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Neuroscience

D-Index
41
Citations
5701
World Ranking
7926
National Ranking
3406

Overview

Mark E. Warchol is affiliated with Washington University in St. Louis in the United States. Their research portfolio spans multiple fields with a primary focus on neuroscience and related disciplines such as biochemistry, genetics, and molecular biology. The scientist's work extensively covers sensory systems, immunology, neurology, cognitive neuroscience, and cell biology.

Their main research topics include hearing, cochlea, tinnitus, genetics, and issues related to hearing loss and rehabilitation. Additional focal areas address vestibular and auditory disorders, immune response and inflammation, marine animal studies, Hippo pathway signaling and YAP/TAZ, as well as aquaculture disease management and microbiota.

Mark E. Warchol has contributed to a range of publication venues, with frequent appearances in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Scientific Reports
  • Journal of Neuroscience
  • Science Advances
  • Proceedings of the National Academy of Sciences

Collaborative work is an important aspect of their career. Frequent co-authors include:

  • Lavinia Sheets
  • Tejbeer Kaur
  • Angela Schrader
  • Vikrant Borse
  • Kevin K. Ohlemiller

Among their recent publications are the following:

  • Macrophages Promote Repair of Inner Hair Cell Ribbon Synapses following Noise-Induced Cochlear Synaptopathy, 2023, Journal of Neuroscience
  • Organ of Corti size is governed by Yap/Tead-mediated progenitor self-renewal, 2020, Proceedings of the National Academy of Sciences
  • Macrophage depletion protects against cisplatin-induced ototoxicity and nephrotoxicity, 2024, Science Advances
  • Cisplatin exposure acutely disrupts mitochondrial bioenergetics in the zebrafish lateral-line organ, 2022, Hearing Research
  • Macrophages Respond Rapidly to Ototoxic Injury of Lateral Line Hair Cells but Are Not Required for Hair Cell Regeneration, 2021, Frontiers in Cellular Neuroscience

In addition to journal articles, Mark E. Warchol has authored a book titled Hair Cell Regeneration, published by Springer Nature in 2023.

Best Publications

  • Regenerative proliferation in inner ear sensory epithelia from adult guinea pigs and humans

    Mark E. Warchol;Paul R. Lambert;Bradley J. Goldstein;Andrew Forge

  • Asymmetric Localization of Vangl2 and Fz3 Indicate Novel Mechanisms for Planar Cell Polarity in Mammals

    Mireille Montcouquiol;Mireille Montcouquiol;Nathalie Sans;Nathalie Sans;David Huss;Jacob Kach

  • Neural coding in the chick cochlear nucleus.

    Mark E. Warchol;Peter Dallos

  • The developing organ of Corti contains retinoic acid and forms supernumerary hair cells in response to exogenous retinoic acid in culture

    Matthew W. Kelley;Xiao-Mei Xu;Michael A. Wagner;Mark E. Warchol

  • Auditory Hair Cells: Structure, Function, Development, and Regeneration

    Jeffrey T. Corwin;Mark E. Warchol

  • Inhibition of Caspases Prevents Ototoxic and Ongoing Hair Cell Death

    Jonathan I. Matsui;Judith M. Ogilvie;Mark E. Warchol

  • Regenerative Proliferation in Organ Cultures of the Avian Cochlea: Identification of the Initial Progenitors and Determination of the Latency of the Proliferative Response

    Mark E. Warchol;Jeffrey T. Corwin

  • Fractalkine Signaling Regulates Macrophage Recruitment into the Cochlea and Promotes the Survival of Spiral Ganglion Neurons after Selective Hair Cell Lesion

    Tejbeer Kaur;Darius Zamani;Ling Tong;Edwin W. Rubel

  • Sensory regeneration in the vertebrate inner ear: differences at the levels of cells and species.

    Mark E. Warchol

  • Hair cell regeneration: the identities of progenitor cells, potential triggers and instructive cues.

    Jeffrey T. Corwin;Jay E. Jones;Akiko Katayama;Matthew W. Kelley

  • Critical signaling events during the aminoglycoside‐induced death of sensory hair cells in vitro

    Jonathan I. Matsui;Jonathan E. Gale;Mark E. Warchol

  • Caspase Inhibitors Promote Vestibular Hair Cell Survival and Function after Aminoglycoside Treatment In Vivo

    Jonathan I. Matsui;Asim Haque;David Huss;Elizabeth P. Messana

  • Differentiation of the lateral compartment of the cochlea requires a temporally restricted FGF20 signal

    Sung Ho Huh;Jennifer Jones;Mark E. Warchol;David M. Ornitz

  • Otopetrin 1 is required for otolith formation in the zebrafish Danio rerio.

    Inna Hughes;Brian Blasiole;David Huss;Mark E. Warchol

  • Cellular mechanisms of aminoglycoside ototoxicity.

    Mark E Warchol

  • Cell death, cell proliferation, and estimates of hair cell life spans in the vestibular organs of chicks

    J. Kil;M.E. Warchol;J.T. Corwin

  • Gene expression differences in quiescent versus regenerating hair cells of avian sensory epithelia: implications for human hearing and balance disorders

    R. David Hawkins;Stavros Bashiardes;Cynthia A. Helms;Lydia Hu

  • Overexpression of Bcl-2 prevents neomycin-induced hair cell death and caspase-9 activation in the adult mouse utricle in vitro

    Lisa L. Cunningham;Jonathan I. Matsui;Mark E. Warchol;Edwin W. Rubel

  • The Transcriptome of Utricle Hair Cell Regeneration in the Avian Inner Ear

    Yuan Chieh Ku;Nicole A. Renaud;Rose A. Veile;Cynthia Helms

  • Macrophage activity in organ cultures of the avian cochlea: demonstration of a resident population and recruitment to sites of hair cell lesions.

    Mark E. Warchol

  • Cell Density and N-Cadherin Interactions Regulate Cell Proliferation in the Sensory Epithelia of the Inner Ear

    Mark E. Warchol

  • Selective deletion of cochlear hair cells causes rapid age-dependent changes in spiral ganglion and cochlear nucleus neurons.

    Ling Tong;Melissa K. Strong;Tejbeer Kaur;Jose M. Juiz

Frequent Co-Authors

Jeffrey T. Corwin
Jeffrey T. Corwin University of Virginia
Michael Lovett
Michael Lovett Washington University in St. Louis
Kevin K. Ohlemiller
Kevin K. Ohlemiller Washington University in St. Louis
Mireille Montcouquiol
Mireille Montcouquiol Inserm : Institut national de la santé et de la recherche médicale
Guy P. Richardson
Guy P. Richardson University of Sussex
Edwin W. Rubel
Edwin W. Rubel University of Washington
J. David Dickman
J. David Dickman Baylor College of Medicine
Andrew Forge
Andrew Forge University College London
Neal G. Copeland
Neal G. Copeland The University of Texas MD Anderson Cancer Center
Nancy A. Jenkins
Nancy A. Jenkins The University of Texas MD Anderson Cancer Center

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