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Biology and Biochemistry

D-Index
51
Citations
10272
World Ranking
17103
National Ranking
7049

Overview

John R. Bethea is affiliated with George Washington University in the United States. Their research primarily intersects the fields of medicine and neuroscience, focusing on pathologies related to spinal cord injury, pain mechanisms, and neuroimmune interactions.

The main fields of study for their work include:

  • Medicine
  • Neuroscience

Within these fields, their subfields of study cover:

  • Pathology and Forensic Medicine
  • Neurology
  • Physiology
  • Cellular and Molecular Neuroscience
  • Endocrine and Autonomic Systems

Their research spans several specialized topics, including:

  • Spinal Cord Injury Research
  • Pain Mechanisms and Treatments
  • Neuroscience of respiration and sleep
  • Multiple Sclerosis Research Studies
  • Neuropeptides and Animal Physiology
  • Peripheral Neuropathies and Disorders
  • Endoplasmic Reticulum Stress and Disease

Among the recent papers featuring their work are:

  • Role of Peripheral Immune Cells for Development and Recovery of Chronic Pain, 2021, Frontiers in Immunology
  • Inflammation and Oxidative Stress in Multiple Sclerosis: Consequences for Therapy Development, 2020, Oxidative Medicine and Cellular Longevity
  • Aorta in Pathologies May Function as an Immune Organ by Upregulating Secretomes for Immune and Vascular Cell Activation, Differentiation and Trans-Differentiation-Early Secretomes may Serve as Drivers for Trained Immunity, 2022, Frontiers in Immunology
  • TNFα in MS and Its Animal Models: Implications for Chronic Pain in the Disease, 2021, Frontiers in Neurology
  • Pharmacological Inhibition of Soluble Tumor Necrosis Factor-Alpha Two Weeks after High Thoracic Spinal Cord Injury Does Not Affect Sympathetic Hyperreflexia, 2021, Journal of Neurotrauma

John R. Bethea frequently collaborates with several researchers, including:

  • J. Ricard
  • Kayla L. Nguyen
  • Shruti Gupta
  • Sreejita Arnab
  • David Mendelowitz

Common venues where their work has been published include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology
  • Brain Research Bulletin
  • Oxidative Medicine and Cellular Longevity
  • Frontiers in Neurology

Best Publications

  • Inhibition of astroglial nuclear factor κB reduces inflammation and improves functional recovery after spinal cord injury

    Roberta Brambilla;Valerie Bracchi-Ricard;Wen Hui Hu;Beata Frydel

  • Apoptosis after traumatic human spinal cord injury

    Evelyne Emery;Philipp Aldana;Mary Bartlett Bunge;William Puckett

  • Traumatic Spinal Cord Injury Induces Nuclear Factor-κB Activation

    John R. Bethea;Marcia Castro;Robert W. Keane;Thomas T. Lee

  • Systemically administered interleukin-10 reduces tumor necrosis factor-alpha production and significantly improves functional recovery following traumatic spinal cord injury in rats.

    John R. Bethea;Hideki Nagashima;Marcia C. Acosta;Carmen Briceno

  • Transgenic inhibition of astroglial NF-kappa B improves functional outcome in experimental autoimmune encephalomyelitis by suppressing chronic central nervous system inflammation.

    Roberta Brambilla;Trikaldarshi Persaud;Xianchen Hu;Shaffiat Karmally

  • Targeting the host inflammatory response in traumatic spinal cord injury.

    John R Bethea;W Dalton Dietrich

  • Photochemically induced cerebral infarction. I. Early microvascular alterations.

    W. D. Dietrich;B. D. Watson;R. Busto;M. D. Ginsberg

  • Effects of interleukin-10 (IL-10) on pain behavior and gene expression following excitotoxic spinal cord injury in the rat.

    Jeffery A. Plunkett;Chen Guang Yu;Julia M. Easton;John R. Bethea

  • Cytokine involvement in dynorphin-induced allodynia.

    Tinna M. Laughlin;John R. Bethea;Robert P. Yezierski;George L. Wilcox

  • Inhibition of soluble tumour necrosis factor is therapeutic in experimental autoimmune encephalomyelitis and promotes axon preservation and remyelination.

    Roberta Brambilla;Jessica Jopek Ashbaugh;Jessica Jopek Ashbaugh;Roberta Magliozzi;Anna Dellarole

  • Neuroprotective effects of interleukin-10 following excitotoxic spinal cord injury.

    Kori L. Brewer;John R. Bethea;Robert P. Yezierski

  • Apoptotic and Anti-Apoptotic Mechanisms Following Spinal Cord Injury

    Robert W. Keane;Robert W. Keane;Susan Kraydieh;George Lotocki;John R. Bethea

  • Transgenic inhibition of glial NF-kappa B reduces pain behavior and inflammation after peripheral nerve injury.

    Eugene S. Fu;Yan Ping Zhang;Jacqueline Sagen;Keith A. Candiotti

  • Astrocytes play a key role in EAE pathophysiology by orchestrating in the CNS the inflammatory response of resident and peripheral immune cells and by suppressing remyelination

    Roberta Brambilla;Roberta Brambilla;Paul D. Morton;Paul D. Morton;Jessica Jopek Ashbaugh;Jessica Jopek Ashbaugh;Shaffiat Karmally

  • Spinal cord injury-induced inflammation: a dual-edged sword.

    John R. Bethea

  • NIBP, a Novel NIK and IKKβ-binding Protein That Enhances NF-κB Activation

    Wen Hui Hu;Wen Hui Hu;Julie S. Pendergast;Julie S. Pendergast;Xian Ming Mo;Roberta Brambilla

  • Inactivation of astroglial NF-κB promotes survival of retinal neurons following ischemic injury

    Galina Dvoriantchikova;David Barakat;Roberta Brambilla;Christian Agudelo

  • Tumor necrosis factor-α enhances interferon-γ-mediated class II antigen expression on astrocytes

    Etty N. Benveniste;Shaun M. Sparacio;John R. Bethea

  • Neuropathic pain-induced depressive-like behavior and hippocampal neurogenesis and plasticity are dependent on TNFR1 signaling.

    Anna Dellarole;Paul Morton;Roberta Brambilla;Winston Walters

  • Regulation of Nogo and Nogo receptor during the development of the entorhino-hippocampal pathway and after adult hippocampal lesions.

    Ana Mingorance;Xavier Fontana;Marta Solé;Ferran Burgaya

Frequent Co-Authors

Roman Fischer
Roman Fischer University of Oxford
Karen A. Moxon
Karen A. Moxon University of California, Davis
W. Dalton Dietrich
W. Dalton Dietrich University of Miami
Robert W. Keane
Robert W. Keane University of Miami
Michael D. Norenberg
Michael D. Norenberg University of Miami
Damien D. Pearse
Damien D. Pearse University of Miami
Roland E. Kontermann
Roland E. Kontermann University of Stuttgart
Klaus Pfizenmaier
Klaus Pfizenmaier University of Stuttgart
Jacqueline Sagen
Jacqueline Sagen University of Miami
Robert P. Yezierski
Robert P. Yezierski University of Florida

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