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Biology and Biochemistry

D-Index
67
Citations
33294
World Ranking
8036
National Ranking
3644

Overview

Shingo Kajimura is a researcher affiliated with Beth Israel Deaconess Medical Center in the United States. Their work primarily focuses on the intersection of medicine and biochemistry, genetics, and molecular biology, with significant contributions in the physiology and molecular biology subfields.

The core topics explored by Shingo Kajimura include adipose tissue and metabolism, mitochondrial function and pathology, and adipokines, inflammation, and metabolic diseases. Additional research interests encompass lipid metabolism and biosynthesis, studies on Trypanosoma species, diet and metabolism, and cancer-related hypoxia and metabolism.

Research by Kajimura has been published in a range of scientific venues, with frequent contributions to:

  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Metabolism
  • Nature Metabolism
  • SSRN Electronic Journal

Some of their recent papers include:

  • The cellular and functional complexity of thermogenic fat, 2021, Nature Reviews Molecular Cell Biology
  • CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling, 2020, Cell
  • Bacteroides spp. promotes branched-chain amino acid catabolism in brown fat and inhibits obesity, 2021, iScience
  • Post-translational control of beige fat biogenesis by PRDM16 stabilization, 2022, Nature
  • Adipose Tissue Remodeling in Pathophysiology, 2022, Annual Review of Pathology Mechanisms of Disease

Kajimura frequently collaborates with several researchers in related fields, including:

  • Anthony R.P. Verkerke
  • Christopher Auger
  • Takeshi Yoneshiro
  • Ichitaro Abe
  • Jin-Seon Yook

Their work predominantly contributes to advancing the understanding of adipose tissue biology, energy metabolism, and related molecular mechanisms that influence metabolic health and disease.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

    Pontus Boström;Jun Wu;Mark P. Jedrychowski;Anisha Korde

  • Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice

    Patrick Seale;Heather M. Conroe;Jennifer Estall;Shingo Kajimura

  • Transcriptional Control of Brown Fat Determination by PRDM16

    Patrick Seale;Shingo Kajimura;Wenli Yang;Sherry Chin

  • Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5

    Jang Hyun Choi;Alexander S. Banks;Jennifer L. Estall;Shingo Kajimura

  • Ablation of PRDM16 and Beige Adipose Causes Metabolic Dysfunction and a Subcutaneous to Visceral Fat Switch

    Paul Cohen;Julia D. Levy;Yingying Zhang;Andrea Frontini

  • Brown and Beige Fat: Physiological Roles beyond Heat Generation.

    Shingo Kajimura;Bruce M. Spiegelman;Patrick Seale

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • PPARγ agonists Induce a White-to-Brown Fat Conversion through Stabilization of PRDM16 Protein

    Haruya Ohno;Kosaku Shinoda;Bruce M. Spiegelman;Shingo Kajimura

  • Human BAT possesses molecular signatures that resemble beige/brite cells.

    Louis Z. Sharp;Kosaku Shinoda;Haruya Ohno;David W. Scheel

  • A Creatine-Driven Substrate Cycle Enhances Energy Expenditure and Thermogenesis in Beige Fat

    Lawrence Kazak;Edward T. Chouchani;Mark P. Jedrychowski;Brian K. Erickson

  • UCP1-independent signaling involving SERCA2b-mediated calcium cycling regulates beige fat thermogenesis and systemic glucose homeostasis.

    Kenji Ikeda;Qianqian Kang;Takeshi Yoneshiro;Joao Paulo Camporez

  • The Common and Distinct Features of Brown and Beige Adipocytes

    Kenji Ikeda;Pema Maretich;Shingo Kajimura

  • Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex

    Shingo Kajimura;Patrick Seale;Takuya Tomaru;Hediye Erdjument-Bromage

  • BCAA catabolism in brown fat controls energy homeostasis through SLC25A44.

    Takeshi Yoneshiro;Qiang Wang;Kazuki Tajima;Mami Matsushita

  • Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer

    Roman Camarda;Alicia Y Zhou;Rebecca A Kohnz;Sanjeev Balakrishnan

  • Transcriptional control of brown fat development.

    Shingo Kajimura;Patrick Seale;Bruce M. Spiegelman

  • Genetic and functional characterization of clonally derived adult human brown adipocytes

    Kosaku Shinoda;Ineke H N Luijten;Yutaka Hasegawa;Haemin Hong

  • Accumulation of succinate controls activation of adipose tissue thermogenesis.

    Evanna L. Mills;Kerry A. Pierce;Mark P. Jedrychowski;Ryan Garrity

  • The cellular and functional complexity of thermogenic fat

    Paul Cohen;Shingo Kajimura

Frequent Co-Authors

Bruce M. Spiegelman
Bruce M. Spiegelman Harvard University
Kenji Ikeda
Kenji Ikeda University of California, San Francisco
Patrick Seale
Patrick Seale University of Pennsylvania
Mark P. Jedrychowski
Mark P. Jedrychowski Harvard University
Juro Sakai
Juro Sakai University of Tokyo
Katsumi Aida
Katsumi Aida University of Tokyo
Evelina Gatti
Evelina Gatti Aix-Marseille University
Paul Cohen
Paul Cohen Rockefeller University
Maurizio Molinari
Maurizio Molinari Universita della Svizzera Italiana
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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