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Medicine

D-Index
103
Citations
54127
World Ranking
7208
National Ranking
240

Overview

Saverio Cinti is affiliated with Marche Polytechnic University in Italy and conducts research primarily within the field of medicine. Their work spans several subfields, including physiology, epidemiology, cardiology and cardiovascular medicine, infectious diseases, and surgery.

The main topics explored in their research focus on adipose tissue and metabolism, adipokines, inflammation, and metabolic diseases, cardiovascular disease and adiposity, COVID-19 clinical research studies, diet and metabolism studies, lipid metabolism and biosynthesis, and the long-term effects of COVID-19.

Their recent publications include a range of papers in high-impact journals, addressing diverse aspects of metabolic and cardiovascular health as well as adipose tissue biology. Notable examples are:

  • snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis, 2020, Nature
  • Bone marrow adipose tissue is a unique adipose subtype with distinct roles in glucose homeostasis, 2020, Nature Communications
  • Human epicardial adipose tissue expresses glucose-dependent insulinotropic polypeptide, glucagon, and glucagon-like peptide-1 receptors as potential targets of pleiotropic therapies, 2023, European Journal of Preventive Cardiology
  • Mammary gland adipocytes in lactation cycle, obesity and breast cancer, 2021, Reviews in Endocrine and Metabolic Disorders
  • Lipolysis-derived linoleic acid drives beige fat progenitor cell proliferation, 2022, Developmental Cell

The scientist collaborates frequently with several coauthors, including Antonio Giordano, Georgia Colleluori, Ilenia Severi, Angelica Di Vincenzo, and Enzo Nisoli. These collaborations reflect an interdisciplinary approach to understanding adipose tissue and metabolic regulation.

Saverio Cinti frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), International Journal of Obesity, Scientific Reports, Nature Communications, and Reviews in Endocrine and Metabolic Disorders. These journals cover topics related to metabolism, obesity, endocrine function, and broader biological sciences.

Best Publications

  • A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

    Pontus Boström;Jun Wu;Mark P. Jedrychowski;Anisha Korde

  • Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1

    Zhidan Wu;Pere Puigserver;Ulf Andersson;Chenyu Zhang

  • Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans

    Saverio Cinti;Grant Mitchell;Giorgio Barbatelli;Incoronata Murano

  • Defects in Adaptive Energy Metabolism with CNS-Linked Hyperactivity in PGC-1α Null Mice

    Jiandie Lin;Pei Hsuan Wu;Paul T. Tarr;Katrin S. Lindenberg

  • Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice

    Patrick Seale;Heather M. Conroe;Jennifer Estall;Shingo Kajimura

  • Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss.

    Raffaella Cancello;Corneliu Henegar;Nathalie Viguerie;Soraya Taleb

  • Ablation of PRDM16 and Beige Adipose Causes Metabolic Dysfunction and a Subcutaneous to Visceral Fat Switch

    Paul Cohen;Julia D. Levy;Yingying Zhang;Andrea Frontini

  • The Adipose Organ

    Saverio Cinti

  • The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation.

    G. Barbatelli;I. Murano;L. Madsen;L. Madsen;Q. Hao

  • βAR Signaling Required for Diet-Induced Thermogenesis and Obesity Resistance

    Eric S. Bachman;Harveen Dhillon;Chen Yu Zhang;Saverio Cinti

  • The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue

    Maria Cristina Zingaretti;Francesca Crosta;Alessandra Vitali;Mario Guerrieri

  • Transcriptional coactivator PGC-1α controls the energy state and contractile function of cardiac muscle

    Zoltan Arany;Huamei He;Jiandie Lin;Kirsten Hoyer

  • Dead adipocytes, detected as crown-like structures, are prevalent in visceral fat depots of genetically obese mice

    I. Murano;G. Barbatelli;V. Parisani;C. Latini

  • Occurrence of brown adipocytes in rat white adipose tissue: molecular and morphological characterization.

    B. Cousin;S. Cinti;M. Morroni;S. Raimbault

  • ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1

    Guenter Haemmerle;Tarek Moustafa;Gerald Woelkart;Sabrina Büttner

  • Multilocular fat cells in WAT of CL-316243-treated rats derive directly from white adipocytes.

    J. Himms-Hagen;A. Melnyk;M. C. Zingaretti;E. Ceresi

  • Human Metabolic Syndrome Resulting From Dominant-Negative Mutations in the Nuclear Receptor Peroxisome Proliferator-Activated Receptor-γ

    David B. Savage;Garry D. Tan;Carlo L. Acerini;Susan A. Jebb

  • Insulin Resistance in Morbid Obesity: Reversal With Intramyocellular Fat Depletion

    Aldo V. Greco;Gertrude Mingrone;Annalisa Giancaterini;Melania Manco

  • Distribution and Development of Brown Adipocytes in the Murine and Human Adipose Organ

    Andrea Frontini;Saverio Cinti

  • The adipose organ of obesity-prone C57BL/6J mice is composed of mixed white and brown adipocytes

    Alessandra Vitali;Incoronata Murano;Maria Cristina Zingaretti;Andrea Frontini

Frequent Co-Authors

Silvia Colucci
Silvia Colucci University of Luxembourg
Maria Grano
Maria Grano University of Bari Aldo Moro
Antonio Giordano
Antonio Giordano Temple University
Karsten Kristiansen
Karsten Kristiansen University of Copenhagen
Bruce M. Spiegelman
Bruce M. Spiegelman Harvard University
Lise Madsen
Lise Madsen University of Bergen
Antonio Vidal-Puig
Antonio Vidal-Puig University of Cambridge
Stephen O'Rahilly
Stephen O'Rahilly University of Cambridge
Andreu Palou
Andreu Palou University of the Balearic Islands
Ez-Zoubir Amri
Ez-Zoubir Amri Grenoble Alpes University

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