What is he best known for?
The fields of study he is best known for:
- Gene
- Internal medicine
- Immune system
Seppo Meri mostly deals with Complement system, Alternative complement pathway, Factor H, Biochemistry and Molecular biology.
His Complement system research incorporates elements of Microbiology and Cell biology.
His Alternative complement pathway research is multidisciplinary, incorporating perspectives in Macular degeneration, Recombinant DNA, Binding site and C-reactive protein.
His research integrates issues of Complement factor I, Sialic acid and Complement factor B in his study of Factor H.
His Biochemistry study combines topics from a wide range of disciplines, such as iC3b and Complement C3d.
His work carried out in the field of Molecular biology brings together such families of science as Cell culture, A549 cell, Transfection, Heparin and CD46.
His most cited work include:
- Human protectin (CD59), an 18,000-20,000 MW complement lysis restricting factor, inhibits C5b-8 catalysed insertion of C9 into lipid bilayers. (437 citations)
- Discrimination between activators and nonactivators of the alternative pathway of complement: regulation via a sialic acid/polyanion binding site on factor H. (364 citations)
- The complement regulator factor H binds to the surface protein OspE of Borrelia burgdorferi. (333 citations)
What are the main themes of his work throughout his whole career to date?
The scientist’s investigation covers issues in Complement system, Immunology, Alternative complement pathway, Factor H and Microbiology.
His Complement system research includes themes of Inflammation and Cell biology.
The Alternative complement pathway study combines topics in areas such as Complement factor B, Biochemistry, Binding site, iC3b and C-reactive protein.
His studies in Factor H integrate themes in fields like Molecular biology, Complement factor I and Recombinant DNA.
His Microbiology research is multidisciplinary, incorporating elements of Complement inhibitor, Bacterial outer membrane, Virulence and Virology.
His CD59 research focuses on subjects like CD46, which are linked to Decay-accelerating factor.
He most often published in these fields:
- Complement system (43.98%)
- Immunology (40.87%)
- Alternative complement pathway (24.69%)
What were the highlights of his more recent work (between 2014-2021)?
- Immunology (40.87%)
- Complement system (43.98%)
- Alternative complement pathway (24.69%)
In recent papers he was focusing on the following fields of study:
Seppo Meri spends much of his time researching Immunology, Complement system, Alternative complement pathway, Immune system and Inflammation.
As part of the same scientific family, Seppo Meri usually focuses on Complement system, concentrating on Cell biology and intersecting with Pentraxins.
His work deals with themes such as Atypical hemolytic uremic syndrome, Complement factor B, Factor H and Endocrinology, which intersect with Alternative complement pathway.
His biological study spans a wide range of topics, including Sialic acid, Biochemistry, iC3b, Complement membrane attack complex and C-reactive protein.
His Immune system study is mostly concerned with CD46 and Classical complement pathway.
His specific area of interest is Microbiology, where he studies Streptococcus pneumoniae.
Between 2014 and 2021, his most popular works were:
- Pentraxins in the activation and regulation of innate immunity (54 citations)
- Disturbed sialic acid recognition on endothelial cells and platelets in complement attack causes atypical hemolytic uremic syndrome (50 citations)
- Self-nonself discrimination by the complement system. (46 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Internal medicine
- Immune system
His primary areas of study are Complement system, Immunology, Immune system, Alternative complement pathway and Cell biology.
His studies deal with areas such as Inflammation, Innate immune system and Microbiology as well as Complement system.
His study in Alternative complement pathway is interdisciplinary in nature, drawing from both Insulin receptor, Adipose tissue macrophages, Complement factor B, Adipose tissue and Adipokine.
His research in Cell biology intersects with topics in Receptor and PTX3, Pentraxins.
His Factor H research integrates issues from Sialic acid, Biochemistry, iC3b and C3-convertase.
His Biochemistry study combines topics in areas such as Complement control protein and Phagocytosis.
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