World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
7699
World Ranking
17333
National Ranking
7124

Overview

Horea Rus is affiliated with the University of Maryland, Baltimore in the United States. The scientist's research activities span multiple fields, with a primary focus on Medicine and Biochemistry, Genetics and Molecular Biology.

The main subfields that characterize their work include Neurology, Immunology, Molecular Biology, Pulmonary and Respiratory Medicine, and Pathology and Forensic Medicine.

Key research topics explored by Horea Rus cover areas such as Neuroinflammation and Neurodegeneration Mechanisms, Multiple Sclerosis Research Studies, Reproductive System and Pregnancy, RNA regulation and disease, Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis, Cell Adhesion Molecules Research, and Renal Diseases and Glomerulopathies.

The scientist has been active in publishing studies in various journals, frequently contributing to these venues:

  • Frontiers in Immunology
  • The Journal of Immunology
  • Clinical Immunology
  • Atherosclerosis
  • American Journal of Respiratory Cell and Molecular Biology

Among the recent papers authored or co-authored by Horea Rus are:

  • "Histone Deacetylase SIRT1 Mediates C5b-9-Induced Cell Cycle in Oligodendrocytes" (2020), published in Frontiers in Immunology
  • "Regulator of Cell Cycle Protein (RGCC/RGC-32) Protects against Pulmonary Fibrosis" (2021), published in American Journal of Respiratory Cell and Molecular Biology
  • "COVID, complement, and the brain" (2023), published in Frontiers in Immunology
  • "RGC-32' dual role in smooth muscle cells and atherogenesis" (2022), published in Clinical Immunology
  • "RGC-32 Regulates Generation of Reactive Astrocytes in Experimental Autoimmune Encephalomyelitis" (2021), published in Frontiers in Immunology

Frequent collaborations have been recorded with several co-authors, including:

  • Violeta Rus
  • Alexandru Tatomir
  • Tudor C. Badea
  • Sonia I. Vlaicu
  • Vinh Nguyen

Best Publications

  • Interleukin-6 and interleukin-8 protein and gene expression in human arterial atherosclerotic wall

    H.G. Rus;R. Vlaicu;F. Niculescu

  • The role of the complement system in innate immunity.

    Horea Rus;Cornelia Cudrici;Florin Niculescu

  • Membrane attack by complement: the assembly and biology of terminal complement complexes.

    Cosmin A. Tegla;Cosmin A. Tegla;Cornelia Cudrici;Snehal Patel;Richard Trippe

  • Continuous long-term immunomodulatory therapy in relapsing multiple sclerosis: results from the 15-year analysis of the US prospective open-label study of glatiramer acetate:

    C. Ford;AD Goodman;K. Johnson;N. Kachuck

  • Immunohistochemical localization of the terminal C5b-9 complement complex in human aortic fibrous plaque

    R. Vlaicu;F. Niculescu;H.G. Rus;A. Cristea

  • The voltage-gated potassium channel Kv1.3 is highly expressed on inflammatory infiltrates in multiple sclerosis brain

    Horea Rus;Carlos A. Pardo;Lina Hu;Erika Darrah

  • Persistent complement activation on tumor cells in breast cancer

    F Niculescu;H G Rus;M Retegan;R Vlaicu

  • Immunoglobulins and complement components in human aortic atherosclerotic intima

    R. Vlaicu;H.G. Rus;F. Niculescu;Anca Cristea

  • Sublytic complement attack induces cell cycle in oligodendrocytes.

    H G Rus;F Niculescu;M L Shin

  • C5b-9 Terminal Complement Complex Protects Oligodendrocytes from Death by Regulating Bad Through Phosphatidylinositol 3-Kinase/Akt Pathway

    Lucian Soane;Hyun-Jun Cho;Florin Niculescu;Horea Rus

  • Complement activation and atherosclerosis.

    Florin Niculescu;Horea Rus

  • Sublytic C5b-9 induces proliferation of human aortic smooth muscle cells Role of mitogen activated protein kinase and phosphatidylinositol 3-kinase

    Florin Niculescu;Tudor Badea;Horea Rus

  • Role of the C5b-9 complement complex in cell cycle and apoptosis.

    Horea G. Rus;Florin I. Niculescu;Moon L. Shin

  • Immunohistochemical localization of C5b-9, S-protein, C3d and apolipoprotein B in human arterial tissues with atherosclerosis

    F. Niculescu;H.G. Rus;R. Vlaicu

  • RGC-32 Increases p34CDC2 Kinase Activity and Entry of Aortic Smooth Muscle Cells into S-phase

    Tudor Badea;Florin Niculescu;Lucian Soane;Matthew Fosbrink

  • The role of complement activation in atherosclerosis

    Florin Niculescu;Horea Rus

  • Inhibition of oligodendrocyte apoptosis by sublytic C5b-9 is associated with enhanced synthesis of bcl-2 and mediated by inhibition of caspase-3 activation.

    Lucian Soane;Horea Rus;Florin Niculescu;Moon L. Shin

  • Cell cycle-dependent phosphorylation of the RUNX2 transcription factor by cdc2 regulates endothelial cell proliferation.

    Meng Qiao;Paul Shapiro;Matthew Fosbrink;Horea Rus

  • C5b-9-induced Endothelial Cell Proliferation and Migration Are Dependent on Akt Inactivation of Forkhead Transcription Factor FOXO1

    Matthew Fosbrink;Florin Niculescu;Violeta Rus;Moon L. Shin

  • Activation of Ras and mitogen-activated protein kinase pathway by terminal complement complexes is G protein dependent.

    F Niculescu;H Rus;T van Biesen;M L Shin

Frequent Co-Authors

Moon L. Shin
Moon L. Shin University of Maryland, Baltimore
Cedric S. Raine
Cedric S. Raine Albert Einstein College of Medicine
Peter A. Calabresi
Peter A. Calabresi Johns Hopkins University School of Medicine
Robert P. Lisak
Robert P. Lisak Wayne State University
Manuel F. Casanova
Manuel F. Casanova University of South Carolina
Anne Nicholson-Weller
Anne Nicholson-Weller Beth Israel Deaconess Medical Center
Dafin F. Muresanu
Dafin F. Muresanu Iuliu Hațieganu University of Medicine and Pharmacy
Heike Wulff
Heike Wulff University of California, Davis
Paula M. Pitha
Paula M. Pitha Johns Hopkins University
Rakesh Kumar
Rakesh Kumar The University of Texas MD Anderson Cancer Center

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