2023 - Research.com Microbiology in Finland Leader Award
2022 - Research.com Microbiology in Finland Leader Award
Seppo Meri mostly deals with Complement system, Alternative complement pathway, Factor H, Biochemistry and Molecular biology. His Complement system research incorporates elements of Microbiology and Cell biology. His Alternative complement pathway research is multidisciplinary, incorporating perspectives in Macular degeneration, Recombinant DNA, Binding site and C-reactive protein.
His research integrates issues of Complement factor I, Sialic acid and Complement factor B in his study of Factor H. His Biochemistry study combines topics from a wide range of disciplines, such as iC3b and Complement C3d. His work carried out in the field of Molecular biology brings together such families of science as Cell culture, A549 cell, Transfection, Heparin and CD46.
The scientist’s investigation covers issues in Complement system, Immunology, Alternative complement pathway, Factor H and Microbiology. His Complement system research includes themes of Inflammation and Cell biology. The Alternative complement pathway study combines topics in areas such as Complement factor B, Biochemistry, Binding site, iC3b and C-reactive protein.
His studies in Factor H integrate themes in fields like Molecular biology, Complement factor I and Recombinant DNA. His Microbiology research is multidisciplinary, incorporating elements of Complement inhibitor, Bacterial outer membrane, Virulence and Virology. His CD59 research focuses on subjects like CD46, which are linked to Decay-accelerating factor.
Seppo Meri spends much of his time researching Immunology, Complement system, Alternative complement pathway, Immune system and Inflammation. As part of the same scientific family, Seppo Meri usually focuses on Complement system, concentrating on Cell biology and intersecting with Pentraxins. His work deals with themes such as Atypical hemolytic uremic syndrome, Complement factor B, Factor H and Endocrinology, which intersect with Alternative complement pathway.
His biological study spans a wide range of topics, including Sialic acid, Biochemistry, iC3b, Complement membrane attack complex and C-reactive protein. His Immune system study is mostly concerned with CD46 and Classical complement pathway. His specific area of interest is Microbiology, where he studies Streptococcus pneumoniae.
His primary areas of study are Complement system, Immunology, Immune system, Alternative complement pathway and Cell biology. His studies deal with areas such as Inflammation, Innate immune system and Microbiology as well as Complement system. His study in Alternative complement pathway is interdisciplinary in nature, drawing from both Insulin receptor, Adipose tissue macrophages, Complement factor B, Adipose tissue and Adipokine.
His research in Cell biology intersects with topics in Receptor and PTX3, Pentraxins. His Factor H research integrates issues from Sialic acid, Biochemistry, iC3b and C3-convertase. His Biochemistry study combines topics in areas such as Complement control protein and Phagocytosis.
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Human protectin (CD59), an 18,000-20,000 MW complement lysis restricting factor, inhibits C5b-8 catalysed insertion of C9 into lipid bilayers.
S Meri;B P Morgan;A Davies;R H Daniels.
Discrimination between activators and nonactivators of the alternative pathway of complement: regulation via a sialic acid/polyanion binding site on factor H.
Seppo Meri;Michael K. Pangburn.
Proceedings of the National Academy of Sciences of the United States of America (1990)
Membranoproliferative Glomerulonephritis Type II (Dense Deposit Disease): An Update
Gerald B. Appel;H. Terence Cook;Gregory Hageman;J. Charles Jennette.
Journal of The American Society of Nephrology (2005)
The complement regulator factor H binds to the surface protein OspE of Borrelia burgdorferi.
Jens Hellwage;Taru Susanna Meri;Tero Heikkilä;Antti Alitalo.
Journal of Biological Chemistry (2001)
Complement Activation after Oxidative Stress : Role of the Lectin Complement Pathway
Charles D. Collard;Antti Väkevä;Margaret A. Morrissey;Azin Agah.
American Journal of Pathology (2000)
Intracellular Complement Activation Sustains T Cell Homeostasis and Mediates Effector Differentiation
M. Kathryn Liszewski;Martin Kolev;Gaelle Le Friec;Marilyn Leung.
Mutations in factor H reduce binding affinity to C3b and heparin and surface attachment to endothelial cells in hemolytic uremic syndrome
Tamara Manuelian;Jens Hellwage;Seppo Meri;Jessica Caprioli.
Journal of Clinical Investigation (2003)
Rituximab (anti-CD20) therapy of B-cell lymphomas: direct complement killing is superior to cellular effector mechanisms.
A Harjunpää;S Junnikkala;S Meri.
Scandinavian Journal of Immunology (2000)
Molecular genetic characterization of the Fennoscandian cervid strain, a new genotypic group (G10) of Echinococcus granulosus
A Lavikainen;M J Lehtinen;T Meri;V Hirvelä-Koski.
Factor H family proteins: on complement, microbes and human diseases.
P. F. Zipfel;C. Skerka;J. Hellwage;S. T. Jokiranta.
Biochemical Society Transactions (2001)
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