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Biology and Biochemistry

D-Index
53
Citations
9100
World Ranking
16263
National Ranking
6737

Overview

Stephen W. Schaffer is affiliated with the University of South Alabama in the United States. Their research spans the fields of biochemistry, genetics, molecular biology, and medicine, with focused subfields including cell biology, physiology, biochemistry, molecular biology, and pediatrics, perinatology, and child health.

The scientist's major research topics include aldose reductase and taurine, biochemical effects in animals, biochemical acid research studies, prenatal substance exposure effects, nitric oxide and endothelin effects, RNA research and splicing, and lipid metabolism and biosynthesis.

Frequent co-authors with whom they have collaborated are Takashi Ito, Shigeru Murakami, Chian Ju Jong, Sayuri Maeyama, and Khanh Hoang Nguyen.

Stephen W. Schaffer has contributed to several scholarly publications in various venues. These include:

  • The Role of Taurine in Mitochondria Health: More Than Just an Antioxidant (2021), published in Molecules
  • Differences Between Physiological and Pharmacological Actions of Taurine (2022), published in Advances in Experimental Medicine and Biology
  • N-Chlorotaurine Reduces the Lung and Systemic Inflammation in LPS-Induced Pneumonia in High Fat Diet-Induced Obese Mice (2022), published in Metabolites
  • Mechanisms Underlying Development of Taurine-Deficient Cardiomyopathy (2020), published in Hearts
  • Taurine suppresses liquid-liquid phase separation of lysozyme protein (2021), published in Amino Acids

The most frequent publication venues are Advances in Experimental Medicine and Biology, Molecules, Metabolites, Hearts, and Amino Acids.

Stephen W. Schaffer has also authored a book titled Taurine 12 published by Springer Nature in 2022.

Best Publications

  • Mechanism underlying the antioxidant activity of taurine: prevention of mitochondrial oxidant production

    Chian Ju Jong;Junichi Azuma;Stephen Schaffer

  • Physiological roles of taurine in heart and muscle

    Stephen W Schaffer;Chian Ju Jong;Ramila Kc;Junichi Azuma

  • Role of antioxidant activity of taurine in diabetes.

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  • Effects and Mechanisms of Taurine as a Therapeutic Agent.

    Stephen Schaffer;Ha Won Kim

  • Taurine depletion caused by knocking out the taurine transporter gene leads to cardiomyopathy with cardiac atrophy

    Takashi Ito;Yasushi Kimura;Yoriko Uozumi;Mika Takai

  • The potential usefulness of taurine on diabetes mellitus and its complications.

    Takashi Ito;Stephen W. Schaffer;Junichi Azuma

  • Free Radicals and Myocardial Ischemia

    Joe M. McCord;Ranjan S. Roy;Stephen W. Schaffer

  • Why is taurine cytoprotective

    Stephen Schaffer;Junichi Azuma;Kyoko Takahashi;Mahmood S Mozaffari

  • Effect of taurine on calcium paradox and ischemic heart failure

    J. H. Kramer;J. P. Chovan;S. W. Schaffer

  • Taurine inhibits apoptosis by preventing formation of the Apaf-1/caspase-9 apoptosome

    Tomoka Takatani;Kyoko Takahashi;Yoriko Uozumi;Eriko Shikata

  • Mitochondrial DNA damage triggers mitochondrial-superoxide generation and apoptosis

    Craig Ricci;Viktor Pastukh;Josh Leonard;Julio Turrens

  • Role of oxidative stress in diabetes-mediated vascular dysfunction: unifying hypothesis of diabetes revisited.

    Stephen W. Schaffer;Chian Ju Jong;Mahmood S Mozaffari

  • Metabolic dysfunction in diabetic cardiomyopathy.

    Michael Isfort;Sarah C. W. Stevens;Stephen Schaffer;Chian Ju Jong

  • Impaired energy metabolism of the taurine‑deficient heart.

    Stephen W. Schaffer;Kayoko Shimada-Takaura;Chian Ju Jong;Takashi Ito

  • Stimulation of the Na+/Ca2 +Exchanger by Phenylephrine, Angiotensin II and Endothelin 1

    Cherry Ballard;Stephen Schaffer

  • The Role of Taurine in Mitochondria Health: More Than Just an Antioxidant

    Chian Ju Jong;Priyanka Sandal;Stephen W. Schaffer

  • Cardiac and skeletal muscle abnormality in taurine transporter-knockout mice

    Takashi Ito;Shohei Oishi;Mika Takai;Yasushi Kimura

  • Non-insulin-dependent diabetes-induced defects in cardiac cellular calcium regulation.

    S. N. Allo;T. M. Lincoln;G. L. Wilson;F. J. Green

  • Effects of acidosis on myocardial contractility and metabolism.

    John R. Williamson;Brian Safer;Terrell Rich;Stephen Schaffer

  • Taurine prevents the ischemia-induced apoptosis in cultured neonatal rat cardiomyocytes through Akt/caspase-9 pathway.

    Tomoka Takatani;Kyoko Takahashi;Yoriko Uozumi;Takahisa Matsuda

Frequent Co-Authors

Junichi Azuma
Junichi Azuma Osaka University
Glenn L. Wilson
Glenn L. Wilson University of South Alabama
Yasushi Fujio
Yasushi Fujio Osaka University
James M. Downey
James M. Downey University of South Alabama
Michael V. Cohen
Michael V. Cohen University of South Alabama
Joe M. McCord
Joe M. McCord University of Colorado Denver
Masaru Okabe
Masaru Okabe Osaka University
J. Michael Wyss
J. Michael Wyss University of Alabama at Birmingham
Hitoshi Hashimoto
Hitoshi Hashimoto Osaka University
Daisuke Shibata
Daisuke Shibata Kyoto University

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