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Biology and Biochemistry

D-Index
64
Citations
15298
World Ranking
9622
National Ranking
4249

Overview

Gerhard Dahl is affiliated with the University of Miami in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a particular emphasis on molecular biology. The scope of their work also extends to physiology, genetics, cardiology and cardiovascular medicine, and insect science.

They have contributed to several topics within these fields, including:

  • Connexins and lens biology
  • Ion channel regulation and function
  • Nicotinic acetylcholine receptors study
  • Biochemical effects in animals
  • Yersinia bacterium, plague, ectoparasites research
  • Heme oxygenase-1 and carbon monoxide
  • Cardiac electrophysiology and arrhythmias

Their recent publications highlight a focus on pannexin 1 channels and channel blockers, with studies spanning structural, chemical synthesis, and pharmacological evaluation perspectives. The most recent papers include:

  • Structural basis of ATP release and ion selectivity in Pannexin1 channels, 2025, published in bioRxiv (Cold Spring Harbor Laboratory)
  • Design, Synthesis and Pharmacological Evaluation of New Quinoline-Based Panx-1 Channel Blockers, 2023, International Journal of Molecular Sciences
  • New Panx-1 Blockers: Synthesis, Biological Evaluation and Molecular Dynamic Studies, 2022, International Journal of Molecular Sciences
  • Design and synthesis of the first indole-based blockers of Panx-1 channel, 2021, European Journal of Medicinal Chemistry
  • Structure versus function: Are new conformations of pannexin 1 yet to be resolved?, 2021, The Journal of General Physiology

The scientist frequently collaborates with several researchers, including Junjie Wang, Carsten Mim, Letizia Crocetti, Gabriella Guerrini, and Maria Paola Giovannoni. These collaborations have resulted in multiple publications exploring various aspects of molecular and cellular physiology.

Gerhard Dahl's work is regularly published in journals such as the International Journal of Molecular Sciences, The Journal of General Physiology, European Journal of Medicinal Chemistry, bioRxiv (Cold Spring Harbor Laboratory), and FEBS Journal, reflecting the interdisciplinary nature of their research.

Best Publications

  • Pannexin membrane channels are mechanosensitive conduits for ATP

    Li Bao;Silviu Locovei;Gerhard Dahl

  • Activation of human heat shock genes is accompanied by oligomerization, modification, and rapid translocation of heat shock transcription factor HSF1.

    R Baler;G Dahl;R Voellmy

  • Activation of pannexin 1 channels by ATP through P2Y receptors and by cytoplasmic calcium

    Silviu Locovei;Junjie Wang;Gerhard Dahl

  • The pannexin 1 channel activates the inflammasome in neurons and astrocytes.

    William R. Silverman;Juan Pablo de Rivero Vaccari;Silviu Locovei;Feng Qiu

  • Pannexin 1 in erythrocytes: function without a gap.

    Silviu Locovei;Li Bao;Gerhard Dahl

  • Pannexin1 is part of the pore forming unit of the P2X7 receptor death complex

    Silviu Locovei;Eliana Scemes;Feng Qiu;David C. Spray

  • Probenecid, a gout remedy, inhibits pannexin 1 channels.

    William Silverman;Silviu Locovei;Gerhard P Dahl

  • Pannexin 1: The Molecular Substrate of Astrocyte “Hemichannels”

    Rodolfo Iglesias;Gerhard Dahl;Feng Qiu;David C. Spray

  • Pannexin channels are not gap junction hemichannels

    Gina E. Sosinsky;Daniela Boassa;Rolf Dermietzel;Heather S. Duffy

  • Pannexin1 Channels Contain a Glycosylation Site That Targets the Hexamer to the Plasma Membrane

    Daniela Boassa;Cinzia Ambrosi;Feng Qiu;Gerhard Dahl

  • Pyroptotic neuronal cell death mediated by the AIM2 inflammasome

    Stephanie E Adamczak;Juan Pablo de Rivero Vaccari;Gordon Dale;Frank J Brand

  • Activation of the DNA-binding ability of human heat shock transcription factor 1 may involve the transition from an intramolecular to an intermolecular triple-stranded coiled-coil structure.

    Jianru Zuo;Ruben Baler;Gerhard Dahl;Richard Voellmy

  • Cell Junction and Cyclic AMP: I. Upregulation of Junctional Membrane Permeability and Junctional Membrane Particles by Administration of Cyclic Nucleotide or Phosphodiesterase Inhibitor

    J. L. Flagg-Newton;G. Dahl;W. R. Loewenstein

  • A permeant regulating its permeation pore: inhibition of pannexin 1 channels by ATP

    Feng Qiu;Gerhard Dahl

  • ATP release through pannexon channels.

    Gerhard Dahl

  • Purine Release, Metabolism, and Signaling in the Inflammatory Response.

    Joel Linden;Joel Linden;Friedrich Koch-Nolte;Gerhard Dahl

  • Connexin and pannexin mediated cell-cell communication.

    Eliana Scemes;Sylvia O. Suadicani;Gerhard Dahl;David C. Spray

  • Pannexin 1 Contributes to ATP Release in Airway Epithelia

    George A. Ransford;Nevis Fregien;Feng Qiu;Gerhard Dahl

  • Modulation of membrane channel currents by gap junction protein mimetic peptides: size matters

    Junjie Wang;Meiyun Ma;Silviu Locovei;Robert W. Keane

  • Decoupling of heart muscle cells: Correlation with increased cytoplasmic calcium activity and with changes of nexus ultrastructure

    Gerhard Dahl;Gerrit Isenberg

Frequent Co-Authors

Eliana Scemes
Eliana Scemes New York Medical College
David C. Spray
David C. Spray Albert Einstein College of Medicine
Robert W. Keane
Robert W. Keane University of Miami
Rolf Dermietzel
Rolf Dermietzel Ruhr University Bochum
Kenneth J. Muller
Kenneth J. Muller University of Miami
Richard Voellmy
Richard Voellmy University of Florida
Manfred Gratzl
Manfred Gratzl Ludwig-Maximilians-Universität München
Brian A. MacVicar
Brian A. MacVicar University of British Columbia
Jianru Zuo
Jianru Zuo Chinese Academy of Sciences
W. Dalton Dietrich
W. Dalton Dietrich University of Miami

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