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D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
12643
World Ranking
13136
National Ranking
5601

Overview

Robert W. Keane is affiliated with the University of Miami in the United States. Their research spans multiple disciplines within health sciences, with significant contributions to medicine, biochemistry, genetics, and molecular biology. The scientist's work covers numerous specialized subfields, including molecular biology, neurology, immunology, physiology, and surgery.

Their scholarly output prominently addresses topics related to inflammasomes and immune disorders, heme oxygenase-1 and carbon monoxide, and mechanisms of neuroinflammation and neurodegeneration. Additional areas of focus include Alzheimer's disease research and treatments, extracellular vesicles in disease, traumatic brain injury and neurovascular disturbances, as well as neonatal respiratory health research.

Frequent coauthors in their publications include Juan Pablo de Rivero Vaccari, W. Dalton Dietrich, Helen M. Bramlett, Nadine Kerr, and Roey Hadad. The collaborative nature of their work is reflected in a sustained pattern of partnerships with these researchers.

Robert W. Keane's research has been published in various scientific venues. Prominent journals where their work appears include:

  • International Journal of Molecular Sciences
  • Alzheimer's & Dementia
  • Frontiers in Immunology
  • Translational Research
  • Pharmaceuticals

Recent papers authored or coauthored by Robert W. Keane include:

  • Role of inflammasomes in multiple sclerosis and their potential as therapeutic targets, 2020, Journal of Neuroinflammation
  • The Inflammasome in Times of COVID-19, 2020, Frontiers in Immunology
  • IC100: a novel anti-ASC monoclonal antibody improves functional outcomes in an animal model of multiple sclerosis, 2020, Journal of Neuroinflammation
  • Inflammasome activation in traumatic brain injury and Alzheimer's disease, 2022, Translational Research
  • The Inflammasome Adaptor Protein ASC in Mild Cognitive Impairment and Alzheimer's Disease, 2020, International Journal of Molecular Sciences

Best Publications

  • Apoptosis after traumatic human spinal cord injury

    Evelyne Emery;Philipp Aldana;Mary Bartlett Bunge;William Puckett

  • Traumatic Spinal Cord Injury Induces Nuclear Factor-κB Activation

    John R. Bethea;Marcia Castro;Robert W. Keane;Thomas T. Lee

  • The pannexin 1 channel activates the inflammasome in neurons and astrocytes.

    William R. Silverman;Juan Pablo de Rivero Vaccari;Silviu Locovei;Feng Qiu

  • Cytokines and arachidonic metabolites produced during human immunodeficiency virus (HIV)-infected macrophage-astroglia interactions: implications for the neuropathogenesis of HIV disease.

    Peter Genis;Marti Jett;Edward W. Bernton;Thomas Boyle

  • Pattern recognition receptors and central nervous system repair.

    Kristina A. Kigerl;Juan Pablo de Rivero Vaccari;W. Dalton Dietrich;Phillip G. Popovich

  • Neurones express high levels of a structurally modified, activated form of pp60c-src.

    Joan S. Brugge;Patricia C. Cotton;A. E. Queral;John N. Barrett

  • A Molecular Platform in Neurons Regulates Inflammation after Spinal Cord Injury

    Juan Pablo de Rivero Vaccari;George Lotocki;Alex E. Marcillo;W. Dalton Dietrich

  • Functional Recovery after Peripheral Nerve Injury is Dependent on the Pro-Inflammatory Cytokines IL-1β and TNF: Implications for Neuropathic Pain

    Sylvain Nadeau;Mohammed Filali;Ji Zhang;Bradley J. Kerr

  • Inhibition of the inflammasome complex reduces the inflammatory response after thromboembolic stroke in mice

    Denise P Abulafia;Juan Pablo de Rivero Vaccari;J Diego Lozano;George Lotocki

  • Human astrocytes express a novel NLRP2 inflammasome.

    Julia Minkiewicz;Juan Pablo de Rivero Vaccari;Robert W. Keane

  • Activation and Regulation of Cellular Inflammasomes: Gaps in Our Knowledge for Central Nervous System Injury:

    Juan Pablo de Rivero Vaccari;W Dalton Dietrich;Robert W Keane

  • Therapeutic neutralization of the NLRP1 inflammasome reduces the innate immune response and improves histopathology after traumatic brain injury.

    Juan Pablo de Rivero Vaccari;George Lotocki;Ofelia F Alonso;Helen M Bramlett

  • Pyroptotic neuronal cell death mediated by the AIM2 inflammasome

    Stephanie E Adamczak;Juan Pablo de Rivero Vaccari;Gordon Dale;Frank J Brand

  • Modulation of membrane channel currents by gap junction protein mimetic peptides: size matters

    Junjie Wang;Meiyun Ma;Silviu Locovei;Robert W. Keane

  • Apoptotic and antiapoptotic mechanisms after traumatic brain injury

    Robert W. Keane;Robert W. Keane;Susan Kraydieh;George Lotocki;Ofelia F. Alonso

  • Exosome-mediated inflammasome signaling after central nervous system injury.

    Juan Pablo de Rivero Vaccari;Frank Brand;Stephanie Adamczak;Stephanie W. Lee

  • Apoptotic and Anti-Apoptotic Mechanisms Following Spinal Cord Injury

    Robert W. Keane;Robert W. Keane;Susan Kraydieh;George Lotocki;John R. Bethea

  • ACTIVATION OF CPP32 DURING APOPTOSIS OF NEURONS AND ASTROCYTES

    Robert W. Keane;Robert W. Keane;Anu Srinivasan;Lyndon M. Foster;Maria Pia Testa

  • P2X4 Receptors Influence Inflammasome Activation after Spinal Cord Injury

    Juan Pablo de Rivero Vaccari;Dominic Bastien;Geoffrey Yurcisin;Isabelle Pineau

  • Inflammasome proteins in cerebrospinal fluid of brain-injured patients as biomarkers of functional outcome: clinical article.

    Stephanie Adamczak;Gordon Dale;Juan Pablo de Rivero Vaccari;M. Ross Bullock

Frequent Co-Authors

W. Dalton Dietrich
W. Dalton Dietrich University of Miami
Gerhard Dahl
Gerhard Dahl University of Miami
John R. Bethea
John R. Bethea George Washington University
Deborah C. Mash
Deborah C. Mash University of Miami
Eliana Scemes
Eliana Scemes New York Medical College
John C. Reed
John C. Reed Johnson & Johnson (United States)
Donald W. Nicholson
Donald W. Nicholson MSD (United States)
Scott R. Whittemore
Scott R. Whittemore University of Louisville
Dale E. Bredesen
Dale E. Bredesen University of California, Los Angeles
Joan S. Brugge
Joan S. Brugge Harvard University

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