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Daniela Wesch

Daniela Wesch

D-Index & Metrics

Immunology

D-Index
50
Citations
7471
World Ranking
4274
National Ranking
284

Overview

Daniela Wesch is affiliated with Kiel University in Germany and has contributed extensively to the fields of immunology and medicine. Their research spans multiple subfields including immunology, oncology, molecular biology, genetics, and radiology with a particular focus on immune cell function and interaction.

The scientist's main research areas include:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • CAR-T cell therapy research
  • Immunotherapy and Immune Responses
  • Pancreatic and Hepatic Oncology Research
  • Cancer Cells and Metastasis
  • Galectins and Cancer Biology

Notable recent papers authored or co-authored by Daniela Wesch include:

  • Selection of cross-reactive T cells by commensal and food-derived yeasts drives cytotoxic TH1 cell responses in Crohn's disease, 2023, Nature Medicine
  • Initiation of Pancreatic Cancer: The Interplay of Hyperglycemia and Macrophages Promotes the Acquisition of Malignancy-Associated Properties in Pancreatic Ductal Epithelial Cells, 2021, International Journal of Molecular Sciences
  • Tumor resistance mechanisms and their consequences on γδ T cell activation, 2020, Immunological Reviews
  • Affinity Maturation of B7-H6 Translates into Enhanced NK Cell-Mediated Tumor Cell Lysis and Improved Proinflammatory Cytokine Release of Bispecific Immunoligands via NKp30 Engagement, 2020, The Journal of Immunology
  • Influence of Indoleamine-2,3-Dioxygenase and Its Metabolite Kynurenine on γδ T Cell Cytotoxicity against Ductal Pancreatic Adenocarcinoma Cells, 2020, Cells

Frequent collaborators in Daniela Wesch's work include:

  • Hans-Heinrich Oberg
  • Matthias Peipp
  • Dieter Kabelitz
  • Susanne Sebens
  • Dirk Bauerschlag

The scientist publishes regularly in several journals and has contributed notably to:

  • Frontiers in Immunology
  • Cells
  • Journal of Leukocyte Biology
  • Cancer Research
  • Regular and Young Investigator Award Abstracts

Best Publications

  • Perspectives of γδ T Cells in Tumor Immunology

    Dieter Kabelitz;Daniela Wesch;Wei He

  • Lysis of a broad range of epithelial tumour cells by human gamma delta T cells: Involvement of NKG2D ligands and T-cell receptor- versus NKG2D-dependent recognition

    P. Wrobel;H. Shojaei;B. Schittek;F. Gieseler

  • The γδTCR combines innate immunity with adaptive immunity by utilizing spatially distinct regions for agonist selection and antigen responsiveness.

    Daisy Melandri;Daisy Melandri;Iva Zlatareva;Iva Zlatareva;Raphaël A.G. Chaleil;Robin J. Dart;Robin J. Dart

  • Shedding of endogenous MHC class I-related chain molecules A and B from different human tumor entities: heterogeneous involvement of the "a disintegrin and metalloproteases" 10 and 17.

    Guranda Chitadze;Marcus Lettau;Jaydeep Bhat;Daniela Wesch

  • Characterization of Tumor Reactivity of Human Vγ9Vδ2 γδ T Cells In Vitro and in SCID Mice In Vivo

    Dieter Kabelitz;Daniela Wesch;Elke Pitters;Margot Zöller

  • Patterns of Chemokine Receptor Expression on Peripheral Blood γδ T Lymphocytes: Strong Expression of CCR5 Is a Selective Feature of Vδ2/Vγ9 γδ T Cells

    Andrea Glatzel;Daniela Wesch;Florian Schiemann;Ernst Brandt

  • Direct Costimulatory Effect of TLR3 Ligand Poly(I:C) on Human γδ T Lymphocytes

    Daniela Wesch;Susann Beetz;Hans-Heinrich Oberg;Matthias Marget

  • Innate immune functions of human γδ T cells

    Susann Beetz;Daniela Wesch;Lothar Marischen;Stefan Welte

  • Differentiation of Resting Human Peripheral Blood γδ T Cells toward Th1- or Th2-Phenotype

    Daniela Wesch;Andrea Glatzel;Dieter Kabelitz

  • Novel Bispecific Antibodies Increase γδ T-Cell Cytotoxicity against Pancreatic Cancer Cells

    Hans-Heinrich Oberg;Matthias Peipp;Christian Kellner;Susanne Sebens

  • Modulation of γδ T cell responses by TLR ligands

    Daniela Wesch;Christian Peters;Hans-Heinrich Oberg;Kathrin Pietschmann

  • Antigen Recognition by Human γδ T Lymphocytes

    Dieter Kabelitz;Andrea Glatzel;Daniela Wesch

  • Features and functions of gamma delta T lymphocytes: focus on chemokines and their receptors.

    Dieter Kabelitz;Daniela Wesch

  • Differential expression of CD126 and CD130 mediates different STAT-3 phosphorylation in CD4+CD25− and CD25high regulatory T cells

    Hans-Heinrich Oberg;Daniela Wesch;Sandra Grüssel;Stefan Rose-John

  • Regulation of regulatory T cells: role of dendritic cells and toll-like receptors.

    Dieter Kabelitz;Daniela Wesch;Hans-Heinrich Oberg

  • Primary activation of V gamma 9-expressing gamma delta T cells by Mycobacterium tuberculosis. Requirement for Th1-type CD4 T cell help and inhibition by IL-10.

    K Pechhold;D Wesch;S Schondelmaier;D Kabelitz

  • Toll-like receptors 3 and 7 agonists enhance tumor cell lysis by human gammadelta T cells.

    Hamed Shojaei;Hans-Heinrich Oberg;Matthias Juricke;Lothar Marischen

  • Regulation of T cell activation by TLR ligands.

    Hans-Heinrich Oberg;Matthias Juricke;Dieter Kabelitz;Daniela Wesch

  • Phenotype and regulation of immunosuppressive Vδ2-expressing γδ T cells

    Christian Peters;Hans‑Heinrich Oberg;Dieter Kabelitz;Daniela Wesch

  • Sex-specific phenotypical and functional differences in peripheral human Vγ9/Vδ2 T cells

    Nadia Caccamo;Francesco Dieli;Daniela Wesch;Hassan Jomaa

  • Toll-like receptor expression and function in subsets of human gammadelta T lymphocytes.

    K. Pietschmann;S. Beetz;S. Welte;I. Martens

  • Differential but Direct Abolishment of Human Regulatory T Cell Suppressive Capacity by Various TLR2 Ligands

    Hans-Heinrich Oberg;Thi Thuy Hoa Ly;Sandra Ussat;Tim Meyer

Frequent Co-Authors

Dieter Kabelitz
Dieter Kabelitz Kiel University
Matthias Peipp
Matthias Peipp Kiel University
Christoph Röcken
Christoph Röcken Kiel University
Ottmar Janssen
Ottmar Janssen Kiel University
Thomas S. Becker
Thomas S. Becker University of Sydney
Wolfgang W. A. Schamel
Wolfgang W. A. Schamel University of Freiburg
Bence Sipos
Bence Sipos University of Tübingen
Ole Ammerpohl
Ole Ammerpohl University of Ulm
Stefan Rose-John
Stefan Rose-John Kiel University
Margot Zöller
Margot Zöller Heidelberg University

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