Albert S.B. Edge focuses on Cochlea, Stem cell, Hair cell, Cell biology and Neuroscience. His study in Cochlea focuses on Cochlear nerve in particular. His research investigates the connection between Stem cell and topics such as Organ of Corti that intersect with problems in Spiral ganglion and Adult stem cell.
The study incorporates disciplines such as Progenitor cell and Cellular differentiation in addition to Hair cell. His Cellular differentiation research incorporates elements of Cell cycle and Wnt signaling pathway. His biological study spans a wide range of topics, including Neurosphere, Auditory brainstem response, Directed differentiation and Neuroepithelial cell.
The scientist’s investigation covers issues in Cochlea, Cell biology, Hair cell, Neuroscience and Stem cell. His Cochlea research incorporates themes from Molecular biology, LGR5 and Regeneration. His Cell biology research includes themes of Inner ear, Immunology and Hair cell differentiation.
The Hair cell study combines topics in areas such as Synaptopathy and Protein degradation. His Neuroscience study which covers Embryonic stem cell that intersects with Neural crest and Neurogenesis. His studies deal with areas such as Endothelial stem cell, Cellular differentiation, Adult stem cell, Anatomy and Transplantation as well as Stem cell.
His scientific interests lie mostly in Cochlea, Cell biology, Regeneration, Neuroscience and Inner ear. He is involved in the study of Cochlea that focuses on Hair cell in particular. His work carried out in the field of Hair cell brings together such families of science as SOX2 and Synaptopathy.
His study in Cell biology is interdisciplinary in nature, drawing from both Cell and Hair cell differentiation. In his research, Auditory neuropathy is intimately related to Auditory brainstem response, which falls under the overarching field of Neuroscience. His study focuses on the intersection of Inner ear and fields such as Progenitor cell with connections in the field of Induced pluripotent stem cell.
Cell biology, Progenitor cell, Inner ear, Cochlea and Regeneration are his primary areas of study. His Cell biology research is multidisciplinary, relying on both Mutation, Reprogramming and Downregulation and upregulation. He combines subjects such as Ex vivo, Hair cell differentiation, Gene silencing, Epigenetics and LGR5 with his study of Progenitor cell.
The concepts of his Inner ear study are interwoven with issues in Cell growth, Organoid, Mechanotransduction, Stem cell and Induced pluripotent stem cell. As part of his studies on Regeneration, Albert S.B. Edge often connects relevant subjects like Neuroscience. His Wnt signaling pathway research is multidisciplinary, incorporating elements of Cell, RNA, Transcriptional response, Notch signaling pathway and In vivo.
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A promoter-level mammalian expression atlas
Alistair R.R. Forrest;Hideya Kawaji;Michael Rehli;J. Kenneth Baillie.
Nature (2014)
Deglycosylation of glycoproteins by trifluoromethanesulfonic acid.
Albert S.B. Edge;Connie R. Faltynek;Liselotte Hof;Leo E. Reichert.
Analytical Biochemistry (1981)
Autologous skeletal myoblasts transplanted to ischemia-damaged myocardium in humans. Histological analysis of cell survival and differentiation.
Francis D Pagani;Harout DerSimonian;Agatha Zawadzka;Kristie Wetzel.
Journal of the American College of Cardiology (2003)
Histological evidence of fetal pig neural cell survival after transplantation into a patient with Parkinson's disease
Terrence Deacon;James Schumacher;Jonathan Dinsmore;Christine Thomas.
Nature Medicine (1997)
Cell Therapy Attenuates Deleterious Ventricular Remodeling and Improves Cardiac Performance After Myocardial Infarction
Mohit Jain;Harout DerSimonian;Daniel A. Brenner;Soeun Ngoy.
Circulation (2001)
Notch Inhibition Induces Cochlear Hair Cell Regeneration and Recovery of Hearing after Acoustic Trauma
Kunio Mizutari;Masato Fujioka;Masato Fujioka;Masato Fujioka;Makoto Hosoya;Naomi Bramhall;Naomi Bramhall.
Neuron (2013)
Differential Distribution of Stem Cells in the Auditory and Vestibular Organs of the Inner Ear
Kazuo Oshima;Kazuo Oshima;Christian M. Grimm;C. Eduardo Corrales;C. Eduardo Corrales;Pascal Senn.
Jaro-journal of The Association for Research in Otolaryngology (2007)
Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery.
Holly A. Rees;Holly A. Rees;Holly A. Rees;Alexis C. Komor;Alexis C. Komor;Alexis C. Komor;Wei-Hsi Yeh;Joana Caetano-Lopes;Joana Caetano-Lopes.
Nature Communications (2017)
Wnt Responsive Lgr5-Expressing Stem Cells Are Hair Cell Progenitors in the Cochlea
Fuxin Shi;Judith S. Kempfle;Albert S. B. Edge.
The Journal of Neuroscience (2012)
Central Gain Restores Auditory Processing following Near-Complete Cochlear Denervation.
Anna R. Chambers;Jennifer Resnik;Jennifer Resnik;Yasheng Yuan;Jonathon P. Whitton.
Neuron (2016)
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