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Biology and Biochemistry

D-Index
65
Citations
14798
World Ranking
9167
National Ranking
4066

Overview

Matthew W. Kelley is affiliated with the National Institutes of Health in the United States. Their research predominantly focuses on biochemistry, genetics, and molecular biology, with significant contributions to neuroscience.

The primary fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Neuroscience

Subfields of expertise encompass:

  • Molecular Biology
  • Sensory Systems
  • Cognitive Neuroscience
  • Cancer Research
  • Otorhinolaryngology

The main topics of their research work are:

  • Hearing, Cochlea, Tinnitus, Genetics
  • Hearing Loss and Rehabilitation
  • Single-cell and spatial transcriptomics
  • Cancer-related molecular mechanisms research
  • Gene expression and cancer classification
  • Molecular Biology Techniques and Applications
  • Congenital heart defects research

Significant recent publications by Matthew W. Kelley include:

  • Characterization of the development of the mouse cochlear epithelium at the single cell level, 2020, Nature Communications
  • gEAR: Gene Expression Analysis Resource portal for community-driven, multi-omic data exploration, 2021, Nature Methods
  • Characterizing Adult Cochlear Supporting Cell Transcriptional Diversity Using Single-Cell RNA-Seq: Validation in the Adult Mouse and Translational Implications for the Adult Human Cochlea, 2020, Frontiers in Molecular Neuroscience
  • Short-term NAD+ supplementation prevents hearing loss in mouse models of Cockayne syndrome, 2020, npj Aging and Mechanisms of Disease
  • Specification of neuronal subtypes in the spiral ganglion begins prior to birth in the mouse, 2022, Proceedings of the National Academy of Sciences

Frequent co-authors collaborating with Kelley include:

  • Shahar Taiber
  • Karen B. Avraham
  • Michael C. Kelly
  • Ronna Hertzano
  • Alejandro Anaya-Rocha

Their research is often published in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Molecular Neuroscience
  • Journal of Neuroscience
  • Frontiers in Cell and Developmental Biology
  • Journal of Investigative Dermatology

Best Publications

  • Vascular development in the retina and inner ear: Control by Norrin and frizzled-4, a high-affinity ligand-receptor pair

    Qiang Xu;Yanshu Wang;Alain Dabdoub;Philip M Smallwood

  • Identification of Vangl2 and Scrb1 as planar polarity genes in mammals

    Mireille Montcouquiol;Rivka A. Rachel;Pamela J. Lanford;Neal G. Copeland

  • Notch signalling pathway mediates hair cell development in mammalian cochlea.

    Pamela J. Lanford;Yu Lan;Rulang Jiang;Claire Lindsell

  • Math1 regulates development of the sensory epithelium in the mammalian cochlea.

    Chad Woods;Mireille Montcouquiol;Matthew W Kelley

  • Regulation of cell fate in the sensory epithelia of the inner ear.

    Matthew W Kelley

  • Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea

    Alain Dabdoub;Chandrakala Puligilla;Jennifer M. Jones;Bernd Fritzsch

  • Asymmetric Localization of Vangl2 and Fz3 Indicate Novel Mechanisms for Planar Cell Polarity in Mammals

    Mireille Montcouquiol;Mireille Montcouquiol;Nathalie Sans;Nathalie Sans;David Huss;Jacob Kach

  • Massively Parallel Single Nucleus Transcriptional Profiling Defines Spinal Cord Neurons and Their Activity during Behavior.

    Anupama Sathyamurthy;Kory R. Johnson;Kaya J.E. Matson;Courtney I. Dobrott

  • From placode to polarization: new tunes in inner ear development

    Kate F. Barald;Matthew W. Kelley

  • Wnt signaling mediates reorientation of outer hair cell stereociliary bundles in the mammalian cochlea.

    Alain Dabdoub;Maura J. Donohue;Angela Brennan;Vladimir Wolf

  • Transcription profiling of inner ears from Pou4f3ddl/ddl identifies Gfi1 as a target of the Pou4f3 deafness gene

    Ronna Hertzano;Ronna Hertzano;Mireille Montcouquiol;Sharon Rashi-Elkeles;Rani Elkon

  • Characterization of the development of the mouse cochlear epithelium at the single cell level

    Likhitha Kolla;Michael C. Kelly;Zoe F. Mann;Alejandro Anaya-Rocha

  • Noncanonical Wnt signaling and neural polarity.

    Mireille Montcouquiol;E. Bryan Crenshaw;Matthew W. Kelley

  • Single-cell RNA-Seq resolves cellular complexity in sensory organs from the neonatal inner ear

    Joseph C. Burns;Michael C. Kelly;Michael Hoa;Robert J. Morell

  • The developing organ of Corti contains retinoic acid and forms supernumerary hair cells in response to exogenous retinoic acid in culture

    Matthew W. Kelley;Xiao-Mei Xu;Michael A. Wagner;Mark E. Warchol

  • Expression of Math1 and HES5 in the cochleae of wildtype and Jag2 mutant mice.

    Pamela J. Lanford;Ranu Shailam;Christine R. Norton;Thomas Ridley

  • Molecular Mechanisms of Inner Ear Development

    Doris K. Wu;Matthew W. Kelley

  • Type 2 iodothyronine deiodinase expression in the cochlea before the onset of hearing.

    Angel Campos-Barros;Lori L. Amma;Jonathan S. Faris;Ranu Shailam

  • Retardation of cochlear maturation and impaired hair cell function caused by deletion of all known thyroid hormone receptors.

    Alfons Rüsch;Lily Ng;Richard Goodyear;Dominik Oliver

  • Erratum: Regulation of cell fate in the sensory epithelia of the inner ear

    Matthew W. Kelley

Frequent Co-Authors

Mireille Montcouquiol
Mireille Montcouquiol Inserm : Institut national de la santé et de la recherche médicale
Jeffrey T. Corwin
Jeffrey T. Corwin University of Virginia
Thomas B. Friedman
Thomas B. Friedman National Institutes of Health
Karen B. Avraham
Karen B. Avraham Tel Aviv University
Ronald S. Petralia
Ronald S. Petralia National Institutes of Health
Robert J. Morell
Robert J. Morell National Institutes of Health
Andrew J. Griffith
Andrew J. Griffith National Institutes of Health
Anand Swaroop
Anand Swaroop National Institutes of Health
Neal G. Copeland
Neal G. Copeland The University of Texas MD Anderson Cancer Center
Nancy A. Jenkins
Nancy A. Jenkins The University of Texas MD Anderson Cancer Center

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