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Neuroscience

D-Index
73
Citations
14976
World Ranking
2246
National Ranking
1067

Overview

Stephen D. Ginsberg is affiliated with the Nathan Kline Institute for Psychiatric Research in the United States. Their research primarily intersects the fields of medicine, biochemistry, genetics and molecular biology, and neuroscience, with a particular emphasis on physiology, molecular biology, neurology, public health, environmental and occupational health, as well as psychiatry and mental health.

Their work covers a range of topics including Alzheimer's disease research and treatments, neuroinflammation and neurodegeneration mechanisms, Down syndrome and intellectual disability research, dementia and cognitive impairment research, computational drug discovery methods, tryptophan and brain disorders, and bioinformatics and genomic networks.

Frequent publication venues for their research include:

  • Frontiers in Aging Neuroscience
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Alzheimer s & Dementia
  • Acta Neuropathologica Communications

Co-authors who frequently collaborate with Stephen D. Ginsberg are:

  • Melissa J. Alldred
  • Elliott J. Mufson
  • Gabriela Chiosis
  • Sang H. Lee
  • Adriana Heguy

Among their recent publications are the following papers:

  • "Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease," 2020, Journal of Clinical Investigation
  • "Mitovesicles are a novel population of extracellular vesicles of mitochondrial origin altered in Down syndrome," 2021, Science Advances
  • "The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction," 2020, Nature Communications
  • "Effects of early-life penicillin exposure on the gut microbiome and frontal cortex and amygdala gene expression," 2021, iScience
  • "A method for quantification of vesicular compartments within cells using 3D reconstructed confocal z-stacks: Comparison of ImageJ and Imaris to count early endosomes within basal forebrain cholinergic neurons," 2020, Journal of Neuroscience Methods

Best Publications

  • Cholinergic system during the progression of Alzheimer's disease: therapeutic implications.

    Elliott J Mufson;Scott E Counts;Sylvia E Perez;Stephen D Ginsberg

  • Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease

    Ethan R. Roy;Baiping Wang;Ying-Wooi Wan;Gabriel S. Chiu

  • Expression profile of transcripts in Alzheimer's disease tangle-bearing CA1 neurons.

    Stephen D. Ginsberg;Scott E. Hemby;Virginia M.‐Y. Lee;James H. Eberwine

  • Human cholinergic basal forebrain: chemoanatomy and neurologic dysfunction

    Elliott J. Mufson;Stephen D. Ginsberg;Milos D. Ikonomovic;Steven T. DeKosky

  • Autophagy flux in CA1 neurons of Alzheimer hippocampus: Increased induction overburdens failing lysosomes to propel neuritic dystrophy.

    Matteo Bordi;Martin J Berg;Panaiyur S Mohan;Corrinne M Peterhoff

  • Alzheimer’s-related endosome dysfunction in Down syndrome is Aβ-independent but requires APP and is reversed by BACE-1 inhibition

    Ying Jiang;Kerry A. Mullaney;Corrinne M. Peterhoff;Shaoli Che

  • Locus coeruleus cellular and molecular pathology during the progression of Alzheimer’s disease

    Sarah C. Kelly;Bin He;Sylvia E. Perez;Stephen D. Ginsberg;Stephen D. Ginsberg

  • Mild cognitive impairment: pathology and mechanisms

    Elliott J. Mufson;Lester Binder;Scott E. Counts;Steven T. DeKosky

  • Down regulation of trk but not p75NTR gene expression in single cholinergic basal forebrain neurons mark the progression of Alzheimer's disease

    Stephen D. Ginsberg;Shaoli Che;Joanne Wuu;Scott E. Counts

  • Microarray Analysis of Hippocampal CA1 Neurons Implicates Early Endosomal Dysfunction During Alzheimer's Disease Progression

    Stephen D. Ginsberg;Stephen D. Ginsberg;Melissa J. Alldred;Melissa J. Alldred;Scott E. Counts;Anne M. Cataldo

  • Gene Expression Profile for Schizophrenia: Discrete Neuron Transcription Patterns in the Entorhinal Cortex

    Scott E. Hemby;Stephen D. Ginsberg;Brian Brunk;Steven E. Arnold

  • Decreased brain-derived neurotrophic factor depends on amyloid aggregation state in transgenic mouse models of Alzheimer's disease

    Shiyong Peng;Diego J. Garzon;Diego J. Garzon;Monica Marchese;William Klein

  • An essential component in steroid synthesis, the steroidogenic acute regulatory protein, is expressed in discrete regions of the brain.

    Steven R. King;Pulak R. Manna;Tomohiro Ishii;Peter J. Syapin

  • Reduction of cortical TrkA but not p75(NTR) protein in early-stage Alzheimer's disease.

    Scott E. Counts;Muhammad Nadeem;Joanne Wuu;Stephen D. Ginsberg

  • Predominance of neuronal mRNAs in individual Alzheimer's disease senile plaques

    Stephen D. Ginsberg;Peter B. Crino;Scott E. Hemby;Jeremy A. Weingarten

  • Sequestration of RNA in Alzheimer's disease neurofibrillary tangles and senile plaques

    Stephen D. Ginsberg;Peter B. Crino;Virginia M.-Y. Lee;James H. Eberwine

  • Target identification for CNS diseases by transcriptional profiling.

    C Anthony Altar;Marquis P Vawter;Stephen D Ginsberg

  • PRESENCE AND PHOSPHORYLATION OF TRANSCRIPTION FACTORS IN DEVELOPING DENDRITES

    Peter Crino;Kamran Khodakhah;Kevin Becker;Stephen Ginsberg

  • Mechanisms underlying insulin deficiency-induced acceleration of β-amyloidosis in a mouse model of Alzheimer's disease.

    Latha Devi;Melissa J. Alldred;Melissa J. Alldred;Stephen D. Ginsberg;Stephen D. Ginsberg;Masuo Ohno;Masuo Ohno

  • Hippocampal plasticity during the progression of Alzheimer's disease

    E.J. Mufson;L. Mahady;D. Waters;S.E. Counts

  • Down regulation of trk but not p75 NTR gene expression in single cholinergic basal forebrain neurons mark the progression of Alzheimer's disease

    Stephen D. Ginsberg;Shaoli Che;Joanne Wuu;Scott E. Counts

Frequent Co-Authors

Elliott J. Mufson
Elliott J. Mufson Barrow Neurological Institute
Scott E. Counts
Scott E. Counts Michigan State University
Ralph A. Nixon
Ralph A. Nixon Nathan Kline Institute for Psychiatric Research
Sylvia E. Perez
Sylvia E. Perez Barrow Neurological Institute
Barbara J. Strupp
Barbara J. Strupp Cornell University
John Q. Trojanowski
John Q. Trojanowski University of Pennsylvania
Milos D. Ikonomovic
Milos D. Ikonomovic University of Pittsburgh
Scott E. Hemby
Scott E. Hemby High Point University
Joanne Wuu
Joanne Wuu University of Miami
Lee J. Martin
Lee J. Martin Johns Hopkins University School of Medicine

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