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Immunology

D-Index
71
Citations
15562
World Ranking
2349
National Ranking
93

Overview

Jean-Jacques Fournié is affiliated with the Federal University of Toulouse Midi-Pyrénées in France and has contributed extensively to research in immunology, microbiology, molecular biology, and medicine. Their work spans a range of interconnected scientific fields and topics, focusing on immune cell function, cancer immunotherapy, and molecular mechanisms underlying disease processes.

The primary fields of study reflected in Fournié's publications include:

  • Immunology and Microbiology
  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broad fields, Fournié has engaged deeply with several subfields, including:

  • Immunology
  • Molecular Biology
  • Oncology
  • Cancer Research
  • Pathology and Forensic Medicine

The scientist's research addresses multiple key topics such as:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Single-cell and Spatial Transcriptomics
  • Cancer Immunotherapy and Biomarkers
  • CAR-T Cell Therapy Research
  • Epigenetics and DNA Methylation
  • Lymphoma Diagnosis and Treatment

Among Fournié's recent publications are:

  • PD-1 blockade restores helper activity of tumor-infiltrating, exhausted PD-1hiCD39+ CD4 T cells, 2020, JCI Insight
  • Mitochondrial inhibitors circumvent adaptive resistance to venetoclax and cytarabine combination therapy in acute myeloid leukemia, 2021, Nature Cancer
  • Cancer cell adaptability: turning ribonucleoprotein granules into targets, 2021, Trends in Cancer
  • Dual Relief of T-lymphocyte Proliferation and Effector Function Underlies Response to PD-1 Blockade in Epithelial Malignancies, 2020, Cancer Immunology Research
  • Global DNA hypermethylation pattern and unique gene expression signature in liver cancer from patients with Indigenous American ancestry, 2021, Oncotarget

Frequent collaborators in their research include Camille Laurent, Marie Tosolini, Frédéric Pont, Juan-Pablo Cerapio, and Loïc Ysebaert. Collaborations with these researchers indicate a network of partnerships mainly in immunology and cancer research.

Jean-Jacques Fournié's works have appeared primarily in publication venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancers
  • Cancer Immunology Research
  • Cell Reports
  • Immunological Reviews

This body of work reflects a focus on understanding immune responses, particularly involving T cells, and investigating mechanisms of cancer resistance and adaptability. Topics such as PD-1 blockade and epigenetic modifications feature prominently, aligned with ongoing developments in immunotherapy and targeted cancer treatment.

Best Publications

  • Stimulation of human gamma delta T cells by nonpeptidic mycobacterial ligands

    Patricia Constant;François Davodeau;Marie-Alix Peyrat;Yannick Poquet

  • Human Solid Tumors Contain High Endothelial Venules: Association with T- and B-Lymphocyte Infiltration and Favorable Prognosis in Breast Cancer

    Ludovic Martinet;Ignacio Garrido;Thomas Filleron;Sophie Le Guellec

  • Differentiation, phenotype, and function of interleukin-17-producing human Vγ9Vδ2 T cells.

    Nadia Caccamo;Carmela La Mendola;Valentina Orlando;Serena Meraviglia

  • Granulysin-Dependent Killing of Intracellular and Extracellular Mycobacterium tuberculosis by Vγ9/Vδ2 T Lymphocytes

    Francesco Dieli;Marita Troye-Blomberg;Juraj Ivanyi;Jean Jacques Fournié

  • Structure of a human gammadelta T-cell antigen receptor.

    Timothy J. Allison;Christine C. Winter;Jean-Jacques Fournié;Marc Bonneville

  • Murine natural killer cells contribute to the granulomatous reaction caused by mycobacterial cell walls

    I. Apostolou;Y. Takahama;C. Belmant;T. Kawano

  • A Phosphorus-Based Dendrimer Targets Inflammation and Osteoclastogenesis in Experimental Arthritis

    Myriam Hayder;Mary Poupot;Michel Baron;Michel Baron;Michel Baron;Delphine Nigon

  • In Vivo Immunomanipulation of Vγ9Vδ2 T Cells with a Synthetic Phosphoantigen in a Preclinical Nonhuman Primate Model

    Hélène Sicard;Sophie Ingoure;Béatrice Luciani;Claire Serraz

  • Early activation of human V gamma 9V delta 2 T cell broad cytotoxicity and TNF production by nonpeptidic mycobacterial ligands.

