2026 Stephen O'Rahilly: Medicine Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Best Scientists	165	1038	953	103	93	630	109808
Medicine	166	604	552	73	67	629	112459

Research.com Recognitions

2026 - Research.com Medicine in United Kingdom Leader Award
2025 - Research.com Medicine in United Kingdom Leader Award
2016 - Member of the Royal Irish Academy
2013 - Baly Medal, Royal College of Physicians of London
2011 - Member of the National Academy of Sciences
2003 - Fellow of the Royal Society, United Kingdom
Member of the European Molecular Biology Organization (EMBO)
Member of the Association of American Physicians
Member of the European Molecular Biology Organization (EMBO)
Member of the Association of American Physicians
Member of the European Molecular Biology Organization (EMBO)
Member of the Association of American Physicians

Overview

Stephen O'Rahilly is affiliated with the University of Cambridge in the United Kingdom and specializes in medicine, with a significant focus on biochemistry, genetics, and molecular biology. Their work encompasses primary fields such as medicine and biochemistry, genetics & molecular biology, with subfields including physiology, molecular biology, genetics, rheumatology, and endocrine and autonomic systems.

The scientist's research concentrates on several main topics, involving GDF15 and related biomarkers, genetic associations and epidemiology, nutrition and health in aging, regulation of appetite and obesity, adipose tissue and metabolism, RNA modifications and cancer, and biochemical analysis and sensing techniques.

Stephen O'Rahilly has contributed to numerous publications in well-regarded venues. Frequent publication outlets include bioRxiv (Cold Spring Harbor Laboratory), The Journal of Clinical Endocrinology & Metabolism, Nature, Nature Metabolism, and Molecular Metabolism.

They have collaborated extensively with several frequent co-authors, including Sam Lockhart, John R. B. Perry, Brian Lam, Ken K. Ong, and Giles S.H. Yeo.

Notable recent papers authored or co-authored by Stephen O'Rahilly include:

Associations between body-mass index and COVID-19 severity in 6·9 million people in England: a prospective, community-based, cohort study, 2021, The Lancet Diabetes & Endocrinology
Mapping the proteo-genomic convergence of human diseases, 2021, Science
The energy balance model of obesity: beyond calories in, calories out, 2022, American Journal of Clinical Nutrition
GDF15: A Hormone Conveying Somatic Distress to the Brain, 2020, Endocrine Reviews
Cachexia: A systemic consequence of progressive, unresolved disease, 2023, Cell

Stephen O'Rahilly's work has been recognized by various honors and memberships, including:

Member of the Royal Irish Academy (2016)
Baly Medal, Royal College of Physicians of London (2013)
Member of the National Academy of Sciences (2011)
Fellow of the Royal Society, United Kingdom (2003)
Member of the Association of American Physicians
Member of the European Molecular Biology Organization (EMBO)

Best Publications

Congenital leptin deficiency is associated with severe early-onset obesity in humans

C T Montague;I S Farooqi;J P Whitehead;M A Soos

4012
Citations
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

Elizabeth K. Speliotes;Elizabeth K. Speliotes;Cristen J. Willer;Sonja I. Berndt;Keri L. Monda

3540
Citations
The GPR54 Gene as a Regulator of Puberty

Stephanie B. Seminara;Sophie Messager;Emmanouella E. Chatzidaki;Rosemary R. Thresher

3140
Citations
Effects of recombinant leptin therapy in a child with congenital leptin deficiency.

I S Farooqi;S A Jebb;G Langmack;E Lawrence

2429
Citations
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

Cristen J. Willer;Elizabeth K. Speliotes;Elizabeth K. Speliotes;Ruth J. F. Loos;Shengxu Li

2041
Citations
Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene.

I. Sadaf Farooqi;Julia M. Keogh;Giles S.H. Yeo;Emma J. Lank

2027
Citations
Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency

I. Sadaf Farooqi;Giuseppe Matarese;Graham M. Lord;Julia M. Keogh

1904
Citations
The Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate–Dependent Nucleic Acid Demethylase

Thomas Gerken;Christophe A. Girard;Yi-Chun Loraine Tung;Celia J. Webby

1865
Citations
Dominant negative mutations in human PPARγ associated with severe insulin resistance, diabetes mellitus and hypertension

I. Barroso;M. Gurnell;V. E. F. Crowley;M. Agostini

1717
Citations
A frameshift mutation in MC4R associated with dominantly inherited human obesity

G S Yeo;I S Farooqi;S Aminian;D J Halsall

1387
Citations
Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene

Robert S. Jackson;John W.M. Creemers;Shinya Ohagi;Marie-Laure Raffin-Sanson

1326
Citations
The genetic architecture of type 2 diabetes

Christian Fuchsberger;Christian Fuchsberger;Jason A. Flannick;Jason A. Flannick;Tanya M. Teslovich;Anubha Mahajan

1239
Citations
International Union of Pharmacology. LXI. Peroxisome Proliferator-Activated Receptors

Liliane Michalik;Johan Auwerx;Joel P. Berger;V. Krishna Chatterjee

1232
Citations
Genetics of body-weight regulation

Barsh Gs;Farooqi Is;O'Rahilly S

1219
Citations
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

E. K. Speliotes;C. J. Willer;S. I. Berndt;K. L. Monda

1200
Citations
Resistin / Fizz3 Expression in Relation to Obesity and Peroxisome Proliferator - Activated Receptor-γ Action in Humans

David B. Savage;Ciaran P. Sewter;Ellen S. Klenk;David G. Segal

1130
Citations
PPARγ and human metabolic disease

Robert K. Semple;V. Krishna K. Chatterjee;Stephen O’Rahilly

1119
Citations
The perils of portliness: causes and consequences of visceral adiposity.

C T Montague;S O'Rahilly

1041
Citations
TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproduction

A Kemal Topaloglu;Frank Reimann;Metin Guclu;Ayse Serap Yalin

1010
Citations
The UK10K project identifies rare variants in health and disease

Klaudia Walter;Josine L. Min;Jie Huang;Lucy Crooks

453
Citations

Frequent Co-Authors

Inês Barroso University of Exeter

I. Sadaf Farooqi University of Cambridge

Nicholas J. Wareham University of Cambridge

Robert K. Semple University of Edinburgh

Jian'an Luan University of Cambridge

Mark I. McCarthy Genentech

Antonio Vidal-Puig University of Cambridge

Paul W. Franks Lund University

Philippe Froguel Imperial College London

Ruth J. F. Loos University of Copenhagen

External Links

Personal website of Stephen O'Rahilly

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