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Christian Klein

D-Index & Metrics

Biology and Biochemistry

D-Index
76
Citations
29336
World Ranking
4947
National Ranking
92

Christian Klein publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Christian Klein sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 446 publications — 93rd percentile

93% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Christian Klein D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Christian Klein sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 76 D-Index — 75th percentile

75% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Christian Klein is affiliated with Roche (Switzerland) in Switzerland and contributes extensively to the field of medicine, with a significant focus on oncology and immunology. Their published work encompasses several high-impact research topics and venues, reflecting a diverse research portfolio.

Their main fields of study include:

  • Medicine

Within this broad field, subfields of study cover:

  • Oncology
  • Immunology
  • Radiology, Nuclear Medicine and Imaging
  • Molecular Biology
  • Pathology and Forensic Medicine

Christian Klein's research interests revolve around key topics such as:

  • CAR-T cell therapy research
  • Monoclonal and Polyclonal Antibodies Research
  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • Immune Cell Function and Interaction
  • Lymphoma Diagnosis and Treatment
  • Chronic Lymphocytic Leukemia Research

Their recent publications illustrate active engagement in cutting-edge immunotherapy and molecular biology research. Notable papers include:

  • "The present and future of bispecific antibodies for cancer therapy," 2024, published in Nature Reviews Drug Discovery
  • "Ångström-resolution fluorescence microscopy," 2023, published in Nature
  • "PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program," 2022, published in Nature
  • "PD-1-cis IL-2R agonism yields better effectors from stem-like CD8+ T cells," 2022, published in Nature
  • "Dendritic cells dictate responses to PD-L1 blockade cancer immunotherapy," 2020, published in Science Translational Medicine

Christian Klein frequently collaborates with the following coauthors:

  • Pablo Umaña
  • Marina Bacac
  • Johannes Sam
  • Sara Colombetti
  • Laura Codarri Deak

Their work is often published in journals specialized in cancer and immunotherapy research, including:

  • Cancer Research
  • Blood
  • mAbs
  • Journal for ImmunoTherapy of Cancer
  • Nature Communications

In addition to journal publications, Christian Klein has contributed to book publications with the following publishers and titles:

  • Vandenhoeck & Ruprecht: "Gespräche auf den Punkt" (2022, 2023)
  • J.B. Metzler: "Werner Kofler intermedial" (2021)

Best Publications

  • In vivo activation of the p53 pathway by small-molecule antagonists of MDM2.

    Lyubomir T. Vassilev;Binh T. Vu;Bradford Graves;Daisy Carvajal

  • Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell–mediated B-cell cytotoxicity

    Ekkehard Mössner;Peter Brünker;Samuel Moser;Ursula Püntener

  • A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade

    Daniela S. Thommen;Daniela S. Thommen;Viktor H. Koelzer;Petra Herzig;Andreas Roller

  • Target Binding Properties and Cellular Activity of Afatinib (BIBW 2992), an Irreversible ErbB Family Blocker.

    Flavio Solca;Goeran Dahl;Andreas Zoephel;Gerd Bader

  • Climate change impact and adaptation for wheat protein

    Senthold Asseng;Pierre Martre;Andrea Maiorano;Reimund P Rötter

  • Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies

    Wolfgang Schaefer;Jörg T. Regula;Monika Bähner;Jürgen Schanzer

  • Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling

    Moritz Felcht;Robert Luck;Alexander Schering;Philipp Seidel

  • Epitope interactions of monoclonal antibodies targeting CD20 and their relationship to functional properties

    Christian Klein;Alfred Lammens;Wolfgang Schäfer;Guy Georges

  • Novel human IgG1 and IgG4 Fc-engineered antibodies with completely abolished immune effector functions

    Tilman Schlothauer;Sylvia Herter;Claudia Ferrara Koller;Sandra Grau-Richards

  • Preclinical Activity of the Type II CD20 Antibody GA101 (Obinutuzumab) Compared with Rituximab and Ofatumumab In Vitro and in Xenograft Models

    Sylvia Herter;Frank Herting;Olaf Mundigl;Inja Waldhauer

  • Progression of Lung Cancer Is Associated with Increased Dysfunction of T Cells Defined by Coexpression of Multiple Inhibitory Receptors

    Daniela Stefanie Thommen;Jens Schreiner;Philipp Müller;Petra Herzig

  • A Novel Carcinoembryonic Antigen T-Cell Bispecific Antibody (CEA TCB) for the Treatment of Solid Tumors.

