D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 78 Citations 21,418 189 World Ranking 2844 National Ranking 204

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Apoptosis

His primary areas of study are Tumor necrosis factor alpha, Cell biology, Receptor, Immunology and Cancer research. The study incorporates disciplines such as Apoptosis, Immune system and B-cell activating factor in addition to Tumor necrosis factor alpha. Klaus Pfizenmaier has included themes like Ceramide and Biochemistry in his Cell biology study.

His Receptor study combines topics in areas such as Cytokine and Fusion protein. His Immunology study which covers Cytotoxic T cell that intersects with In vivo, Antigen, Interleukin 2 and Molecular biology. His research integrates issues of Cell culture and Cytotoxicity in his study of Cancer research.

His most cited work include:

  • Tumor necrosis factor signaling. (1836 citations)
  • THE TRANSMEMBRANE FORM OF TUMOR NECROSIS FACTOR IS THE PRIME ACTIVATING LIGAND OF THE 80 KDA TUMOR NECROSIS FACTOR RECEPTOR (1112 citations)
  • Neurodegenerative and neuroprotective effects of tumor Necrosis factor (TNF) in retinal ischemia: opposite roles of TNF receptor 1 and TNF receptor 2. (493 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Tumor necrosis factor alpha, Cell biology, Molecular biology, Cancer research and Immunology. His studies deal with areas such as Cytokine, Receptor, Biochemistry, Fusion protein and Programmed cell death as well as Tumor necrosis factor alpha. His work deals with themes such as Inflammation and Endocrinology, which intersect with Receptor.

His Molecular biology study deals with Cell culture intersecting with Gene expression. His studies in Cancer research integrate themes in fields like Cancer cell, Cancer, Apoptosis, Prodrug and Matrix metalloproteinase. His Immunology research includes themes of Cytotoxic T cell and In vivo.

He most often published in these fields:

  • Tumor necrosis factor alpha (33.33%)
  • Cell biology (30.65%)
  • Molecular biology (28.49%)

What were the highlights of his more recent work (between 2015-2020)?

  • Tumor necrosis factor alpha (33.33%)
  • Cancer research (23.66%)
  • Fusion protein (16.13%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Tumor necrosis factor alpha, Cancer research, Fusion protein, Antibody and Inflammation. His Tumor necrosis factor alpha study is concerned with Immunology in general. The Cancer research study combines topics in areas such as Stroma, Monoclonal, Cancer cell, Apoptosis and Anti pd 1.

The concepts of his Fusion protein study are interwoven with issues in In vitro, Ligand, Stereochemistry, Cell biology and Mutagenesis. His Antibody research integrates issues from Tumor microenvironment, Tumor necrosis factor receptor 1, Tnf receptor 1 and Antigen. His work carried out in the field of Inflammation brings together such families of science as Psoriasis, Pathology, Receptor, Dialysis and Pharmacology.

Between 2015 and 2020, his most popular works were:

  • Essential protective role of tumor necrosis factor receptor 2 in neurodegeneration (69 citations)
  • An optimized antibody-single-chain TRAIL fusion protein for cancer therapy. (23 citations)
  • Preclinical Efficacy of Endoglin-Targeting Antibody-Drug Conjugates for the Treatment of Ewing Sarcoma. (18 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Immune system

The scientist’s investigation covers issues in Tumor necrosis factor alpha, Immunology, Tumor necrosis factor receptor 2, Inflammation and Central nervous system. His Immunology study integrates concerns from other disciplines, such as In vivo and Cell biology. His work deals with themes such as Signal transduction, Homology and Transmembrane protein, which intersect with In vivo.

In his research, Fusion protein and Ligand is intimately related to In vitro, which falls under the overarching field of Cell biology. His research in Inflammation intersects with topics in Therapeutic effect, Neuropathic pain, Pharmacology and Agonist, Receptor. The Central nervous system study combines topics in areas such as Neurodegeneration, Programmed cell death and Neuroprotection.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Tumor necrosis factor signaling.

H Wajant;K Pfizenmaier;P Scheurich.
Cell Death & Differentiation (2003)

2736 Citations

THE TRANSMEMBRANE FORM OF TUMOR NECROSIS FACTOR IS THE PRIME ACTIVATING LIGAND OF THE 80 KDA TUMOR NECROSIS FACTOR RECEPTOR

Matthias Grell;Eleni Douni;Harald Wajant;Matthias Löhden.
Cell (1995)

1654 Citations

PKCu is a novel, atypical member of the protein kinase C family.

F.J. Johannes;J. Prestle;S. Eis;P. Oberhagemann.
Journal of Biological Chemistry (1994)

731 Citations

PKC zeta is a molecular switch in signal transduction of TNF‐alpha, bifunctionally regulated by ceramide and arachidonic acid.

Gertraud Müller;Mohamed Ayoub;Peter Storz;Jörg Rennecke.
The EMBO Journal (1995)

701 Citations

Immunoregulatory activity of recombinant human tumor necrosis factor (TNF)-alpha: induction of TNF receptors on human T cells and TNF-alpha-mediated enhancement of T cell responses

P Scheurich;B Thoma;U Ucer;K Pfizenmaier.
Journal of Immunology (1987)

660 Citations

Tumor necrosis factor (TNF)-mediated neuroprotection against glutamate-induced excitotoxicity is enhanced by N-methyl-D-aspartate receptor activation. Essential role of a TNF receptor 2-mediated phosphatidylinositol 3-kinase-dependent NF-kappa B pathway.

Lara Marchetti;Matthias Klein;Katalin Schlett;Katalin Schlett;Klaus Pfizenmaier.
Journal of Biological Chemistry (2004)

537 Citations

Neurodegenerative and neuroprotective effects of tumor Necrosis factor (TNF) in retinal ischemia: opposite roles of TNF receptor 1 and TNF receptor 2.

Valerie Fontaine;Saddek Mohand-Said;Noelle Hanoteau;Céline Fuchs.
The Journal of Neuroscience (2002)

521 Citations

Cyclophosphamide-sensitive T lymphocytes suppress the in vivo generation of antigen-specific cytotoxic T lymphocytes

M Rollinghoff;A Starzinski-Powitz;K Pfizenmaier;H Wagner.
Journal of Experimental Medicine (1977)

447 Citations

Protein kinase D regulates vesicular transport by phosphorylating and activating phosphatidylinositol-4 kinase IIIβ at the Golgi complex

Angelika Hausser;Peter Storz;Susanne Märtens;Gisela Link.
Nature Cell Biology (2005)

426 Citations

Tumor necrosis factor enhances HLA-A,B,C and HLA-DR gene expression in human tumor cells.

K Pfizenmaier;P Scheurich;C Schlüter;M Krönke.
Journal of Immunology (1987)

328 Citations

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