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Bruno Silva-Santos

Bruno Silva-Santos

D-Index & Metrics

Immunology

D-Index
58
Citations
13235
World Ranking
3505
National Ranking
4

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Bruno Silva-Santos is affiliated with the University of Lisbon in Portugal. Their research primarily focuses on immunology, with extensive contributions in related fields including medicine, oncology, molecular biology, infectious diseases, and physiology.

The scientist's work spans several topics within immunology, notably:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • CAR-T cell therapy research
  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • IL-33, ST2, and ILC Pathways
  • Cancer Cells and Metastasis

Bruno Silva-Santos's recent publications include:

  • "γδ T cells in tissue physiology and surveillance," 2020, Nature Reviews Immunology
  • "The emerging roles of γδ T cells in cancer immunotherapy," 2023, Nature Reviews Clinical Oncology
  • "Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade," 2020, Immunity
  • "Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments," 2021, Nature Immunology
  • "IL-17 triggers the onset of cognitive and synaptic deficits in early stages of Alzheimer's disease," 2021, Cell Reports

The frequent coauthors collaborating with Silva-Santos include:

  • Sofia Mensurado
  • Julie C. Ribot
  • Anita Quintal Gomes
  • Gina J. Fiala
  • Pedro H. Papotto

Their work is often published in prominent journals, with notable frequent publication venues being:

  • Nature Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The biomedical & life sciences collection
  • Immunity
  • Cell Reports

Silva-Santos's contributions to immunology and microbiology are documented through a significant number of publications, comprising 73 papers in immunology and 51 in medicine.

Their research has been recognized with membership in the European Molecular Biology Organization (EMBO).

Best Publications

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Andreas Acs

  • CD27 is a thymic determinant of the balance between interferon-gamma- and interleukin 17-producing gammadelta T cell subsets.

    Julie C Ribot;Ana deBarros;Ana deBarros;Dick John Pang;Joana F Neves;Joana F Neves

  • γδ T cells in cancer.

    Bruno Silva-Santos;Karine Serre;Håkan Norell

  • Classification of current anticancer immunotherapies

    Lorenzo Galluzzi;Erika Vacchelli;José Manuel Bravo-San Pedro;Aitziber Buqué

  • γδ T cells in tissue physiology and surveillance.

    Julie C. Ribot;Noëlla Lopes;Bruno Silva-Santos

  • γδ T cells: pleiotropic immune effectors with therapeutic potential in cancer

    Bruno Silva-Santos;Sofia Mensurado;Seth B. Coffelt

  • Translating gammadelta (γδ) T cells and their receptors into cancer cell therapies

    Zsolt Sebestyen;Immo Prinz;Julie Déchanet-Merville;Bruno Silva-Santos

  • IL-17+ γδ T cells as kick-starters of inflammation.

    Pedro H Papotto;Julie C Ribot;Bruno Silva-Santos

  • The emerging roles of γδ T cells in cancer immunotherapy

    Unknown

  • Meningeal γδ T cell–derived IL-17 controls synaptic plasticity and short-term memory

    Miguel Ribeiro;Helena C. Brigas;Mariana Temido-Ferreira;Paula A. Pousinha

  • Differentiation of human peripheral blood Vδ1+ T cells expressing the natural cytotoxicity receptor NKp30 for recognition of lymphoid leukemia cells

    Daniel V. Correia;Daniel V. Correia;Manuela Fogli;Kelly Hudspeth;Maria Gomes da Silva

  • Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade.

    Eduardo Bonavita;Christian P. Bromley;Gustav Jonsson;Victoria S. Pelly

  • Functional development of γδ T cells.

    Immo Prinz;Bruno Silva-Santos;Daniel J. Pennington

  • Murine CD27(-) Vγ6(+) γδ T cells producing IL-17A promote ovarian cancer growth via mobilization of protumor small peritoneal macrophages.

    Margarida Rei;Natacha Gonçalves-Sousa;Telma Lança;Richard G. Thompson

  • Delta One T Cells for Immunotherapy of Chronic Lymphocytic Leukemia: Clinical-Grade Expansion/Differentiation and Preclinical Proof of Concept

    Afonso Rm Almeida;Daniel V Correia;Ana Fernandes-Platzgummer;Cláudia L da Silva

  • Lymphotoxin-Mediated Regulation of γδ Cell Differentiation by αß T Cell Progenitors

    Bruno Silva-Santos;Daniel J. Pennington;Adrian C. Hayday

  • Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27–CD70 pathway

    Jonathan M. Coquet;Julie C. Ribot;Nikolina Bąbała;Sabine Middendorp

  • IL-17 triggers the onset of cognitive and synaptic deficits in early stages of Alzheimer’s disease

    Helena C. Brigas;Miguel Ribeiro;Joana E. Coelho;Rui Gomes;Rui Gomes

  • Protective Role of the Inflammatory CCR2/CCL2 Chemokine Pathway through Recruitment of Type 1 Cytotoxic γδ T Lymphocytes to Tumor Beds

    Telma Lança;Maria Fernanda Costa;Natacha Gonçalves-Sousa;Margarida Rei

  • Natural cytotoxicity receptors: broader expression patterns and functions in innate and adaptive immune cells.

    Kelly Hudspeth;Bruno Silva-Santos;Domenico Mavilio

  • The MHC class Ib protein ULBP1 is a nonredundant determinant of leukemia/lymphoma susceptibility to γδ T-cell cytotoxicity

    Telma Lança;Daniel V. Correia;Daniel V. Correia;Catarina F. Moita;Helena Raquel

  • Targeting γδ T lymphocytes for cancer immunotherapy: from novel mechanistic insight to clinical application.

    Anita Q. Gomes;Duarte S. Martins;Bruno Silva-Santos

  • promote ovarian cancer growth via mobilization of protumor small peritoneal macrophages

    Margarida Rei;Natacha Gonçalves-Sousa;Telma Lança;Richard G. Thompson

Frequent Co-Authors

Adrian Hayday
Adrian Hayday King's College London
Immo Prinz
Immo Prinz Hannover Medical School
Domenico Mavilio
Domenico Mavilio University of Milan
Ari Waisman
Ari Waisman Johannes Gutenberg University of Mainz
Lorenzo Moretta
Lorenzo Moretta Bambino Gesù Children's Hospital
Roland S. Liblau
Roland S. Liblau Federal University of Toulouse Midi-Pyrénées
Jannie Borst
Jannie Borst Leiden University Medical Center
Luísa V. Lopes
Luísa V. Lopes University of Lisbon
Maria M. Mota
Maria M. Mota University of Lisbon
Daniel E. Speiser
Daniel E. Speiser University of Lausanne

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