    Marina Bacac;Tanja Fauti;Johannes Sam;Sara Colombetti

  • Dendritic cells dictate responses to PD-L1 blockade cancer immunotherapy.

    Maud Mayoux;Andreas Roller;Vesna Pulko;Stefano Sammicheli

  • Chalcone derivatives antagonize interactions between the human oncoprotein MDM2 and p53.

    Raphael Stoll;Christian Renner;Silke Hansen;Stefan Palme

  • Bivalent, bispecific antibodies

    Christian Klein;Wolfgang Schaefer

  • p53 contains large unstructured regions in its native state.

    Stefan Bell;Christian Klein;Lin Müller;Silke Hansen

  • Cergutuzumab amunaleukin (CEA-IL2v), a CEA-targeted IL-2 variant-based immunocytokine for combination cancer immunotherapy: Overcoming limitations of aldesleukin and conventional IL-2-based immunocytokines.

    Christian Klein;Inja Waldhauer;Valeria G. Nicolini;Anne Freimoser-Grundschober

  • Target Expression, Generation, Preclinical Activity, and Pharmacokinetics of the BCMA-T Cell Bispecific Antibody EM801 for Multiple Myeloma Treatment

    Anja Seckinger;Jose Antonio Delgado;Samuel Moser;Laura Moreno

  • WT p53, but not tumor-derived mutants, bind to Bcl2 via the DNA binding domain and induce mitochondrial permeabilization.

    York Tomita;Natasha Marchenko;Susan Erster;Alice Nemajerova

  • Progress in overcoming the chain association issue in bispecific heterodimeric IgG antibodies

    Christian Klein;Claudio Sustmann;Markus Thomas;Kay Stubenrauch

Frequent Co-Authors

Sebastian Kobold
Sebastian Kobold Ludwig-Maximilians-Universität München
Stefan Endres
Stefan Endres Ludwig-Maximilians-Universität München
Ulrich Brinkmann
Ulrich Brinkmann Roche (Switzerland)
Jean-Jacques Fournié
Jean-Jacques Fournié Cancer Research Center of Toulouse
Horst Kessler
Horst Kessler Technical University of Munich
Mitchell S. Cairo
Mitchell S. Cairo New York Medical College
Otto C. Boerman
Otto C. Boerman Radboud University
Marije I. Koenders
Marije I. Koenders Radboud University
Karl-Peter Hopfner
Karl-Peter Hopfner Ludwig-Maximilians-Universität München
Eckart Priesack
Eckart Priesack University of Bonn

External Links

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Best Scientists Citing Christian Klein

David P. Lane

David P. Lane

Karolinska Institute

Publications: 77

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Chandra S. Verma

Agency for Science, Technology and Research

Publications: 71

Benjamin Doerr

Benjamin Doerr

École Polytechnique

Publications: 54

Michael Hallek

Michael Hallek

University of Cologne

Publications: 42

Alexander Dömling

Alexander Dömling

Palacký University, Olomouc

Publications: 40

Vladimir N. Uversky

Vladimir N. Uversky

University of South Florida

Publications: 38

Mark S. Cragg

Mark S. Cragg

University of Southampton

Publications: 36

Dario Neri

Dario Neri

Philogen (Italy)

Publications: 35

Ted R. Hupp

Ted R. Hupp

University of Edinburgh

Publications: 34

Paul W. H. I. Parren

Paul W. H. I. Parren

Leiden University Medical Center

Publications: 30

Hellmut G. Augustin

Hellmut G. Augustin

Heidelberg University

Publications: 30

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Tad A. Holak

Jagiellonian University

Publications: 27

Craig M. Crews

Craig M. Crews

Yale University

Publications: 27

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Jean-Christophe Marine

KU Leuven

Publications: 25

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Karen H. Vousden

The Francis Crick Institute

Publications: 24

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Galina Selivanova

Karolinska Institute

Publications: 24

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