World's Best Scientists 2026 revealed!
Leif Groop

Leif Groop

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Best Scientists
2025
Award Badge
Medicine
Sweden
2026

D-Index & Metrics

Best Scientists

D-Index
193
Citations
200903
World Ranking
370
National Ranking
5

Medicine

D-Index
192
Citations
205058
World Ranking
237
National Ranking
6

Research.com Recognitions

  • 2026 - Research.com Medicine in Sweden Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Medicine in Sweden Leader Award
  • 2023 - Research.com Medicine in Sweden Leader Award
  • 2022 - Research.com Medicine in Sweden Leader Award

Overview

Leif Groop is affiliated with Lund University in Sweden and has a research portfolio focused on medicine, particularly in genetics, endocrinology, diabetes, and molecular biology. Their work spans several main fields of study including Medicine and Biochemistry, Genetics and Molecular Biology, contributing extensively to these areas through numerous publications.

Their research includes significant contributions to subfields such as Genetics, Molecular Biology, Endocrinology, Diabetes and Metabolism, Surgery, and Physiology. These subfields reflect a focus on understanding complex biological systems and diseases related to metabolism and genetic function.

Groop's main topics of study emphasize pancreatic function and diabetes, diabetes and associated disorders, genetic associations and epidemiology, diabetes management and research, diabetes treatment and management, epigenetics and DNA methylation, as well as liver disease diagnosis and treatment. This demonstrates a broad interest in metabolic diseases and their genetic and physiological underpinnings.

Frequent co-authors with whom Groop has published include Emma Ahlqvist, Jaakko Tuomilehto, Rashmi B. Prasad, Paul W. Franks, and José C. Florez. This network indicates collaboration with researchers who specialize in diabetes and metabolic health.

Groop's work has appeared in a variety of scientific venues, particularly those that focus on biology and medicine. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Diabetologia
  • Nature Communications
  • Diabetes Care
  • UNC Libraries

Notable recent papers authored or co-authored by Groop are:

  • The mutational constraint spectrum quantified from variation in 141,456 humans, 2020, Nature
  • Subtypes of Type 2 Diabetes Determined From Clinical Parameters, 2020, Diabetes
  • Genetic analysis of obstructive sleep apnoea discovers a strong association with cardiometabolic health, 2020, European Respiratory Journal
  • Characterising the loss-of-function impact of 5' untranslated region variants in 15,708 individuals, 2020, Nature Communications
  • Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D, 2020, Nature Communications

Best Publications

  • PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

    Vamsi K Mootha;Cecilia M Lindgren;Cecilia M Lindgren;Karl-Fredrik Eriksson;Aravind Subramanian

  • Cardiovascular Morbidity and Mortality Associated With the Metabolic Syndrome

    Bo Isomaa;Peter Almgren;Tiinamaija Tuomi;Björn Forsén

  • Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes

    Siddhartha Jaiswal;Pierre Fontanillas;Jason Flannick;Jason Flannick;Alisa Manning

  • Biological, clinical and population relevance of 95 loci for blood lipids

    Tanya M. Teslovich;Kiran Musunuru;Albert V. Smith;Andrew C. Edmondson

  • Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

    Elizabeth K. Speliotes;Elizabeth K. Speliotes;Cristen J. Willer;Sonja I. Berndt;Keri L. Monda

  • A reference panel of 64,976 haplotypes for genotype imputation

    Shane McCarthy;Sayantan Das;Warren Kretzschmar;Olivier Delaneau

  • Discovery and refinement of loci associated with lipid levels

    Cristen J. Willer;Ellen M. Schmidt;Sebanti Sengupta;Gina M. Peloso;Gina M. Peloso;Gina M. Peloso

  • Genome-Wide Association Analysis Identifies Loci for Type 2 Diabetes and Triglyceride Levels

    Richa Saxena;Benjamin F. Voight;Valeriya Lyssenko;Noël P. Burtt

  • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

    Josée Dupuis;Josée Dupuis;Claudia Langenberg;Inga Prokopenko;Richa Saxena;Richa Saxena

  • Hundreds of variants clustered in genomic loci and biological pathways affect human height

    Hana Lango Allen;Karol Estrada;Guillaume Lettre;Sonja I. Berndt

  • The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes.

    David Altshuler;Joel N. Hirschhorn;Joel N. Hirschhorn;Joel N. Hirschhorn;Mia Klannemark;Cecilia M. Lindgren;Cecilia M. Lindgren

  • Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

    Georg B. Ehret;Georg B. Ehret;Georg B. Ehret;Patricia B. Munroe;Kenneth M. Rice;Murielle Bochud

  • Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

    E Zeggini;L J Scott;R Saxena;B F Voight

  • Defining the role of common variation in the genomic and biological architecture of adult human height

    Andrew R. Wood;Tonu Esko;Jian Yang;Sailaja Vedantam

  • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (vol 42, pg 105, 2010)

    J Dupuis;C Langenberg;I Prokopenko;R Saxena

  • Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

    Benjamin F. Voight;Benjamin F. Voight;Laura J. Scott;Valgerdur Steinthorsdottir;Andrew P. Morris

  • Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

    Andrew P Morris;Benjamin F Voight;Benjamin F Voight;Tanya M Teslovich;Teresa Ferreira

  • Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

    Cristen J. Willer;Elizabeth K. Speliotes;Elizabeth K. Speliotes;Ruth J. F. Loos;Shengxu Li

  • Type 2 diabetes mellitus.

    Ralph A. DeFronzo;Ele Ferrannini;Leif Groop;Robert R. Henry

  • Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (Nature Genetics (2010) 42 (105-116))

    Josée Dupuis;Claudia Langenberg;Inga Prokopenko;Richa Saxena

Frequent Co-Authors

Tiinamaija Tuomi
Tiinamaija Tuomi University of Helsinki
Valeriya Lyssenko
Valeriya Lyssenko University of Bergen
Joel N. Hirschhorn
Joel N. Hirschhorn Boston Children's Hospital
David Altshuler
David Altshuler Harvard University
Cecilia M. Lindgren
Cecilia M. Lindgren University of Oxford
Jaakko Tuomilehto
Jaakko Tuomilehto University of Helsinki
Michael Boehnke
Michael Boehnke University of Michigan–Ann Arbor
Paul W. Franks
Paul W. Franks Lund University
Kari Stefansson
Kari Stefansson deCODE Genetics (Iceland)

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