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D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
14416
World Ranking
10748
National Ranking
4669

Overview

Brant E. Isakson is affiliated with the University of Virginia in the United States. Their research spans across several fields within biological sciences, with a primary focus on biochemistry, genetics, and molecular biology as well as medicine. The scientist has contributed extensively to subfields such as molecular biology, physiology, cardiology and cardiovascular medicine, cell biology, and neurology.

The research topics frequently addressed by Isakson include:

  • Connexins and lens biology
  • Nitric Oxide and Endothelin Effects
  • Heme Oxygenase-1 and Carbon Monoxide
  • Neuroscience of respiration and sleep
  • Erythrocyte Function and Pathophysiology
  • Cardiovascular Health and Disease Prevention
  • Cardiovascular, Neuropeptides, and Oxidative Stress Research

They have published a substantial number of papers in various venues known for life sciences and cardiovascular research. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The FASEB Journal
  • Physiology
  • American Journal of Physiology-Heart and Circulatory Physiology
  • Arteriosclerosis Thrombosis and Vascular Biology

Recent research articles authored by Brant E. Isakson include:

  • Capillary-associated microglia regulate vascular structure and function through PANX1-P2RY12 coupling in mice, 2021, Nature Communications
  • Red Blood Cell and Endothelial eNOS Independently Regulate Circulating Nitric Oxide Metabolites and Blood Pressure, 2021, Circulation
  • Guidelines for the measurement of vascular function and structure in isolated arteries and veins, 2021, American Journal of Physiology-Heart and Circulatory Physiology
  • Brain endothelial cell TRPA1 channels initiate neurovascular coupling, 2021, eLife
  • Local Peroxynitrite Impairs Endothelial Transient Receptor Potential Vanilloid 4 Channels and Elevates Blood Pressure in Obesity, 2020, Circulation

Collaboration is an integral part of Isakson's research. Frequent co-authors with significant joint publication counts include:

  • Scott R. Johnstone
  • Luke S. Dunaway
  • Melissa A. Luse
  • Miriam M. Cortese-Krott
  • Swapnil K. Sonkusare

Best Publications

  • KLF4 Dependent Phenotypic Modulation of SMCs Plays a Key Role inAtherosclerotic Plaque Pathogenesis

    Laura S. Shankman;Delphine Gomez;Olga A. Cherepanova;Morgan Salmon

  • Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis

    Faraaz B. Chekeni;Michael R. Elliott;Michael R. Elliott;Joanna K. Sandilos;Scott F. Walk;Scott F. Walk

  • Corrigendum: KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis.

    Laura S Shankman;Delphine Gomez;Olga A Cherepanova;Morgan Salmon

  • Identification of a Novel Macrophage Phenotype That Develops in Response to Atherogenic Phospholipids via Nrf2

    Alexandra Kadl;Akshaya K. Meher;Poonam R. Sharma;Monica Y. Lee

  • Red Blood Cell Function and Dysfunction: Redox Regulation, Nitric Oxide Metabolism, Anemia.

    Viktoria Kuhn;Lukas Diederich;T.C. Stevenson Keller;Christian M. Kramer

  • Mechanisms of ATP release and signalling in the blood vessel wall

    Alexander W. Lohman;Marie Billaud;Brant E. Isakson

  • Endothelial cell expression of haemoglobin α regulates nitric oxide signalling

    Adam C. Straub;Alexander W. Lohman;Marie Billaud;Scott R. Johnstone

  • Capillary-associated microglia regulate vascular structure and function through PANX1-P2RY12 coupling in mice.

    Kanchan Bisht;Kenneth A. Okojie;Kaushik Sharma;Dennis H. Lentferink

  • Pannexin1 Regulates α1-Adrenergic Receptor–Mediated Vasoconstriction

    Marie Billaud;Alexander W. Lohman;Adam C. Straub;Robin Looft-Wilson

  • Vascular Smooth Muscle Remodeling in Conductive and Resistance Arteries in Hypertension.

    Isola A.M. Brown;Lukas Diederich;Miranda E. Good;Leon J. DeLalio

  • Differentiating connexin hemichannels and pannexin channels in cellular ATP release

    Alexander W. Lohman;Brant E. Isakson

  • Pannexin 1 channels regulate leukocyte emigration through the venous endothelium during acute inflammation.

    Alexander W. Lohman;Igor L. Leskov;Joshua T. Butcher;Scott R. Johnstone

  • Compartmentalized Connexin 43 S-Nitrosylation/Denitrosylation Regulates Heterocellular Communication in the Vessel Wall

    Adam C. Straub;Marie Billaud;Scott R. Johnstone;Angela K. Best

  • Connexins: Gaps in Our Knowledge of Vascular Function

    Xavier F. Figueroa;Brant E. Isakson;Brian R. Duling

  • Heterocellular Contact at the Myoendothelial Junction Influences Gap Junction Organization

    Brant E. Isakson;Brian R. Duling

  • AXL-Mediated Productive Infection of Human Endothelial Cells by Zika Virus

    Shufeng Liu;Leon J. DeLalio;Brant E. Isakson;Tony T. Wang

  • Ca2+ and Inositol 1,4,5-Trisphosphate–Mediated Signaling Across the Myoendothelial Junction

    Brant E. Isakson;Susan I. Ramos;Brian R. Duling

  • Hypoxic pulmonary vasoconstriction requires connexin 40–mediated endothelial signal conduction

    Liming Wang;Jun Yin;Hannah T. Nickles;Hannes Ranke

  • Red Blood Cell and Endothelial eNOS Independently Regulate Circulating Nitric Oxide Metabolites and Blood Pressure.

    Francesca Leo;Tatsiana Suvorava;Sophia K. Heuser;Junjie Li

  • A molecular signature in the pannexin1 intracellular loop confers channel activation by the α1 adrenoreceptor in smooth muscle cells

    Marie Billaud;Yu-Hsin Chiu;Alexander W. Lohman;Thibaud Parpaite

Frequent Co-Authors

Kodi S. Ravichandran
Kodi S. Ravichandran University of Virginia
Norbert Leitinger
Norbert Leitinger University of Virginia
Michael Koval
Michael Koval Emory University
Douglas A. Bayliss
Douglas A. Bayliss University of Virginia
Dale W. Laird
Dale W. Laird University of Western Ontario
Benjamin Gaston
Benjamin Gaston Indiana University
Richard D. Minshall
Richard D. Minshall University of Illinois at Chicago
Avril V. Somlyo
Avril V. Somlyo University of Virginia
Malte Kelm
Malte Kelm Heinrich Heine University Düsseldorf
Paul D. Lampe
Paul D. Lampe Fred Hutchinson Cancer Research Center

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