    F Lang;M A Peyrat;P Constant;F Davodeau

  • Single-cell RNA sequencing unveils the shared and the distinct cytotoxic hallmarks of human TCRVδ1 and TCRVδ2 γδ T lymphocytes.

    Gabriele Pizzolato;Hannah Kaminski;Marie Tosolini;Don-Marc Franchini

  • Human γδ T Cells Induce Dendritic Cell Maturation

    Jamila Ismaili;Jamila Ismaili;Véronique Olislagers;Véronique Olislagers;Rémy Poupot;Rémy Poupot;Jean-Jacques Fournié;Jean-Jacques Fournié

  • Recent Advances in Microwave-Based Dielectric Spectroscopy at the Cellular Level for Cancer Investigations

    Katia Grenier;David Dubuc;Tong Chen;Francois Artis

  • FcγRIII discriminates between 2 subsets of Vγ9Vδ2 effector cells with different responses and activation pathways

    Daniela F. Angelini;Giovanna Borsellino;Mary Poupot;Adamo Diamantini

  • Chemical synthesis and biological activity of bromohydrin pyrophosphate, a potent stimulator of human gamma delta T cells.

    Eric Espinosa;Christian Belmant;Fréderic Pont;Béatrice Luciani

  • CXCR5 Identifies a Subset of Vγ9Vδ2 T Cells which Secrete IL-4 and IL-10 and Help B Cells for Antibody Production

    Nadia Caccamo;Luca Battistini;Marc Bonneville;Fabrizio Poccia

  • CD94/NKG2 inhibitory receptor complex modulates both anti-viral and anti-tumoral responses of polyclonal phosphoantigen-reactive V gamma 9V delta 2 T lymphocytes.

    Fabrizio Poccia;Barbara Cipriani;Silvia Vendetti;Vittorio Colizzi

  • What lessons can be learned from γδ T cell-based cancer immunotherapy trials?

    Jean Jacques Fournié;Hélène Sicard;Mary Poupot;Mary Poupot;Mary Poupot;Christine Bezombes;Christine Bezombes;Christine Bezombes

  • Control of self-reactive cytotoxic T lymphocytes expressing γδ T cell receptors by natural killer inhibitory receptors

    Franck Halary;Marie Alix Peyrat;Eric Champagne;Miguel Lopez-Botet

  • Vγ9/Vδ2 T lymphocytes reduce the viability of intracellular Mycobacterium tuberculosis

    Francesco Dieli;Marita Troye-Blomberg;Juraj Ivanyi;Jean Jacques Fournié

  • Bromohydrin pyrophosphate enhances antibody-dependent cell-mediated cytotoxicity induced by therapeutic antibodies.

    Julie Gertner-Dardenne;Julie Gertner-Dardenne;Cecile Bonnafous;Christine Bezombes;Christine Bezombes;Aude-Hélène Capietto;Aude-Hélène Capietto

  • Peripheral V gamma 9/V delta 2 T cell deletion and anergy to nonpeptidic mycobacterial antigens in asymptomatic HIV-1-infected persons.

    F Poccia;S Boullier;H Lecoeur;M Cochet

  • V gamma 9V delta 2 T lymphocytes efficiently recognize and kill zoledronate-sensitized, imatinib-sensitive, and imatinib-resistant chronic myelogenous leukemia cells.

    Matilde D’Asaro;Carmela La Mendola;Diana Di Liberto;Valentina Orlando

Frequent Co-Authors

Marc Bonneville
Marc Bonneville Institut Mérieux (France)
Germain Puzo
Germain Puzo Federal University of Toulouse Midi-Pyrénées
Francesco Dieli
Francesco Dieli University of Palermo
Anne-Marie Caminade
Anne-Marie Caminade Centre national de la recherche scientifique, CNRS
Christian Klein
Christian Klein Roche (Switzerland)
Marie-Lise Gougeon
Marie-Lise Gougeon Institut Pasteur
Luca Battistini
Luca Battistini Albert Einstein College of Medicine
Jean-Pierre Majoral
Jean-Pierre Majoral Centre national de la recherche scientifique, CNRS
Massimo Massaia
Massimo Massaia University of Turin
Els Verhoeyen
Els Verhoeyen Inserm : Institut national de la santé et de la recherche médicale

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