activates peroxisome proliferator-activated receptor α (PPARα) and regulates gene expression involved in lipid metabolism in PPARα-expressing HepG2 hepatocytes

    Tsuyoshi Goto;Nobuyuki Takahashi;Sota Kato;Kahori Egawa

Frequent Co-Authors

Teruo Kawada
Teruo Kawada Kyoto University
Rina Yu
Rina Yu University of Ulsan
Makoto Tominaga
Makoto Tominaga National Institutes of Natural Sciences
Daisuke Shibata
Daisuke Shibata Kyoto University
Hiroyasu Inoue
Hiroyasu Inoue Nara Women's University
Tohru Fushiki
Tohru Fushiki Kyoto University
Jun Ogawa
Jun Ogawa Kyoto University
Myung-Sook Choi
Myung-Sook Choi Kyungpook National University
Koh Aoki
Koh Aoki Osaka Metropolitan University
Nobuya Inagaki
Nobuya Inagaki Kyoto University

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