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Immunology

D-Index
65
Citations
14938
World Ranking
2851
National Ranking
255

Overview

Matthew C. Pickering is affiliated with Imperial College London in the United Kingdom and has contributed extensively to research within the fields of Medicine and Immunology and Microbiology. Their scholarly output encompasses a diverse array of topics, with a focus on immunological mechanisms and renal pathology.

Their main subfields of study include Immunology, Nephrology, Hematology, Infectious Diseases, and Molecular Biology.

  • Immunology
  • Nephrology
  • Hematology
  • Infectious Diseases
  • Molecular Biology

Key topics Matthew C. Pickering has explored in their research are:

  • Complement system in diseases
  • Renal Diseases and Glomerulopathies
  • COVID-19 Clinical Research Studies
  • Blood Coagulation and Thrombosis Mechanisms
  • Systemic Lupus Erythematosus Research
  • Phagocytosis and Immune Regulation
  • Platelet Disorders and Treatments

Their recent publications illustrate a focus on kidney diseases, immune system regulation, and infectious disease outcomes. Notable papers include:

  • "High Prevalence of Asymptomatic COVID-19 Infection in Hemodialysis Patients Detected Using Serologic Screening," 2020, Journal of the American Society of Nephrology
  • "Type I interferons affect the metabolic fitness of CD8+ T cells from patients with systemic lupus erythematosus," 2021, Nature Communications
  • "Complement activation in IgA nephropathy," 2021, Seminars in Immunopathology
  • "The role of complement in kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference," 2024, Kidney International
  • "O- and N-Glycosylation of Serum Immunoglobulin A is Associated with IgA Nephropathy and Glomerular Function," 2021, Journal of the American Society of Nephrology

Matthew C. Pickering publishes frequently in several specialized journals, with major contributions to the following venues:

  • Journal of the American Society of Nephrology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Kidney International Reports
  • Frontiers in Immunology
  • Kidney International

The scientist commonly collaborates with a core group of co-authors, which includes:

  • Marina Botto
  • Nicholas Medjeral-Thomas
  • Talat H. Malik
  • David Thomas
  • Stephen P. McAdoo

This body of work reflects an integrative approach to understanding immune mechanisms in relation to kidney disease and systemic autoimmune conditions, as well as the implications of infectious diseases like COVID-19 on vulnerable patient populations.

Best Publications

  • Atypical hemolytic uremic syndrome and C3 glomerulopathy: conclusions from a “Kidney Disease: Improving Global Outcomes” (KDIGO) Controversies Conference

    Timothy H.J. Goodship;H. Terence Cook;Fadi Fakhouri;Fernando C. Fervenza

  • C3 glomerulopathy: consensus report

    Matthew C. Pickering;Vivette D. D'agati;Carla M. Nester;Richard J. Smith

  • Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H

    Matthew C. Pickering;H. Terence Cook;Joanna Warren;Anne E. Bygrave

  • Intracellular Complement Activation Sustains T Cell Homeostasis and Mediates Effector Differentiation

    M. Kathryn Liszewski;Martin Kolev;Gaelle Le Friec;Marilyn Leung

  • Systemic lupus erythematosus, complement deficiency, and apoptosis.

    M C Pickering;M Botto;P R Taylor;P J Lachmann

  • C3 glomerulopathy: a new classification

    Fadi Fakhouri;Véronique Frémeaux-Bacchi;Laure-Hélène Noël;H Terence Cook

  • C3 glomerulopathy — understanding a rare complement-driven renal disease

    Richard J.H. Smith;Gerald B. Appel;Anna M. Blom;H. Terence Cook

  • Identification of a mutation in complement factor H-related protein 5 in patients of Cypriot origin with glomerulonephritis

    Daniel P Gale;Daniel P Gale;Elena Goicoechea de Jorge;H Terence Cook;Rubén Martinez-Barricarte

  • Spontaneous hemolytic uremic syndrome triggered by complement factor H lacking surface recognition domains

    Matthew C. Pickering;Elena Goicoechea de Jorge;Rubén Martinez-Barricarte;Sergio Recalde

  • Atypical aHUS: State of the art.

    Carla M. Nester;Thomas Barbour;Santiago Rodriquez de Cordoba;Marie Agnes Dragon-Durey

  • Complement in human diseases: Lessons from complement deficiencies.

    Marina Botto;Michael Kirschfink;Paolo Macor;Matthew C. Pickering

  • C1q deficiency and autoimmunity: the effects of genetic background on disease expression.

    Daniel A. Mitchell;Matthew C. Pickering;Joanna Warren;Liliane Fossati-Jimack

  • The complement system as a potential therapeutic target in rheumatic disease

    Leendert A. Trouw;Matthew C. Pickering;Anna M. Blom

  • Translational Mini‐Review Series on Complement Factor H: Renal diseases associated with complement factor H: novel insights from humans and animals

    M. C. Pickering;H. T. Cook

  • Links between complement abnormalities and systemic lupus erythematosus

    M. C. Pickering;M. J. Walport

  • Prevention of C5 activation ameliorates spontaneous and experimental glomerulonephritis in factor H-deficient mice

    M. C. Pickering;J. Warren;K. L. Rose;F. Carlucci

  • Circulating complement factor H-related proteins 1 and 5 correlate with disease activity in IgA nephropathy.

    Nicholas R. Medjeral-Thomas;Hannah J. Lomax-Browne;Hannah Beckwith;Michelle Willicombe

  • Complement Factor H Inhibits CD47-Mediated Resolution of Inflammation

    Bertrand Calippe;Sebastien Augustin;Fanny Beguier;Hugo Charles-Messance

  • High Prevalence of Asymptomatic COVID-19 Infection in Hemodialysis Patients Detected Using Serologic Screening.

    Candice Clarke;Maria Prendecki;Amrita Dhutia;Mahrukh A Ali

  • P2X7 deficiency attenuates renal injury in experimental glomerulonephritis

    Simon R.J. Taylor;Clare M. Turner;James I. Elliott;John McDaid

  • C1q deficiency and autoimmunity: The effects of genetic background on disease expression

    DA Mitchell;HT Cook;M Botto;MJ Walport

Frequent Co-Authors

Marina Botto
Marina Botto Imperial College London
H. Terence Cook
H. Terence Cook Imperial College London
Mark Walport
Mark Walport Imperial College London
Susan M. Lea
Susan M. Lea University of Oxford
Claire L. Harris
Claire L. Harris Newcastle University
Richard J.H. Smith
Richard J.H. Smith University of Iowa
Santiago Rodríguez de Córdoba
Santiago Rodríguez de Córdoba Spanish National Research Council
David J. Kavanagh
David J. Kavanagh Queensland University of Technology
V. Michael Holers
V. Michael Holers University of Colorado Denver

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