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T. Sakari Jokiranta

T. Sakari Jokiranta

D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
10251
World Ranking
16641
National Ranking
120

Overview

T. Sakari Jokiranta is affiliated with the University of Helsinki in Finland. Their research primarily spans the fields of Medicine as well as Biochemistry, Genetics, and Molecular Biology. Within these domains, their work focuses on several subfields including Rheumatology, Infectious Diseases, Immunology, Genetics, and Epidemiology.

Their recent scientific contributions address various medical topics, such as Escherichia coli research studies, viral gastroenteritis research and epidemiology, inflammatory bowel disease, spondyloarthritis studies and treatments, rheumatoid arthritis research and therapies, autoimmune and inflammatory disorders research, and urinary tract infections management.

Key recent papers authored or co-authored by T. Sakari Jokiranta include:

  • Safety and immunogenicity of ETVAX®, an oral inactivated vaccine against enterotoxigenic Escherichia coli diarrhoea: a double-blinded, randomized, placebo-controlled trial amongst Finnish travellers to Benin, West Africa (2023, Journal of Travel Medicine)
  • Autoantibodies Against the Complement Regulator Factor H in the Serum of Patients With Neuromyelitis Optica Spectrum Disorder (2021, Frontiers in Immunology)
  • Assessing the Need for Multiplex and Multifunctional Tick-Borne Disease Test in Routine Clinical Laboratory Samples from Lyme Disease and Febrile Patients with a History of a Tick Bite (2021, Tropical Medicine and Infectious Disease)
  • Immunogenicity of subcutaneous TNF inhibitors and its clinical significance in real-life setting in patients with spondyloarthritis (2021, Rheumatology International)
  • Short interruptions of TNF-inhibitor treatment can be associated with treatment failure in patients with immune-mediated diseases (2022, Autoimmunity)

T. Sakari Jokiranta frequently collaborates with several coauthors, including:

  • Anu Kantele
  • Anu Patjas
  • Nils Carlin
  • Taina Sipponen
  • Tea Lamberg

Their work has been published in a variety of scientific journals, prominent among these:

  • Journal of Travel Medicine
  • Frontiers in Immunology
  • Scandinavian Journal of Gastroenterology
  • Tropical Medicine and Infectious Disease
  • Rheumatology International

Best Publications

  • New Approaches to the Treatment of Dense Deposit Disease

    Richard J.H. Smith;Jessy Alexander;Paul N. Barlow;Marina Botto

  • Y402H polymorphism of complement factor H affects binding affinity to C-reactive protein

    Matti Laine;Hanna Jarva;Hanna Jarva;Sanna Seitsonen;Karita Haapasalo

  • HUS and atypical HUS

    T. Sakari Jokiranta

  • Immune evasion of the human pathogen Pseudomonas aeruginosa: elongation factor Tuf is a factor H and plasminogen binding protein.

    Anja Kunert;Josephine Losse;Christin Gruszin;Michael Hühn

  • Dual interaction of factor H with C3d and glycosaminoglycans in host–nonhost discrimination by complement

    Tommi Kajander;Markus Juhana Lehtinen;Satu Hyvärinen;Arnab Bhattacharjee

  • Review of cases with the emerging fifth human malaria parasite, Plasmodium knowlesi.

    Anu Kantele;Anu Kantele;T. Sakari Jokiranta

  • Binding of the Long Pentraxin PTX3 to Factor H: Interacting Domains and Function in the Regulation of Complement Activation

    Livija Deban;Hanna Jarva;Hanna Jarva;Markus J. Lehtinen;Barbara Bottazzi

  • The factor H protein family.

    Peter F Zipfel;T.Sakari Jokiranta;Jens Hellwage;Vesa Koistinen

  • Complement Evasion by Borrelia burgdorferi: Serum-Resistant Strains Promote C3b Inactivation

    Antti Alitalo;Taru Susanna Meri;Lasse Rämö;T. Sakari Jokiranta

  • Structure of complement factor H carboxyl-terminus reveals molecular basis of atypical haemolytic uremic syndrome

    T Sakari Jokiranta;Veli-Pekka Jaakola;Markus J Lehtinen;Maria Pärepalo

  • A common site within factor H SCR 7 responsible for binding heparin, C-reactive protein and streptococcal M protein.

    Eleni Giannakis;T. Sakari Jokiranta;Dean A. Male;Shoba Ranganathan

  • Functional properties of complement factor H-related proteins FHR-3 and FHR-4: binding to the C3d region of C3b and differential regulation by heparin.

    Jens Hellwage;T.Sakari Jokiranta;Vesa Koistinen;Outi Vaarala

  • The C‐terminus of complement regulator Factor H mediates target recognition: evidence for a compact conformation of the native protein

    M. Oppermann;T. Manuelian;M. Józsi;E. Brandt

  • De novo gene conversion in the RCA gene cluster (1q32) causes mutations in complement factor H associated with atypical hemolytic uremic syndrome

    Stefan Heinen;Pilar Sanchez-Corral;Michael S Jackson;Lisa Strain

  • Complement analysis in the 21st century.

    Tom Eirik Mollnes;Tom Eirik Mollnes;T. Sakari Jokiranta;Lennart Truedsson;Bo Nilsson

  • Exceptional Resistance of Human H2 Glioblastoma Cells to Complement-Mediated Killing by Expression and Utilization of Factor H and Factor H-Like Protein 1

    S. Junnikkala;T. S. Jokiranta;M. A. Friese;H. Jarva

  • Complement C3b/C3d and Cell Surface Polyanions Are Recognized by Overlapping Binding Sites on the Most Carboxyl-Terminal Domain of Complement Factor H

    Jells Hellwage;T. Sakari Jokiranta;Manuel A. Friese;Tobias U. Wolk

  • Complement resistance mechanisms of streptococci.

    Hanna Jarva;T.Sakari Jokiranta;Reinhard Würzner;Seppo Meri

  • FHL-1/reconectin and factor H: two human complement regulators which are encoded by the same gene are differently expressed and regulated

    Manuel A Friese;Jens Hellwage;T.Sakari Jokiranta;Seppo Meri

  • Analysis of the recognition mechanism of the alternative pathway of complement by monoclonal anti‐factor H antibodies: evidence for multiple interactions between H and surface bound C3b

    T. Sakari Jokiranta;Peter F. Zipfel;Juha Hakulinen;Sabine Kühn

Frequent Co-Authors

Seppo Meri
Seppo Meri University of Helsinki
Peter F. Zipfel
Peter F. Zipfel Friedrich Schiller University Jena
Juha Kere
Juha Kere Karolinska Institute
Mihály Józsi
Mihály Józsi Eötvös Loránd University
David L. Gordon
David L. Gordon Flinders Medical Centre
Zoltán Prohászka
Zoltán Prohászka Semmelweis University
Jos A. G. van Strijp
Jos A. G. van Strijp Utrecht University
Johan van der Vlag
Johan van der Vlag Radboud University

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